metronidazole has been researched along with Cross Infection in 126 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cross Infection: Any infection which a patient contracts in a health-care institution.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No association was found between metronidazole use and subsequent CDI in ICU patients who received antibiotic therapy for sepsis." | 7.81 | Risk of Clostridium difficile infection in intensive care unit patients with sepsis exposed to metronidazole. ( Czosnowski, QA; Fraimow, HS; Hunter, K; Sabbah, MA; Schorr, C; Torjman, MC; Tsigrelis, C; Zanotti, S, 2015) |
| " Since the aetiology of antibiotic-associated colitis was discovered 14 years ago, two antibiotics in particular, metronidazole and vancomycin, have been used to treat C." | 4.78 | Clostridium difficile infection: responses, relapses and re-infections. ( Spencer, RC; Wilcox, MH, 1992) |
| "The objectives were to determine the risk factors for recurrent healthcare facility-associated Clostridioides difficile infection (HCF-CDI) in a high CDI incidence, low antibiotic use setting and to determine if length of cefotaxime exposure is a risk factor for recurrent HCF-CDI." | 4.31 | Risk factors for recurrent healthcare-facility associated Clostridioides difficile infection in a Swedish setting. ( Edman-Wallér, J; Jacobsson, G; Karp, J; Toepfer, M, 2023) |
| "08% metronidazole (MDE) influencing the microbiologic epidemiology and incidence of nonintubation pneumonia (NIP) and ventilator-associated pneumonia (VAP)." | 3.83 | Prospective observational study to compare oral topical metronidazole versus 0.2% chlorhexidine gluconate to prevent nosocomial pneumonia. ( Chen, EZ; Chen, Y; Jing, F; Mao, EQ; Sheng, HQ; Wang, XF; Yang, YJ; Yang, ZT; Zhao, SY; Zhu, C, 2016) |
| "No association was found between metronidazole use and subsequent CDI in ICU patients who received antibiotic therapy for sepsis." | 3.81 | Risk of Clostridium difficile infection in intensive care unit patients with sepsis exposed to metronidazole. ( Czosnowski, QA; Fraimow, HS; Hunter, K; Sabbah, MA; Schorr, C; Torjman, MC; Tsigrelis, C; Zanotti, S, 2015) |
| "20 percent of the patients have recurrence after metronidazole or vancomycin treatment, and each recurrence increases the chance of a further one." | 2.49 | [Clostridium difficile infection: epidemiology, disease burden and therapy]. ( Baji, P; Banai, J; Brodszky, V; Gulácsi, L; Kertész, A; Kopcsóné Németh, I; Ludwig, E; Péntek, M; Prinz, G; Reményi, P; Strbák, B; Zsoldiné Urbán, E, 2013) |
| "Relapse is frequent and must be distinguished from reinfection." | 2.45 | [Clostridium-difficile-associated diarrhea]. ( Bujanda, L; Cosme, A, 2009) |
| "However, if the first recurrence is characterized as severe, vancomycin should be used." | 2.45 | Recurrent Clostridium difficile infection: a review of risk factors, treatments, and outcomes. ( Johnson, S, 2009) |
| "Rarely, pseudomembranous colitis, a severe complication of CDAD, must be treated through surgical intervention." | 2.44 | Current and future treatment modalities for Clostridium difficile-associated disease. ( Halsey, J, 2008) |
