metronidazole has been researched along with Dermatitis Medicamentosa in 47 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of 16-year-old woman who developed pruritic eruptions after oral metronidazole treatment for diarrhea." | 7.80 | Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by oral metronidazole. ( Bayramgürler, D; Odyakmaz Demirsoy, E; Salman, S; Şikar Aktürk, A; Yıldız, KD, 2014) |
| " pylori-infected patients with endoscopically documented duodenal ulcer either currently or within the past year were randomized to 14 days of (1) lansoprazole, 30 mg bid, plus amoxicillin, 1 gm tid; (2) lansoprazole, 30 mg tid, plus amoxicillin, 1 gm tid; (3) lansoprazole, 30 mg tid alone; or (4) amoxicillin, 1 gm tid alone." | 5.08 | Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. ( Arora, A; Graham, D; Haber, M; Harford, W; Lanza, F; Rose, P; Siepman, N; Weissfeld, A, 1996) |
| "Twenty cancer patients being treated with EGFRIs were included in the study." | 3.85 | Pimecrolimus cream 1% for the treatment of papulopustular eruption related to epidermal growth factor receptor inhibitors: a case series and a literature review of therapeutic approaches. ( Antoniou, C; Katsambas, A; Kiagia, M; Nikolaou, C; Nikolaou, V; Stratigos, A; Syrigos, K, 2010) |
| " We report a case of 16-year-old woman who developed pruritic eruptions after oral metronidazole treatment for diarrhea." | 3.80 | Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by oral metronidazole. ( Bayramgürler, D; Odyakmaz Demirsoy, E; Salman, S; Şikar Aktürk, A; Yıldız, KD, 2014) |
| "A 68-year-old woman developed allergic contact dermatitis to topical metronidazole gel as proven by positive patch tests to the gel and to metronidazole." | 3.72 | Co-existing sensitivity to metronidazole and isothiazolinone. ( Matz, H; Orion, E; Wolf, R, 2003) |
| "Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory properties." | 2.46 | Innovative use of topical metronidazole. ( Zip, CM, 2010) |
| "Acute generalized exanthemic pustulosis often presents dramatically with the abrupt onset of a widespread pustular eruption on an erythematous base, with a frequently positive Nikolsky sign." | 1.29 | Acute generalized exanthemic pustulosis. ( Heymann, WR; Manders, SM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.38) | 18.7374 |
| 1990's | 10 (21.28) | 18.2507 |
| 2000's | 15 (31.91) | 29.6817 |
| 2010's | 14 (29.79) | 24.3611 |
| 2020's | 5 (10.64) | 2.80 |
| Authors | Studies |
|---|---|
| Dilley, M | 1 |
| Geng, B | 1 |
| Yang, F | 1 |
| Jiang, M | 1 |
| Zhang, W | 1 |
| Qiao, Y | 1 |
| Chen, SA | 1 |
| Wang, D | 1 |
| Zhu, H | 1 |
| Zhang, J | 1 |
| Qin, S | 1 |
| Zhu, Q | 1 |
| Lv, Y | 1 |
| Xing, Q | 1 |
| Luo, X | 1 |
| Zhang, H | 1 |
| Xie, Z | 1 |
| Kumagai, J | 1 |
| Nakamura, A | 1 |
| Ogawa, S | 1 |
| Washio, K | 1 |
| Özkaya, E | 1 |
| Nespoulous, L | 1 |
| Matei, I | 1 |
| Charissoux, A | 1 |
| Bédane, C | 1 |
| Assikar, S | 1 |
