metronidazole has been researched along with Dental Deposit in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Caries/pulpitis was the most common diagnosis (n = 222; 31% of cases), of which 48 (21%) were prescribed antibiotics." | 1.42 | Diagnosis and prescribing pattern of antibiotics and painkillers among dentists. ( Lundborg, CS; Marrone, G; Tanwir, F; Tariq, A, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanwir, F | 1 |
| Marrone, G | 1 |
| Tariq, A | 1 |
| Lundborg, CS | 1 |
| Matarazzo, F | 1 |
| Figueiredo, LC | 1 |
| Cruz, SE | 1 |
| Faveri, M | 1 |
| Feres, M | 1 |
1 trial available for metronidazole and Dental Deposit
| Article | Year |
|---|---|
Clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: a randomized placebo-controlled study.
Topics: Adult; Amoxicillin; Anti-Infective Agents; Bacteria; Chronic Periodontitis; Colony Count, Microbial; | 2008 |
1 other study available for metronidazole and Dental Deposit
| Article | Year |
|---|---|
Diagnosis and prescribing pattern of antibiotics and painkillers among dentists.
Topics: Adolescent; Adult; Amoxicillin; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; Cross-Se | 2015 |