Page last updated: 2024-10-31

metronidazole and Dens in Dente

metronidazole has been researched along with Dens in Dente in 1 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Dens in Dente: Anomaly of the tooth, found chiefly in upper lateral incisors. It is characterized by invagination of the enamel at the incisal edge.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jung, IY1
Lee, SJ1
Hargreaves, KM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Microbiological Evaluation of Single Versus Multiple Visits Regeneration Using MALDI-TOF Mass Spectrometry (A Randomized Controlled Clinical Trial)[NCT04533074]Phase 216 participants (Actual)Interventional2018-08-23Terminated (stopped due to due to the COVID-19 pandemic)
Randomized Controlled Research of Revascularization in Immature Permanent Teeth With Periapical Periodontitis[NCT01799187]190 participants (Anticipated)Interventional2012-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for metronidazole and Dens in Dente

ArticleYear
Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series.
    Journal of endodontics, 2008, Volume: 34, Issue:7

    Topics: Adolescent; Anti-Infective Agents, Local; Child; Ciprofloxacin; Dens in Dente; Dental Pulp; Dental P

2008
Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series.
    Journal of endodontics, 2008, Volume: 34, Issue:7

    Topics: Adolescent; Anti-Infective Agents, Local; Child; Ciprofloxacin; Dens in Dente; Dental Pulp; Dental P

2008
Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series.
    Journal of endodontics, 2008, Volume: 34, Issue:7

    Topics: Adolescent; Anti-Infective Agents, Local; Child; Ciprofloxacin; Dens in Dente; Dental Pulp; Dental P

2008
Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series.
    Journal of endodontics, 2008, Volume: 34, Issue:7

    Topics: Adolescent; Anti-Infective Agents, Local; Child; Ciprofloxacin; Dens in Dente; Dental Pulp; Dental P

2008