| "Pseudomembranous colitis is commonly associated with the use of antibiotics but may follow administration of other drugs and has occurred in patients who have not received any medication." | 2.39 | Antibiotic-induced diarrhea and pseudomembranous colitis. ( Jacobs, NF, 1994) |
| "Several new approaches to treatment of pneumonia in the critical care setting are being evaluated, including single-agent empiric coverage using a broad-spectrum beta-lactam agent; broad-spectrum quinolones, such as ciprofloxacin; intrabronchial aminoglycoside instillation therapy; and passive immune therapy with immunoglobulins and monoclonal antibodies." | 2.38 | Approach to therapy of respiratory infections in the critical care setting. ( Pennington, JE, 1990) |
| "Oral treatment with metronidazole or vancomycin is recommended, but there is a major problem with symptomatic recurrence after treatment." | 1.48 | The 'ins and outs' of faecal microbiota transplant for recurrent Clostridium difficile diarrhoea at Wits Donald Gordon Medical Centre, Johannesburg, South Africa. ( Drennan, K; Fabian, J; Gaylard, PC; Hepple, A; Karlsson, K; Lee, S; Lowman, W; McNamara, L; Simons, G, 2018) |
| "Adults with hematological malignancies are at high-risk of Clostridium difficile infection (CDI), but no guidelines for CDI treatment are available in this population." | 1.46 | Treating Clostridium difficile infection in patients presenting with hematological malignancies: Are current guidelines applicable? ( Boyle, E; Galperine, T; Guery, B; Héquette-Ruz, R; Herbaux, C; Robin, C, 2017) |
| "Metronidazole is an effective treatment for CDI." | 1.40 | Risk of Clostridium difficile infection in hospitalized patients receiving metronidazole for a non-C difficile infection. ( Cardona, L; Castro-Pavia, F; Hernandez, MB; Rodriguez, S; Schneider, A; Tarchini, G; Vatanchi, M; Zaleski, M, 2014) |
| "Clostridium difficile infection is considered a major cause of nosocomial diarrhoea in developed countries and is increasingly becoming more important as an etiologic agent of community diarrhoea, also in patients without risk factors." | 1.40 | [Epidemiology of Clostridium difficile-associated disease (CDAD) in Salamanca]. ( Calvo-García, N; de Frutos-Serna, M; García-Sánchez, JE; Hernández-Egido, S; María-Blázquez, A; Siller-Ruiz, M, 2014) |
| "Patients with one or more recurrence were included in this study." | 1.40 | Healthcare resource utilization for recurrent Clostridium difficile infection in a large university hospital in Houston, Texas. ( Aitken, SL; DuPont, HL; Garey, KW; Joseph, TB; Lasco, TM; Palmer, HR; Shah, DN; Xie, Y, 2014) |
| "difficile infection in subjects with type 2 diabetes mellitus admitted into acute medical wards." | 1.39 | Hospital-acquired Clostridium difficile infection among patients with type 2 diabetes mellitus in acute medical wards. ( Hassan, SA; Huda, N; Lee, YY; Rahman, RA; Wan Bebakar, WM, 2013) |
