metronidazole has been researched along with Dental Fistula in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Dental Fistula: An abnormal passage in the oral cavity on the gingiva.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becerra, P | 1 |
| Ricucci, D | 1 |
| Loghin, S | 1 |
| Gibbs, JL | 1 |
| Lin, LM | 1 |
| Aminabadi, NA | 1 |
| Huang, B | 1 |
| Samiei, M | 1 |
| Agheli, S | 1 |
| Jamali, Z | 1 |
| Shirazi, S | 1 |
| Reynolds, K | 1 |
| Johnson, JD | 1 |
| Cohenca, N | 1 |
| Kargül, B | 1 |
| Tanboga, I | 1 |
| Altinok, B | 1 |
| Iwaya, SI | 1 |
| Ikawa, M | 1 |
| Kubota, M | 1 |
| Tronstad, L | 1 |
| Kreshtool, D | 1 |
| Barnett, F | 1 |
| Haapasalo, M | 1 |
| Ranta, K | 1 |
| Ranta, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative Clinical and Radiographic Study of 3Mixstatin vs Tri-Antibiotic Mix and Simvastatin in the Treatment of Primary Molars With Inflammatory Root Resorption A Randomized Clinical Trial[NCT03585751] | 45 participants (Anticipated) | Interventional | 2018-09-30 | Not yet recruiting | |||
| A Randomized Controlled Trial Comparing the Clinical and Radiographic Success of 3Mixtatin Versus Modified 3Mix in Lesion Sterilization and Tissue Repair (LSTR) for The Treatment of Necrotic Primary Molars[NCT05677945] | 24 participants (Anticipated) | Interventional | 2023-03-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for metronidazole and Dental Fistula
| Article | Year |
|---|---|
A Randomized Trial Using 3Mixtatin Compared to MTA in Primary Molars with Inflammatory Root Resorption: A Novel Endodontic Biomaterial.
Topics: Aluminum Compounds; Anti-Bacterial Agents; Calcium Compounds; Cefixime; Child; Child, Preschool; Cip | 2016 |
A Randomized Trial Using 3Mixtatin Compared to MTA in Primary Molars with Inflammatory Root Resorption: A Novel Endodontic Biomaterial.
Topics: Aluminum Compounds; Anti-Bacterial Agents; Calcium Compounds; Cefixime; Child; Child, Preschool; Cip | 2016 |
A Randomized Trial Using 3Mixtatin Compared to MTA in Primary Molars with Inflammatory Root Resorption: A Novel Endodontic Biomaterial.
Topics: Aluminum Compounds; Anti-Bacterial Agents; Calcium Compounds; Cefixime; Child; Child, Preschool; Cip | 2016 |
A Randomized Trial Using 3Mixtatin Compared to MTA in Primary Molars with Inflammatory Root Resorption: A Novel Endodontic Biomaterial.
Topics: Aluminum Compounds; Anti-Bacterial Agents; Calcium Compounds; Cefixime; Child; Child, Preschool; Cip | 2016 |
6 other studies available for metronidazole and Dental Fistula
| Article | Year |
|---|---|
Histologic study of a human immature permanent premolar with chronic apical abscess after revascularization/revitalization.
Topics: Aluminum Compounds; Anti-Bacterial Agents; Apexification; Bicuspid; Blood Coagulation; Calcification | 2014 |
Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bicuspid; Child; Ciprofloxacin; Dental Fistula; Dental | 2009 |
Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study.
Topics: Abscess; Alveolar Bone Loss; Anti-Infective Agents; Child; Dental Fistula; Dental Pulp Diseases; Fem | 2010 |
Revascularization of an immature permanent tooth with apical periodontitis and sinus tract.
Topics: Adolescent; Anti-Infective Agents, Local; Bicuspid; Ciprofloxacin; Dental Fistula; Dental Pulp; Dent | 2001 |
Microbiological monitoring and results of treatment of extraradicular endodontic infection.
Topics: Apicoectomy; Calcium Hydroxide; Dental Fistula; Dental Pulp Cavity; Female; Humans; Incisor; Metroni | 1990 |
Mixed anaerobic periapical infection with sinus tract.
Topics: Adult; Bacteria; Dental Fistula; Humans; Incisor; Male; Maxilla; Metronidazole; Periapical Abscess | 1987 |