| Sobrino-García, M | 1 |
| Gómez-Cardeñosa, A | 1 |
| Moreno-Rodilla, E | 1 |
| Muñoz-Bellido, FJ | 1 |
| Lázaro-Sastre, M | 1 |
| Dávila, I | 1 |
| Yung, CC | 1 |
| Watts, TJ | 1 |
| Haque, R | 1 |
| Kumar, N | 1 |
| Sundriyal, D | 1 |
| Walia, M | 1 |
| Trisal, D | 1 |
| Boyd, AS | 1 |
| Ortleb, M | 1 |
| Şikar Aktürk, A | 1 |
| Bayramgürler, D | 1 |
| Salman, S | 1 |
| Yıldız, KD | 1 |
| Odyakmaz Demirsoy, E | 1 |
| Waldman, L | 1 |
| Reddy, SB | 1 |
| Kassim, A | 1 |
| Dettloff, J | 1 |
| Reddy, VB | 1 |
| Çekin, AH | 1 |
| Şahintürk, Y | 1 |
| Akbay Harmandar, F | 1 |
| Uyar, S | 1 |
| Yolcular, BO | 1 |
| Çekin, Y | 1 |
| Fernández-Jorge, B | 1 |
| Goday Buján, J | 1 |
| Fernández-Torres, R | 1 |
| Rodríguez-Lojo, R | 1 |
| Fonseca, E | 1 |
| Rashid Dar, N | 1 |
| Raza, N | 1 |
| Nikolaou, V | 1 |
| Stratigos, A | 1 |
| Antoniou, C | 1 |
| Kiagia, M | 1 |
| Nikolaou, C | 1 |
| Katsambas, A | 1 |
| Syrigos, K | 1 |
| Kumar, P | 1 |
| Parashette, KR | 1 |
| Noronha, P | 1 |
| Zip, CM | 1 |
| Sanmukhani, J | 1 |
| Shah, V | 1 |
| Baxi, S | 1 |
| Tripathi, C | 1 |
| Hermida, MD | 1 |
| Consalvo, L | 1 |
| Lapadula, MM | 1 |
| Della Giovanna, P | 1 |
| Cabrera, HN | 1 |
| Pongcharoen, P | 1 |
| Chanprapaph, K | 1 |
| Vachiramon, V | 1 |
| Short, KA | 1 |
| Fuller, LC | 1 |
| Salisbury, JR | 1 |
| Sehgal, VN | 1 |
| Khandpur, S | 1 |
| Sardana, K | 1 |
| Bajaj, P | 1 |
| Wolf, R | 1 |
| Orion, E | 1 |
| Matz, H | 1 |
| Criado, PR | 1 |
| de Oliveira Ramos, R | 1 |
| Vasconcellos, C | 1 |
| Jardim Criado, RF | 1 |
| Valente, NY | 1 |
| Brinkmeier, T | 1 |
| Herbst, RA | 1 |
| Schaller, J | 1 |
| Kuegler, K | 1 |
| Pirker, C | 1 |
| Beiteke, U | 1 |
| Grosshans, E | 1 |
| Frosch, PJ | 1 |
| Girardi, M | 1 |
| Duncan, KO | 1 |
| Tigelaar, RE | 1 |
| Imaeda, S | 1 |
| Watsky, KL | 2 |
| McNiff, JM | 1 |
| Prieto, A | 1 |
| De Barrio, M | 1 |
| Infante, S | 1 |
| Torres, A | 1 |
| Rubio, M | 1 |
| Olalde, S | 1 |
| Colón, LE | 1 |
| Johnson, LA | 1 |
| Gottschalk, RW | 1 |
| Madsen, JT | 1 |
| Thormann, J | 1 |
| Kerre, S | 1 |
| Andersen, KE | 1 |
| Goossens, A | 1 |
| Jiménez-Puya, R | 1 |
| Gómez-García, F | 1 |
| Rodríguez-Bujaldón, A | 1 |
| Moreno-Giménez, JC | 1 |
| Manders, SM | 1 |
| Heymann, WR | 1 |
| Vincenzi, C | 1 |
| Lucente, P | 1 |
| Ricci, C | 1 |
| Tosti, A | 1 |
| Sharma, R | 2 |
| Pickering, J | 1 |
| McCormack, WM | 1 |
| Harford, W | 1 |
| Lanza, F | 1 |
| Arora, A | 1 |
| Graham, D | 1 |
| Haber, M | 1 |
| Weissfeld, A | 1 |
| Rose, P | 1 |
| Siepman, N | 1 |
| Thami, GP | 1 |
| Kanwar, AJ | 2 |
| Mahboob, A | 1 |
| Haroon, TS | 1 |
| Gastaminza, G | 1 |
| Anda, M | 1 |
| Audicana, MT | 1 |
| Fernandez, E | 1 |
| Muñoz, D | 1 |
| Vila, JB | 1 |
| Bernier, MA | 1 |
| Gutierrez, JV | 1 |
| Gómez, MT | 1 |
| Polo, AM | 1 |
| Harrison, JM | 1 |
| Miranda-Romero, A | 1 |
| Muñoz, CM | 1 |
| Walfish, AE | 1 |
| Sapadin, AN | 1 |
| Naik, RP | 1 |
| Singh, G | 1 |
| Izu, R | 1 |
| Aguirre, A | 1 |