| "CDAD recurrence rates were similar to those reported in the literature." | 1.39 | Predictors of first recurrence in Clostridium difficile-associated disease. A study of 306 patients hospitalized in a Romanian tertiary referral center. ( Cioara, A; Filipescu, I; Flonta, M; Lupse, M; Todor, N, 2013) |
| "The incidence and severity of Clostridium difficile infections (CDI) have increased in Western countries." | 1.39 | Incidence and clinical features of Clostridium difficile infection in Korea: a nationwide study. ( Cheon, JH; Choi, CH; Eun, CS; Han, DS; Huh, KC; Jang, BI; Jung, SA; Kim, HS; Kim, JS; Kim, WH; Kim, YH; Kim, YS; Lee, KM; Lee, SH; Park, YS; Shin, SJ; Song, HJ; Yang, SK; Ye, BD, 2013) |
| "As data from Clostridium difficile infection (CDI) in intensive care unit (ICU) are still scarce, our objectives were to assess the morbidity and mortality of ICU-acquired CDI." | 1.38 | Outcome of ICU patients with Clostridium difficile infection. ( Adrie, C; Français, A; Garrouste-Orgeas, M; Laupland, K; Le-Monnier, A; Nguile-Makao, M; Schwebel, C; Tabah, A; Timsit, JF; Vesin, A; Zahar, JR, 2012) |
| "Metronidazole was the initial therapeutic regimen for 83 (96." | 1.36 | Clostridium difficile infection at a medical center in southern Taiwan: incidence, clinical features and prognosis. ( Chang, CM; Chen, PL; Chung, CH; Hung, YP; Ko, WC; Lee, CC; Lee, HC; Lee, NY; Wu, CJ; Yan, JJ, 2010) |
| "Since 2002, an epidemic of Clostridium difficile infections has occurred in southern Quebec, Canada." | 1.35 | Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain. ( Béliveau, C; Labbé, AC; Laverdière, M; Louie, T; Maccannell, D; Pépin, J; Poirier, L; Savoie, M, 2008) |
| "Surgical site infections are significantly and independently associated with LOS and cost and contribute to inpatient morbidity and expense." | 1.35 | Impact of surgical site infections on length of stay and costs in selected colorectal procedures. ( Mahmoud, NN; Saunders, WB; Turpin, RS; Yang, G, 2009) |
| "Metronidazole resistance was estimated to be 35." | 1.31 | Evolution of metronidazole and tetracycline susceptibility pattern in Helicobacter pylori at a hospital in Saudi Arabia. ( Al-Quorain, AA; Al-Qurashi, AR; El-Morsy, F, 2001) |
| "Oral metronidazole was the treatment for 632 (70%) of 908 patients (1% intolerance, 2% failure, 7% relapse) and oral vancomycin was given to 122 (13%) of 908 patients (1% intolerance, 1% failure, 10% relapse)." | 1.29 | Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991. ( Gerding, DN; Lee, JT; Olson, MM; Shanholtzer, CJ, 1994) |
| " The virtual peak levels which had been determined by pharmacokinetic dosage calculation were compared with the serum concentrations obtained directly after the administration as well as after 15, 30, 60 and 180 min." | 1.29 | Studies on drug monitoring in thrice and once daily treatment with aminoglycosides. ( Georgieff, M; Konrad, F; Neumeister, B; Rommel, H; Wagner, R, 1993) |
