metronidazole has been researched along with Cystitis in 15 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cystitis: Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 51-year-old woman with generalized lichen planus for 23 years experienced total involution of her lesions during metronidazole therapy." | 7.67 | Urinary tract infection as a cause of lichen planus: metronidazole therapy. ( Shelley, ED; Shelley, WB, 1984) |
| "A 51-year-old woman with generalized lichen planus for 23 years experienced total involution of her lesions during metronidazole therapy." | 3.67 | Urinary tract infection as a cause of lichen planus: metronidazole therapy. ( Shelley, ED; Shelley, WB, 1984) |
| "Hence the diagnosis of pseudomembranous colitis became apparent." | 1.40 | Emphysematous cystitis due to recurrent Clostridium difficile infection. ( Dees, A; Jonkman, JG; van Genderen, ME; van Rijn, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (86.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Genderen, ME | 1 |
| Jonkman, JG | 1 |
| van Rijn, M | 1 |
| Dees, A | 1 |
| Ayoub, T | 1 |
| Arshad, I | 1 |
| Donnellan, I | 1 |
| TEOKHAROV, BA | 1 |
| ANIKIN, AF | 1 |
| KLINYSHKOVA, VM | 1 |
| SZELL, I | 1 |
| EMBER, M | 1 |
| NOVAK, E | 1 |
| SOLOMKIN, M | 1 |
| EDELSTEIN, SW | 1 |
| Shelley, WB | 1 |
| Shelley, ED | 1 |
| Suriyanon, V | 1 |
| Nelson, KE | 1 |
| Choomsai na Ayudhya, V | 1 |
| Wijma, J | 1 |
| Kauer, FM | 1 |
| van Saene, HK | 1 |
| van de Wiel, HB | 1 |
| Janssens, J | 1 |
| Fox, GN | 1 |
| Berg, AO | 1 |
| Soman, MP | 1 |
| Watson, RA | 1 |
| Sokol, AB | 1 |
| Min, DS | 1 |
| Trought, VP | 1 |
| Pejtsik, B | 1 |
| Tóth, E | 1 |
2 reviews available for metronidazole and Cystitis
| Article | Year |
|---|---|
Lower genitourinary infections in women.
Topics: Amoxicillin; Anti-Infective Agents, Urinary; Cystitis; Diagnosis, Differential; Drug Combinations; F | 1986 |
Gardnerella vaginalis: genitourinary pathogen in men.
Topics: Adult; Bacteriuria; Balanitis; Child; Culture Media; Cystitis; Female; Gardnerella vaginalis; Genita | 1985 |
1 trial available for metronidazole and Cystitis
| Article | Year |
|---|---|
Antibiotics and suction drainage as prophylaxis in vaginal and abdominal hysterectomy.
Topics: Abscess; Bacteroides Infections; Cefuroxime; Cephalosporins; Cystitis; Escherichia coli Infections; | 1987 |
12 other studies available for metronidazole and Cystitis
| Article | Year |
|---|---|
Emphysematous cystitis due to recurrent Clostridium difficile infection.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Cystitis; Emphysema; | 2014 |
Concurrent emphysematous cholecystitis and emphysematous cystitis in a non-diabetic patient.
Topics: Aged, 80 and over; Anti-Infective Agents; Cefuroxime; Cystitis; Drug Therapy, Combination; Emphysema | 2009 |
[EXPERIENCE WITH PERORAL THERAPY OF UROGENITAL TRICHOMONIASIS WITH FLAGYL].
Topics: Cystitis; Female; Humans; Imidazoles; Inflammation; Intraabdominal Infections; Metronidazole; Tricho | 1963 |
[TREATMENT OF TRICHOMONAL VAGINITIS WITH IMIDAZOLE DERIVATE].
Topics: Chloramphenicol; Cystitis; Escherichia coli Infections; Female; Humans; Imidazoles; Metronidazole; N | 1963 |
METRONIDAZOLE--A REPORT OF A CLINICAL INVESTIGATION.
Topics: Azo Compounds; Biomedical Research; Cystitis; Female; Humans; Metronidazole; Sulfisoxazole; Toxicolo | 1964 |
[HUMAN UROGENITAL TRICHOMONAS INFECTION AND ITS TREATMENT].
Topics: Cystitis; Diagnosis; Drug Therapy; Female; Genitalia; Genitalia, Male; Humans; Intraabdominal Infect | 1964 |
Urinary tract infection as a cause of lichen planus: metronidazole therapy.
Topics: Cystitis; Drug Therapy, Combination; Female; Humans; Lichen Planus; Metronidazole; Middle Aged; Nitr | 1984 |
Trichomonas vaginalis in a perinephric abscess. A case report.
Topics: Abscess; Chronic Disease; Cystitis; Female; Humans; Metronidazole; Middle Aged; Perinephritis; Trich | 1975 |
Single-dose therapy for genitourinary infections.
Topics: Acute Disease; Anti-Bacterial Agents; Antifungal Agents; Candidiasis, Vulvovaginal; Cystitis; Drug A | 1987 |
Trichomonas cystitis in a six-week-old infant--effective treatment with oral metronidazole.
Topics: Administration, Oral; Cystitis; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metronid | 1972 |
Treatment for cystitis.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Cystitis; Female; Metronidazole | 1973 |
[The role of Trichomonas urogenitalis in the development of adnexitis and its treatment].
Topics: Adolescent; Cystitis; Female; Humans; Metronidazole; Oophoritis; Pelvic Inflammatory Disease; Salpin | 1969 |