metronidazole has been researched along with Cryptosporidiosis in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cryptosporidiosis: Intestinal infection with organisms of the genus CRYPTOSPORIDIUM. It occurs in both animals and humans. Symptoms include severe DIARRHEA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe the outcome of dietary management of canine noninfectious acute colitis with or without concurrent oral administration of metronidazole using a randomized controlled clinical trial." | 9.51 | Randomized controlled trial demonstrates nutritional management is superior to metronidazole for treatment of acute colitis in dogs. ( Bremer, CA; Cooper, E; Howard, JP; Laxalde, J; Marsh, A; Mathie, T; Parker, VJ; Perea, S; Rudinsky, AJ; Suchodolski, J; Winston, J; Yaxley, P, 2022) |
| "To describe the outcome of dietary management of canine noninfectious acute colitis with or without concurrent oral administration of metronidazole using a randomized controlled clinical trial." | 5.51 | Randomized controlled trial demonstrates nutritional management is superior to metronidazole for treatment of acute colitis in dogs. ( Bremer, CA; Cooper, E; Howard, JP; Laxalde, J; Marsh, A; Mathie, T; Parker, VJ; Perea, S; Rudinsky, AJ; Suchodolski, J; Winston, J; Yaxley, P, 2022) |
| "The high Giardia infection rates and intensities in calves of a wide age range and the clinical response to metronidazole suggest that Giardia infection contributed to the outbreaks of diarrhea." | 1.29 | Concurrent infections of Giardia and Cryptosporidium on two Ohio farms with calf diarrhea. ( Herd, RP; Rings, DM; Xiao, L, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Rudinsky, AJ | 1 |
| Parker, VJ | 1 |
| Winston, J | 1 |
| Cooper, E | 1 |
| Mathie, T | 1 |
| Howard, JP | 1 |
| Bremer, CA | 1 |
| Yaxley, P | 1 |
| Marsh, A | 1 |
| Laxalde, J | 1 |
| Suchodolski, J | 1 |
| Perea, S | 1 |
| El-Shewehy, DMM | 1 |
| Elshopakey, GE | 1 |
| Ismail, A | 1 |
| Hassan, SS | 1 |
| Ramez, AM | 1 |
| Madbouly, N | 1 |
| El Amir, A | 1 |
| Abdel Kader, A | 1 |
| Rabee, I | 1 |
| Farid, A | 1 |
| Abouel-Nour, MF | 2 |
| EL-Shewehy, DM | 2 |
| Hamada, SF | 2 |
| Morsy, TA | 2 |
| Ellis, AE | 1 |
| Brown, CA | 1 |
| Miller, DL | 1 |
| Xiao, L | 1 |
| Herd, RP | 1 |
| Rings, DM | 1 |
| Nelson, SP | 1 |
| Lin, PL | 1 |
| Miller, J | 1 |
| Katz, BZ | 1 |
| Gonzalez-Crussi, F | 1 |
| Shaio, MF | 1 |
| Hou, SC | 1 |
| Yueh, FL | 1 |
| Chang, FY | 1 |
| Chou, PT | 1 |
1 trial available for metronidazole and Cryptosporidiosis
| Article | Year |
|---|---|
Randomized controlled trial demonstrates nutritional management is superior to metronidazole for treatment of acute colitis in dogs.
Topics: Animals; Colitis; Cryptosporidiosis; Cryptosporidium; Dog Diseases; Dogs; Dysbiosis; Metronidazole; | 2022 |
8 other studies available for metronidazole and Cryptosporidiosis
| Article | Year |
|---|---|
Therapeutic Potency of Ginger, Garlic, and Pomegranate Extracts Against Cryptosporidium parvum-Mediated Gastro-Splenic Damage in Mice.
Topics: Animals; Biological Products; Cryptosporidiosis; Cryptosporidium; Cryptosporidium parvum; Garlic; Ma | 2023 |
The immunomodulatory activity of secnidazole-nitazoxanide in a murine cryptosporidiosis model.
Topics: Animals; Antiprotozoal Agents; Cryptosporidiosis; Cryptosporidium parvum; Cytokines; Disease Models, | 2021 |
THE EFFICACY OF THREE MEDICINAL PLANTS: GARLIC, GINGER AND MIRAZID AND A CHEMICAL DRUG METRONIDAZOLE AGAINST CRYPTOSPORIDIUM PARVUM. I-IMMUNOLOGICAL RESPONSE.
Topics: Animals; Coccidiostats; Commiphora; Cryptosporidiosis; Cryptosporidium parvum; Garlic; Male; Metroni | 2015 |
THE EFFICACY OF THREE MEDICINAL PLANTS; GARLIC, GINGER AND MIRAZID AND A CHEMICAL DRUG METRONIDAZOLE AGAINST CRYPTOSPORIDIUM PARVUM: II-HISTOLOGICAL CHANGES.
Topics: Animals; Antiprotozoal Agents; Commiphora; Cryptosporidiosis; Cryptosporidium parvum; Feces; Garlic; | 2016 |
Diagnostic exercise: chronic vomiting in a dog.
Topics: Animals; Antiprotozoal Agents; Biopsy; Cryptosporidiosis; Cryptosporidium; Diagnosis, Differential; | 2010 |
Concurrent infections of Giardia and Cryptosporidium on two Ohio farms with calf diarrhea.
Topics: Animals; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Outbreaks; F | 1993 |
Cryptosporidia enterocolitis in an immunocompetent infant treated with paromomycin.
Topics: Animals; Anti-Infective Agents; Biopsy; Cryptosporidiosis; Duodenum; Enterocolitis; Humans; Immunoco | 1999 |
Giardiasis coinciding with cryptosporidiosis in an immunocompetent patient with protracted watery diarrhea.
Topics: Adult; Cryptosporidiosis; Diarrhea; Giardiasis; Humans; Metronidazole | 1990 |