| "Vancomycin resistance was not an independent predictor of death, and its role was difficult to establish, because cohort patients were among the most severely ill of all hospitalized patients." | 1.29 | Risk factors for mortality associated with enterococcal bloodstream infections. ( Culver, D; Danzing, L; Edwards, J; Gaynes, R; Stroud, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.97) | 18.7374 |
| 1990's | 19 (15.08) | 18.2507 |
| 2000's | 38 (30.16) | 29.6817 |
| 2010's | 58 (46.03) | 24.3611 |
| 2020's | 6 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Labbé, AC | 1 |
| Poirier, L | 1 |
| Maccannell, D | 1 |
| Louie, T | 1 |
| Savoie, M | 1 |
| Béliveau, C | 1 |
| Laverdière, M | 1 |
| Pépin, J | 2 |
| Liu, CY | 1 |
| Huang, YT | 1 |
| Liao, CH | 1 |
| Yen, LC | 1 |
| Lin, HY | 1 |
| Hsueh, PR | 1 |
| Karlowsky, JA | 1 |
| Laing, NM | 1 |
| Zhanel, GG | 1 |
| Alauzet, C | 1 |
| Mory, F | 1 |
| Teyssier, C | 1 |
| Hallage, H | 1 |
| Carlier, JP | 1 |
| Grollier, G | 1 |
| Lozniewski, A | 1 |
| Wu, Y | 1 |
| Wang, YY | 1 |
| Bai, LL | 1 |
| Zhang, WZ | 1 |
| Li, GW | 1 |
| Lu, JX | 1 |
| Karp, J | 1 |
| Edman-Wallér, J | 1 |
| Toepfer, M | 1 |
| Jacobsson, G | 1 |
| Dai, W | 1 |
| Yang, T | 1 |
| Yan, L | 1 |
| Niu, S | 1 |
| Zhang, C | 1 |
| Sun, J | 1 |
| Wang, Z | 1 |
| Xia, Y | 1 |
| Phanchana, M | 1 |
| Phetruen, T | 1 |
| Harnvoravongchai, P | 1 |
| Raksat, P | 1 |
| Ounjai, P | 1 |
| Chankhamhaengdecha, S | 1 |
| Janvilisri, T | 1 |
| Sugimoto, H | 1 |
| Yoshihara, A | 1 |
| Yamamoto, T | 1 |
| Sugimoto, K | 1 |
| Nicholas, A | 1 |
| Kim, YK | 1 |
| Lee, WK | 1 |
| Selasi, GN | 1 |
| Na, SH | 1 |
| Kwon, HI | 1 |
| Kim, YJ | 1 |
| Lee, HS | 1 |
| Song, KE | 1 |
| Shin, JH | 1 |
| Lee, JC | 1 |
| Psoinos, CM | 1 |
| Collins, CE | 1 |
| Ayturk, MD | 1 |
| Anderson, FA | 1 |
| Santry, HP | 1 |
| Robin, C | 1 |
| Héquette-Ruz, R | 1 |
| Guery, B | 1 |
| Boyle, E | 1 |
| Herbaux, C | 1 |
| Galperine, T | 1 |
| Aberkane, S | 1 |
| Pradel, B | 1 |
| Dumont, Y | 1 |
| Veloo, ACM | 1 |
| Laurens, C | 1 |
| Bonzon, L | 1 |
| Godreuil, S | 1 |
| Marchandin, H | 1 |
| Jean-Pierre, H | 1 |
| Bishop, EJ | 1 |
| Tiruvoipati, R | 1 |
| Metcalfe, J | 1 |
| Marshall, C | 1 |
| Botha, J | 1 |
| Kelley, PG | 1 |
| Goyal, H | 1 |
| Perisetti, A | 1 |
| Rehman, MR | 1 |
| Singla, U | 1 |
| Lee, S | 1 |
| Drennan, K | 1 |
| Simons, G | 1 |
| Hepple, A | 1 |
| Karlsson, K | 1 |
| Lowman, W | 1 |
| Gaylard, PC | 1 |
| McNamara, L | 1 |
| Fabian, J | 1 |
| Katz, KC | 1 |
| Golding, GR | 1 |
| Choi, KB | 1 |
| Pelude, L | 1 |
| Amaratunga, KR | 1 |
| Taljaard, M | 1 |
| Alexandre, S | 1 |
| Collet, JC | 1 |
| Davis, I | 1 |
| Du, T | 1 |
| Evans, GA | 1 |
| Frenette, C | 1 |
| Gravel, D | 1 |
| Hota, S | 1 |
| Kibsey, P | 1 |
| Langley, JM | 1 |
| Lee, BE | 1 |
| Lemieux, C | 1 |
| Longtin, Y | 1 |
| Mertz, D | 1 |
| Mieusement, LMD | 1 |
| Minion, J | 1 |
| Moore, DL | 1 |
| Mulvey, MR | 1 |
| Richardson, S | 1 |
| Science, M | 1 |
| Simor, AE | 3 |
| Stagg, P | 1 |
| Suh, KN | 1 |
| Taylor, G | 1 |
| Wong, A | 1 |
| Thampi, N | 1 |
| Kodadek, LM | 1 |
| Lipsett, PA | 1 |
| Calaway, AC | 1 |
