metronidazole has been researched along with Cutaneous Fistula in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cutaneous Fistula: An abnormal passage or communication leading from an internal organ to the surface of the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the use of metronidazole as a prophylactic agent against pharyngocutaneous fistula (PCF) formation." | 9.15 | Pharyngocutaneous fistula complicating laryngectomy: can metronidazole help? ( Dimaka, K; Kourousis, C; Mallis, A; Margaritis, V; Mastronikolis, NS; Naxakis, SS; Panogeorgou, T; Papadas, TA; Stathas, T; Stavrou, S, 2011) |
| "To evaluate the use of metronidazole as a prophylactic agent against pharyngocutaneous fistula (PCF) formation." | 5.15 | Pharyngocutaneous fistula complicating laryngectomy: can metronidazole help? ( Dimaka, K; Kourousis, C; Mallis, A; Margaritis, V; Mastronikolis, NS; Naxakis, SS; Panogeorgou, T; Papadas, TA; Stathas, T; Stavrou, S, 2011) |
| "Appropriate treatment of perianal fistulas in Crohn's disease (CD) involves accurate anatomic evaluation." | 1.38 | Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy. ( Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stathas, T | 1 |
| Mallis, A | 1 |
| Mastronikolis, NS | 1 |
| Naxakis, SS | 1 |
| Dimaka, K | 1 |
| Panogeorgou, T | 1 |
| Stavrou, S | 1 |
| Margaritis, V | 1 |
| Kourousis, C | 1 |
| Papadas, TA | 1 |
| Scotton, W | 1 |
| Cobb, R | 1 |
| Pang, L | 1 |
| Nixon, I | 1 |
| Joshi, A | 1 |
| Jeannon, JP | 1 |
| Oakley, R | 1 |
| French, G | 1 |
| Hemsley, C | 1 |
| Simo, R | 1 |
| Lahat, A | 1 |
| Assulin, Y | 1 |
| Beer-Gabel, M | 1 |
| Chowers, Y | 1 |
| Atienza, P | 1 |
1 review available for metronidazole and Cutaneous Fistula
| Article | Year |
|---|---|
[Refractory perineal fistulas in Crohn's disease].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Diseas | 2007 |
1 trial available for metronidazole and Cutaneous Fistula
| Article | Year |
|---|---|
Pharyngocutaneous fistula complicating laryngectomy: can metronidazole help?
Topics: Aged; Anti-Infective Agents; Combined Modality Therapy; Cutaneous Fistula; Female; Humans; Incidence | 2011 |
2 other studies available for metronidazole and Cutaneous Fistula
| Article | Year |
|---|---|
Post-operative wound infection in salvage laryngectomy: does antibiotic prophylaxis have an impact?
Topics: Administration, Intravenous; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Cohort Studi | 2012 |
Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy.
Topics: Abscess; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory | 2012 |