| González, M | 1 |
| Díaz-Pérez, JL | 1 |
| Rajagopalan, M | 1 |
| Kaur, S | 1 |
| Mishra, D | 1 |
| Mobashir, M | 1 |
| Zaheer, MS | 1 |
| Shelley, WB | 1 |
| Shelley, ED | 1 |
| Scott, F | 1 |
| Miller, MJ | 1 |
5 reviews available for metronidazole and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Immediate and Delayed Hypersensitivity Reactions to Antibiotics: Aminoglycosides, Clindamycin, Linezolid, and Metronidazole.
Topics: Aminoglycosides; Anaphylaxis; Angioedema; Anti-Bacterial Agents; Clindamycin; Dermatitis, Allergic C | 2022 |
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) associated with pristinamycin, secnidazole, and nefopam, with a review of the literature.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Antiprotozoal Agents; Drug Eruptions; | 2018 |
Vancomycin-associated neutrophilic dermatitis histologically mimicking Cryptococcus.
Topics: Biopsy, Needle; Coronary Artery Disease; Cryptococcus; Dermatomycoses; Diagnosis, Differential; Drug | 2014 |
Pimecrolimus cream 1% for the treatment of papulopustular eruption related to epidermal growth factor receptor inhibitors: a case series and a literature review of therapeutic approaches.
Topics: Aged; Antineoplastic Agents; Dermatologic Agents; Drug Eruptions; ErbB Receptors; Female; Humans; Ma | 2010 |
Innovative use of topical metronidazole.
Topics: Acute Generalized Exanthematous Pustulosis; Administration, Cutaneous; Adult; Anti-Infective Agents; | 2010 |
4 trials available for metronidazole and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Use of probiotics as an adjuvant to sequential H. pylori eradication therapy: impact on eradication rates, treatment resistance, treatment-related side effects, and patient compliance.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Amoxicillin; Anorexia; Anti-Bacteria | 2017 |
Pimecrolimus cream 1% for the treatment of papulopustular eruption related to epidermal growth factor receptor inhibitors: a case series and a literature review of therapeutic approaches.
Topics: Aged; Antineoplastic Agents; Dermatologic Agents; Drug Eruptions; ErbB Receptors; Female; Humans; Ma | 2010 |
Cumulative irritation potential among metronidazole gel 1%, metronidazole gel 0.75%, and azelaic acid gel 15%.
Topics: Administration, Topical; Adult; Dermatologic Agents; Dicarboxylic Acids; Drug Eruptions; Female; Gel | 2007 |
Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Diar | 1996 |
39 other studies available for metronidazole and Dermatitis Medicamentosa
| Article | Year |
|---|---|
HLA-A*24:02 is associated with metronidazole-induced cutaneous adverse drug reactions in Han Chinese individuals: A pilot case-control study with both HLA gene and T cell receptor repertoire analysis.
Topics: Adult; Aged; Alleles; Anti-Infective Agents; Asian People; Case-Control Studies; Drug Eruptions; Fem | 2020 |
Symmetrical drug-related intertriginous and flexural exanthema induced by metronidazole suppository.