| Jacob, JM | 1 |
| Tong, Y | 1 |
| Shumaker, L | 1 |
| Kitley, W | 1 |
| Boris, RS | 1 |
| Cary, C | 1 |
| Kaimakliotis, H | 1 |
| Masterson, TA | 1 |
| Bihrle, R | 1 |
| Koch, MO | 1 |
| Sedigh Ebrahim-Saraie, H | 1 |
| Heidari, H | 1 |
| Amanati, A | 1 |
| Bazargani, A | 1 |
| Alireza Taghavi, S | 1 |
| Nikokar, I | 1 |
| Kalantar, K | 1 |
| Motamedifar, M | 1 |
| Kazakova, SV | 1 |
| Baggs, J | 1 |
| McDonald, LC | 1 |
| Yi, SH | 1 |
| Hatfield, KM | 1 |
| Guh, A | 1 |
| Reddy, SC | 1 |
| Jernigan, JA | 1 |
| Kimura, T | 1 |
| Snijder, R | 1 |
| Sugitani, T | 1 |
| Goret, NE | 1 |
| Goret, CC | 1 |
| Alvarez, AM | 1 |
| Rathore, MH | 1 |
| Debast, SB | 1 |
| Bauer, MP | 1 |
| Sanders, IM | 1 |
| Wilcox, MH | 3 |
| Kuijper, EJ | 1 |
| Surawicz, CM | 2 |
| Brandt, LJ | 2 |
| Binion, DG | 1 |
| Ananthakrishnan, AN | 1 |
| Curry, SR | 1 |
| Gilligan, PH | 1 |
| McFarland, LV | 2 |
| Mellow, M | 1 |
| Zuckerbraun, BS | 1 |
| Strauss, R | 1 |
| Neurath, MF | 1 |
| Brodszky, V | 2 |
| Gulácsi, L | 2 |
| Ludwig, E | 2 |
| Prinz, G | 2 |
| Banai, J | 2 |
| Reményi, P | 2 |
| Strbák, B | 2 |
| Kertész, A | 2 |
| Kopcsóné Németh, I | 2 |
| Zsoldiné Urbán, E | 2 |
| Baji, P | 2 |
| Péntek, M | 2 |
| Hassan, SA | 1 |
| Rahman, RA | 1 |
| Huda, N | 1 |
| Wan Bebakar, WM | 1 |
| Lee, YY | 1 |
| Ebigbo, A | 1 |
| Messmann, H | 1 |
| Keller, JM | 1 |
| Lupse, M | 1 |
| Flonta, M | 1 |
| Cioara, A | 1 |
| Filipescu, I | 1 |
| Todor, N | 1 |
| Rodriguez, S | 1 |
| Hernandez, MB | 1 |
| Tarchini, G | 1 |
| Zaleski, M | 1 |
| Vatanchi, M | 1 |
| Cardona, L | 1 |
| Castro-Pavia, F | 1 |
| Schneider, A | 1 |
| DuPont, HL | 2 |
| Siller-Ruiz, M | 1 |
| Calvo-García, N | 1 |
| Hernández-Egido, S | 1 |
| María-Blázquez, A | 1 |
| de Frutos-Serna, M | 1 |
| García-Sánchez, JE | 1 |
| Aitken, SL | 1 |
| Joseph, TB | 1 |
| Shah, DN | 1 |
| Lasco, TM | 1 |
| Palmer, HR | 1 |
| Xie, Y | 1 |
| Garey, KW | 1 |
| Herzog, T | 1 |
| Deleites, C | 1 |
| Belyaev, O | 1 |
| Chromik, AM | 1 |
| Uhl, W | 1 |
| Sabbah, MA | 1 |
| Schorr, C | 1 |
| Czosnowski, QA | 1 |
| Hunter, K | 1 |
| Torjman, MC | 1 |
| Fraimow, HS | 1 |
| Zanotti, S | 1 |
| Tsigrelis, C | 1 |
| Biswas, JS | 1 |
| Patel, A | 1 |
| Otter, JA | 1 |
| Wade, P | 1 |
| Newsholme, W | 1 |
| van Kleef, E | 1 |
| Goldenberg, SD | 1 |
| Khanafer, N | 1 |
| Blais, L | 1 |
| Barbut, F | 1 |
| Hirschel, B | 1 |
| Vanhems, P | 1 |
| Falcone, M | 1 |
| Russo, A | 1 |
| Iraci, F | 1 |
| Carfagna, P | 1 |
| Goldoni, P | 1 |
| Vullo, V | 1 |
| Venditti, M | 1 |
| Chen, Y | 1 |
| Mao, EQ | 1 |
| Yang, YJ | 1 |
| Zhao, SY | 1 |
| Zhu, C | 1 |
| Wang, XF | 1 |
| Jing, F | 1 |
| Sheng, HQ | 1 |
| Yang, ZT | 1 |
| Chen, EZ | 1 |
| Peretz, A | 1 |
| Tkhawkho, L | 1 |
| Pastukh, N | 1 |
| Brodsky, D | 1 |
| Halevi, CN | 1 |
| Nitzan, O | 1 |
| Miller-Roll, T | 1 |
| Na'amnih, W | 1 |
| Cohen, D | 1 |
| Carmeli, Y | 1 |
| Adler, A | 1 |
| Truong, CY | 1 |
| Gombar, S | 1 |
| Wilson, R | 1 |
| Sundararajan, G | 1 |
| Tekic, N | 1 |
| Holubar, M | 1 |
| Shepard, J | 1 |
| Madison, A | 1 |
| Tompkins, L | 1 |
