metronidazole has been researched along with DRESS Syndrome in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole was withdrawn and vancomycin was changed by teicoplanin 10 and 15 days later, respectively." | 5.91 | Cefotaxime-induced drug reaction with eosinophilia and systemic symptom in a child with cross-reactivity to other cephalosporins and cosensitization to teicoplanin. ( Aouam, K; Ben Fadhel, N; Ben Fredj, N; Ben Romdhane, H; Chaabane, A; Chadli, Z; Mansour, K, 2023) |
| "Metronidazole was withdrawn and vancomycin was changed by teicoplanin 10 and 15 days later, respectively." | 1.91 | Cefotaxime-induced drug reaction with eosinophilia and systemic symptom in a child with cross-reactivity to other cephalosporins and cosensitization to teicoplanin. ( Aouam, K; Ben Fadhel, N; Ben Fredj, N; Ben Romdhane, H; Chaabane, A; Chadli, Z; Mansour, K, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mansour, K | 1 |
| Ben Fadhel, N | 1 |
| Ben Fredj, N | 1 |
| Ben Romdhane, H | 1 |
| Chaabane, A | 2 |
| Chadli, Z | 2 |
| Aouam, K | 2 |
| Romdhane, HB | 1 |
| Brahim, HB | 1 |
| Fredj, NB | 1 |
| Boughattas, NA | 1 |
| Chakroun, M | 1 |
2 other studies available for metronidazole and DRESS Syndrome
| Article | Year |
|---|---|
Cefotaxime-induced drug reaction with eosinophilia and systemic symptom in a child with cross-reactivity to other cephalosporins and cosensitization to teicoplanin.
Topics: Adult; Cefotaxime; Cephalosporins; Child; Child, Preschool; Drug Hypersensitivity Syndrome; Eosinoph | 2023 |
Meglumine antimoniate-induced DRESS: original case with a positive skin test.
Topics: Animals; Antiprotozoal Agents; Cryotherapy; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; | 2018 |