Topics: Antifungal Agents; Drug Eruptions; Exanthema; Female; Humans; Metronidazole; Middle Aged; Suppositor | 2021 |
Intravaginal metronidazole ovule-related allergic contact dermatitis.
Topics: Administration, Intravaginal; Anti-Bacterial Agents; Dermatitis, Allergic Contact; Dose-Response Rel | 2021 |
Changing trends in inducer drugs of fixed drug eruption: a 20-year cross-sectional study from Turkey.
Topics: Cross-Sectional Studies; Drug Eruptions; Humans; Metronidazole; Naproxen; Ornidazole; Piroxicam; Tri | 2018 |
A case report of fixed drug eruption caused by several drugs because of cross-reactivity and co-sensitization.
Topics: Aged; Anti-Bacterial Agents; Cross Reactions; Drug Eruptions; Esomeprazole; Humans; Levofloxacin; Ma | 2019 |
Successful desensitization to metronidazole in a patient with generalized fixed drug eruption.
Topics: Desensitization, Immunologic; Drug Eruptions; Humans; Metronidazole | 2020 |
Metronidazole-induced fixed drug eruption.
Topics: Aged; Diagnosis, Differential; Drug Eruptions; Humans; Leg; Metronidazole; Skin | 2013 |
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by oral metronidazole.
Topics: Adolescent; Antitrichomonal Agents; Buttocks; Diarrhea; Drug Eruptions; Exanthema; Female; Humans; M | 2014 |
Neutrophilic Fixed Drug Eruption.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Drug Erupt | 2015 |
Concomitant allergic contact dermatitis from diphenhydramine and metronidazole.
Topics: Anti-Infective Agents; Dermatitis, Allergic Contact; Diphenhydramine; Drug Eruptions; Drug Therapy, | 2008 |
Drug induced linear IgA disease with unusual features: Koebner phenomenon, local insulin sensitivity and annular blister of the nipples.
Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Butylscopolammonium Bromide; Drug Eruptions; Huma | 2008 |
Letter: Perioral dermatitis in a child associated with an inhalation steroid.
Topics: Administration, Inhalation; Adolescent; Albuterol; Androstadienes; Anti-Asthmatic Agents; Asthma; Cl | 2010 |
Fixed drug eruption with ornidazole having cross-sensitivity to secnidazole but not to other nitro-imidazole compounds: a case report.
Topics: Adult; Antiprotozoal Agents; Biopsy; Cross Reactions; Drug Eruptions; Glucocorticoids; Humans; Male; | 2010 |
Bullous fixed drug eruption induced by intravaginal metronidazole ovules, with positive topical provocation test findings.
Topics: Administration, Intravaginal; Adult; Anti-Infective Agents; Arm; Cross Reactions; Drug Eruptions; Fe | 2011 |
Papulopustular eruptions in a 32-year-old woman after lung cancer treatment.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Antineoplastic Agents; Dermatologic Agents; Drug Erup | 2011 |
Fixed drug eruption following metronidazole therapy and the use of topical provocation testing in diagnosis.
Topics: Adult; Antitrichomonal Agents; Drug Eruptions; Female; Humans; Metronidazole; Skin Tests | 2002 |
Bullous fixed drug eruption (BFDE) following per-oral metronidazole.
Topics: Administration, Oral; Adult; Biopsy, Needle; Drug Eruptions; Drug Therapy, Combination; Follow-Up St | 2003 |
Co-existing sensitivity to metronidazole and isothiazolinone.
Topics: Aged; Anti-Infective Agents; Dermatitis, Contact; Drug Combinations; Drug Eruptions; Drug Interactio | 2003 |
Two case reports of cutaneous adverse reactions following hepatitis B vaccine: lichen planus and granuloma annulare.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Anti-Inflammatory Agents; Desonide; Dia | 2004 |
Drug-induced blaschkitis.