| Shah, N | 1 |
| Deresinski, S | 1 |
| Schroeder, LF | 1 |
| Banaei, N | 1 |
| Cipriano Souza, R | 1 |
| Vicente, AC | 1 |
| Vieira, VV | 1 |
| Marques, SG | 1 |
| Soares, Md | 1 |
| Moura, MC | 1 |
| Koifman, RJ | 1 |
| Weber, WP | 1 |
| Marti, WR | 1 |
| Zwahlen, M | 1 |
| Misteli, H | 1 |
| Rosenthal, R | 1 |
| Reck, S | 1 |
| Fueglistaler, P | 1 |
| Bolli, M | 1 |
| Trampuz, A | 1 |
| Oertli, D | 1 |
| Widmer, AF | 1 |
| Calfee, DP | 1 |
| Balassiano, IT | 1 |
| Miranda, KR | 1 |
| Boente, RF | 1 |
| Pauer, H | 1 |
| Oliveira, IC | 1 |
| Santos-Filho, J | 1 |
| Amorim, EL | 1 |
| Caniné, GA | 1 |
| Souza, CF | 1 |
| Gomes, MZ | 1 |
| Ferreira, EO | 1 |
| Brazier, JS | 1 |
| Domingues, RM | 1 |
| Bujanda, L | 1 |
| Cosme, A | 1 |
| Johnson, S | 2 |
| Riddle, DJ | 1 |
| Dubberke, ER | 1 |
| Byun, TJ | 1 |
| Han, DS | 2 |
| Ahn, SB | 1 |
| Cho, HS | 1 |
| Kim, TY | 1 |
| Eun, CS | 2 |
| Jeon, YC | 1 |
| Sohn, JH | 1 |
| Kang, JO | 1 |
| Mahmoud, NN | 1 |
| Turpin, RS | 1 |
| Yang, G | 1 |
| Saunders, WB | 1 |
| Schmiedeskamp, M | 1 |
| Harpe, S | 1 |
| Polk, R | 1 |
| Oinonen, M | 2 |
| Pakyz, A | 2 |
| Parks, T | 1 |
| Wallis, S | 1 |
| Wilson, J | 1 |
| Gkrania-Klotsas, E | 1 |
| Nicholl, C | 1 |
| Chung, CH | 1 |
| Wu, CJ | 1 |
| Lee, HC | 1 |
| Yan, JJ | 1 |
| Chang, CM | 1 |
| Lee, NY | 1 |
| Chen, PL | 1 |
| Lee, CC | 1 |
| Hung, YP | 1 |
| Ko, WC | 1 |
| Pakyz, AL | 1 |
| Carroll, NV | 1 |
| Harpe, SE | 1 |
| Polk, RE | 1 |
| Salkind, AR | 1 |
| Kvaran, RB | 1 |
| Valsdóttir, EB | 1 |
| Sigurdsson, HK | 1 |
| Gottfredsson, M | 1 |
| Stevens, V | 1 |
| Dumyati, G | 1 |
| Fine, LS | 1 |
| Fisher, SG | 1 |
| van Wijngaarden, E | 1 |
| Altın, C | 1 |
| Kanyılmaz, S | 1 |
| Baysal, S | 1 |
| Özin, B | 1 |
| Cocanour, CS | 1 |
| Rajendran, R | 1 |
| Sreekumar, S | 2 |
| Sudhakar, A | 1 |
| Gardner, E | 1 |
| Meghani, N | 1 |
| Mancuso, P | 1 |
| Thomson, A | 1 |
| Toprak, NU | 1 |
| Uzunkaya, OD | 1 |
| Sóki, J | 1 |
| Soyletir, G | 1 |
| Malkan, AD | 1 |
| Scholand, SJ | 1 |
| Lee, YC | 1 |
| Wang, JT | 1 |
| Chen, AC | 1 |
| Sheng, WH | 1 |
| Chang, SC | 1 |
| Chen, YC | 1 |
| Kelly, CP | 2 |
| Peiseler, GJ | 1 |
| Armbruster, S | 1 |
| Goldkind, L | 1 |
| Kim, YS | 1 |
| Kim, YH | 1 |
| Kim, WH | 1 |
| Kim, JS | 1 |
| Kim, HS | 2 |
| Park, YS | 1 |
| Song, HJ | 1 |
| Shin, SJ | 1 |
| Yang, SK | 1 |
| Ye, BD | 1 |
| Lee, KM | 1 |
| Lee, SH | 1 |
| Jang, BI | 1 |
| Jung, SA | 1 |
| Cheon, JH | 1 |
| Choi, CH | 1 |
| Huh, KC | 1 |
| Münchhoff, M | 1 |
| Strube, H | 1 |
| Wagener, J | 1 |
| Bogner, JR | 1 |
| Zahar, JR | 1 |
| Schwebel, C | 1 |
| Adrie, C | 1 |
| Garrouste-Orgeas, M | 1 |
| Français, A | 1 |
| Vesin, A | 1 |
| Nguile-Makao, M | 1 |
| Tabah, A | 1 |
| Laupland, K | 1 |
| Le-Monnier, A | 1 |
| Timsit, JF | 1 |
| Cordero-Laurent, E | 1 |
| Rodríguez, C | 1 |
| Rodríguez-Cavallini, E | 1 |
| Gamboa-Coronado, MM | 1 |
| Quesada-Gómez, C | 1 |
| Malnick, SD | 1 |
| Zimhony, O | 1 |
| PEREYRA, AJ | 1 |
| LANSING, JD | 1 |
| Bartoloni, A | 1 |
| Mantella, A | 1 |
| Goldstein, BP | 1 |
