metronidazole has been researched along with Dermatitis, Seborrheic in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Dermatitis, Seborrheic: A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "metronidazole 1% gel in the treatment of seborrheic dermatitis." | 2.78 | A double blind study of the effectiveness of sertaconazole 2% cream vs. metronidazole 1% gel in the treatment of seborrheic dermatitis. ( Goldust, M; Raghifar, R; Rezaee, E, 2013) |
| "Metronidazole gel was generally tolerated well during the study." | 2.71 | Is topical metronidazole effective in seborrheic dermatitis? A double-blind study. ( Altinyazar, HC; Eştürk, E; Koca, R, 2003) |
| "Forty-four patients with seborrheic dermatitis were enrolled in the study." | 2.70 | Topical metronidazole in seborrheic dermatitis--a double-blind study. ( Kumar, B; Negi, KS; Pandhi, R; Parsad, D, 2001) |
| "Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory properties." | 2.46 | Innovative use of topical metronidazole. ( Zip, CM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldust, M | 1 |
| Rezaee, E | 1 |
| Raghifar, R | 1 |
| Cicek, D | 1 |
| Kandi, B | 1 |
| Bakar, S | 1 |
| Turgut, D | 1 |
| Zip, CM | 1 |
| Koca, R | 1 |
| Altinyazar, HC | 1 |
| Eştürk, E | 1 |
| Seckin, D | 1 |
| Gurbuz, O | 1 |
| Akin, O | 1 |
| Parsad, D | 1 |
| Pandhi, R | 1 |
| Negi, KS | 1 |
| Kumar, B | 1 |
| Iudica, AC | 1 |
1 review available for metronidazole and Dermatitis, Seborrheic
| Article | Year |
|---|---|
Innovative use of topical metronidazole.
Topics: Acute Generalized Exanthematous Pustulosis; Administration, Cutaneous; Adult; Anti-Infective Agents; | 2010 |
5 trials available for metronidazole and Dermatitis, Seborrheic
| Article | Year |
|---|---|
A double blind study of the effectiveness of sertaconazole 2% cream vs. metronidazole 1% gel in the treatment of seborrheic dermatitis.
Topics: Adolescent; Adult; Antifungal Agents; Child; Dermatitis, Seborrheic; Double-Blind Method; Female; Hu | 2013 |
Pimecrolimus 1% cream, methylprednisolone aceponate 0.1% cream and metronidazole 0.75% gel in the treatment of seborrhoeic dermatitis: a randomized clinical study.
Topics: Administration, Cutaneous; Adolescent; Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-S | 2009 |
Is topical metronidazole effective in seborrheic dermatitis? A double-blind study.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Dermatitis, Seborrheic; Double-Blind Method; | 2003 |
Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Chi-Squar | 2007 |
Topical metronidazole in seborrheic dermatitis--a double-blind study.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Dermatitis, Seborrheic; Double-Blind Method; | 2001 |
1 other study available for metronidazole and Dermatitis, Seborrheic
| Article | Year |
|---|---|
Does treatment with topical metronidazole improve seborrheic dermatitis?
Topics: Administration, Cutaneous; Anti-Infective Agents; Dermatitis, Seborrheic; Evidence-Based Medicine; H | 2001 |