Topics: Adult; Biopsy, Needle; Drug Eruptions; Drug Interactions; Female; Follow-Up Studies; Humans; Immunoh | 2004 |
Cross-comparison of patch test and lymphocyte proliferation responses in patients with a history of acute generalized exanthematous pustulosis.
Topics: Adult; Aged; Anti-Infective Agents; Calcium Channel Blockers; Cell Proliferation; Diltiazem; Drug Er | 2005 |
Recurrent fixed drug eruption due to metronidazole elicited by patch test with tinidazole.
Topics: Adult; Antiprotozoal Agents; Antitrichomonal Agents; Cross Reactions; Drug Eruptions; Female; Humans | 2005 |
Allergic contact dermatitis to topical metronidazole - 3 cases.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Dermatitis, Allergic Contact; Drug Eruptions; | 2007 |
[Acute acneform eruption secondary to cetuximab with good response to metronidazole].
Topics: Acneiform Eruptions; Acute Disease; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Cetux | 2007 |
Acute generalized exanthemic pustulosis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Ampicillin; Cefazolin; Dermatitis, Exfoliative; Diagn | 1994 |
Facial contact dermatitis due to metronidazole.
Topics: Adult; Antifungal Agents; Dermatitis, Allergic Contact; Drug Eruptions; Facial Dermatoses; Female; H | 1997 |
Trichomoniasis in a postmenopausal woman cured after discontinuation of estrogen replacement therapy.
Topics: Antitrichomonal Agents; Drug Eruptions; Estrogen Replacement Therapy; Female; Humans; Hydrogen-Ion C | 1997 |
Fixed drug eruption due to metronidazole and tinidazole without cross-sensitivity to secnidazole.
Topics: Adult; Antiprotozoal Agents; Cross Reactions; Drug Eruptions; Giardiasis; Humans; Male; Metronidazol | 1998 |
Acute generalized exanthematous pustulosis induced by metronidazole: the role of patch testing.
Topics: Adult; Anti-Infective Agents; Drug Eruptions; Edema; Erythema; Exanthema; Humans; Male; Metronidazol | 1999 |
Fixed drug eruption with albendazole and it's cross-sensitivity with metronidazole--a case report.
Topics: Adult; Albendazole; Antiprotozoal Agents; Cross Reactions; Drug Eruptions; Female; Humans; Metronida | 1998 |
Fixed-drug eruption due to metronidazole with positive topical provocation.
Topics: Adult; Anti-Infective Agents; Cross Reactions; Drug Eruptions; Female; Humans; Intradermal Tests; Me | 2001 |
Fixed drug eruption caused by metronidazole.
Topics: Adult; Anti-Infective Agents; Drug Eruptions; Female; Humans; Metronidazole; Patch Tests | 2002 |
Fixed drug eruption due to doxycycline and metronidazole.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Eruptions; Erythema; Female; | 2002 |
Fixed drug eruption due to metronidazole.
Topics: Adult; Drug Eruptions; Humans; Male; Metronidazole | 1977 |
Contact dermatitis from tioconazole with cross-sensitivity to other imidazoles.
Topics: Adult; Antifungal Agents; Cross Reactions; Dermatitis, Contact; Drug Eruptions; Female; Humans; Imid | 1992 |
Fixed drug eruption due to tinidazole with cross-reactivity with metronidazole.
Topics: Adult; Drug Eruptions; Drug Interactions; Erythema; Humans; Male; Metronidazole; Nitroimidazoles; Ti | 1990 |
Fixed drug eruption and cross-reactivity between tinidazole and metronidazole.
Topics: Adult; Cross Reactions; Drug Eruptions; Humans; Male; Metronidazole; Penile Diseases; Tinidazole | 1990 |
Fixed drug eruption due to metronidazole.
Topics: Adult; Drug Eruptions; Female; Humans; Metronidazole | 1987 |
Trials with metronidazole in amebic dysentery.
Topics: Adolescent; Adult; Aged; Drug Eruptions; Dysentery, Amebic; Feces; Female; Hemagglutination Tests; H | 1970 |