| Dei, R | 1 |
| Benedetti, M | 1 |
| Sbaragli, S | 1 |
| Paradisi, F | 1 |
| Poutanen, SM | 1 |
| Valiquette, L | 1 |
| Alary, ME | 1 |
| Villemure, P | 1 |
| Pelletier, A | 1 |
| Forget, K | 1 |
| Pépin, K | 1 |
| Chouinard, D | 1 |
| Bouza, E | 2 |
| Muñoz, P | 2 |
| Alonso, R | 1 |
| Aslam, S | 1 |
| Hamill, RJ | 1 |
| Musher, DM | 1 |
| Freeman, J | 1 |
| Stott, J | 1 |
| Baines, SD | 1 |
| Fawley, WN | 1 |
| Cherifi, S | 1 |
| Delmee, M | 1 |
| Van Broeck, J | 1 |
| Beyer, I | 1 |
| Byl, B | 1 |
| Mascart, G | 1 |
| Scicluna, EA | 1 |
| Haider, J | 1 |
| Borg, MA | 1 |
| Cuschieri, P | 1 |
| Burillo, A | 1 |
| Pareja Sierra, T | 1 |
| Hornillos Calvo, M | 1 |
| Marra, AR | 1 |
| Edmond, MB | 1 |
| Wenzel, RP | 1 |
| Bearman, GM | 1 |
| Blix, HS | 1 |
| Røed, J | 1 |
| Sti, MO | 1 |
| Iakovlev, SV | 1 |
| Beloborodov, VB | 1 |
| Sidorenko, SV | 1 |
| Iakovlev, VP | 1 |
| Grigor'ev, KB | 1 |
| Eliseeva, EV | 1 |
| Kon, EM | 1 |
| Levit, AL | 1 |
| Kostina, GV | 1 |
| Kuprenkov, AV | 1 |
| Mukhacheva, SIu | 1 |
| Saturnov, AV | 1 |
| Sergeev, IN | 1 |
| Spasov, GP | 1 |
| Stakanov, AV | 1 |
| Ushakova, MA | 1 |
| Pupaibool, J | 1 |
| Khantipong, M | 1 |
| Suankratay, C | 1 |
| Halsey, J | 1 |
| Scheurer, D | 1 |
| Al-Nassir, WN | 1 |
| Sethi, AK | 1 |
| Li, Y | 1 |
| Pultz, MJ | 1 |
| Riggs, MM | 1 |
| Donskey, CJ | 1 |
| Olson, MM | 1 |
| Shanholtzer, CJ | 1 |
| Lee, JT | 1 |
| Gerding, DN | 2 |
| Demling, L | 1 |
| Stoll, R | 1 |
| Jobe, BA | 1 |
| Grasley, A | 1 |
| Deveney, KE | 1 |
| Deveney, CW | 1 |
| Sheppard, BC | 1 |
| Cartmill, TD | 1 |
| Panigrahi, H | 1 |
| Worsley, MA | 1 |
| McCann, DC | 1 |
| Nice, CN | 1 |
| Keith, E | 1 |
| Schweizer, W | 1 |
| Striffeler, H | 1 |
| Lüdi, D | 1 |
| Fröscher, R | 1 |
| Hutt, D | 1 |
| Jacobs, NF | 1 |
| Vautrin, AC | 1 |
| Enck, S | 1 |
| Antoniotti, G | 1 |
| Sedallian, A | 1 |
| Odelin, MF | 1 |
| Dorche, G | 1 |
| Aubert, G | 1 |
| Konrad, F | 1 |
| Wagner, R | 1 |
| Neumeister, B | 1 |
| Rommel, H | 1 |
| Georgieff, M | 1 |
| Stroud, L | 1 |
| Edwards, J | 1 |
| Danzing, L | 1 |
| Culver, D | 1 |
| Gaynes, R | 1 |
| Redding, PJ | 1 |
| Taylor, A | 1 |
| Smith, AM | 1 |
| Richards, GA | 1 |
| Hunter, MP | 1 |
| Kasperk, R | 1 |
| Riesener, KP | 1 |
| Schumpelick, V | 1 |
| Lucas, GM | 1 |
| Lechtzin, N | 1 |
| Puryear, DW | 1 |
| Yau, LL | 1 |
| Flexner, CW | 1 |
| Moore, RD | 1 |
| Kosche, KA | 1 |
| Greenwald, DA | 1 |
| Berkman, D | 1 |
| Al-Qurashi, AR | 1 |
| El-Morsy, F | 1 |
| Al-Quorain, AA | 1 |
| Gorschlüter, M | 1 |
| Glasmacher, A | 1 |
| Hahn, C | 1 |
| Schakowski, F | 1 |
| Ziske, C | 1 |
| Molitor, E | 1 |
| Marklein, G | 1 |
| Sauerbruch, T | 1 |
| Schmidt-Wolf, IG | 1 |
| Kyne, L | 1 |
| Farrell, RJ | 1 |
| Toro, C | 1 |
| García-Samaniego, J | 1 |
| Carbó, J | 1 |
| Iñiguez, A | 1 |
| Alarcón, T | 1 |
| López-Brea, M | 1 |
| Baquero, M | 1 |
| Leroi, MJ | 1 |
| Siarakas, S | 1 |
| Gottlieb, T | 1 |
| Homann, SR | 1 |
| Bettin, KM | 1 |
| Quick, JN | 1 |
| Clabots, CR | 1 |
| Peterson, LR | 1 |
| Spencer, RC | 1 |
| Tetteroo, GW | 1 |
| Wagenvoort, JH | 1 |
| Castelein, A | 1 |
| Tilanus, HW | 1 |
| Ince, C | 1 |
| Bruining, HA | 1 |
| Pennington, JE | 1 |
| Foulke, GE | 1 |
| Silva, J | 1 |
| de Louvois, J | 1 |
| Schwigon, CD | 1 |
| Hulla, FW | 1 |
| Schulze, B | 1 |
| Maslak, A | 1 |
| Opferkuch, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Washed Microbiota Transplantation for The Treatment of Oncotherapy-Related Intestinal Complications[NCT04721041] | 40 participants (Anticipated) | Interventional | 2020-10-16 | Recruiting | |||
| Assessment Of Changes In Gut Microbiota Of Patients With Recurrent Clostridioides Difficile Infection After Fecal Microbiota Transplantation: Prospective Study[NCT05739825] | 20 participants (Anticipated) | Observational | 2023-02-13 | Recruiting | |||
| Secondary Prophylaxis With Oral Vancomycin for Clostridium Difficile Recurrence: A Randomized Control Study[NCT03200093] | Phase 4 | 65 participants (Actual) | Interventional | 2017-06-08 | Terminated (stopped due to Low recruitment due to few eligible participants.) | ||
| Fecal Calprotectin Level in Differentiating Between Inflammatory and Non-inflammatory Diarrhea in Patients With Nosocomial Diarrhea[NCT04491799] | 135 participants (Actual) | Observational | 2019-02-01 | Completed | |||
| Fecal Microbiota Transplantation Versus Standard Medical Therapy for Initial Treatment of Recurrent Clostridium Difficile Infection[NCT02255305] | Phase 2 | 6 participants (Actual) | Interventional | 2015-01-31 | Terminated (stopped due to Due to personnel issues for finding and enrolling patients, performing appropriate follow-up and performing FMT procedure) | ||
| Prospective, Randomized Study of Oral Metronidazole vs. Oral Metronidazole and Rifampin for Treatment of Clostridium Difficile-associated Diarrhea (CDAD)[NCT00182429] | Phase 3 | 100 participants | Interventional | 2004-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patients' length of stay post-procedure will be measured (NCT02255305)
Timeframe: 90 days
| Intervention | days (Mean) |
|---|---|
| FMT Group (Intervention Arm) | 22 |
| Antimicrobial Group (Control Arm) | 6.5 |
Number of patients who died from any cause within 90 days of randomization (NCT02255305)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| FMT Group (Intervention Arm) | 0 |
| Antimicrobial Group (Control Arm) | 0 |
Number of patients with resolution of diarrhea and other abdominal symptoms or return to baseline symptoms that were present prior to C. difficile diagnosis (NCT02255305)
Timeframe: 90 days
| Intervention | Participants (Count of Participants) |
|---|---|
| FMT Group (Intervention Arm) | 1 |
| Antimicrobial Group (Control Arm) | 0 |
Number of patients re-admitted to the hospital for recurrent Clostridium difficile infection (NCT02255305)
Timeframe: 90 days
| Intervention | participants (Number) |
|---|---|
| FMT Group (Intervention Arm) | 1 |
| Antimicrobial Group (Control Arm) | 1 |
Amount of time it takes for patient to have cessation of diarrhea and abdominal pain/gastrointestinal symptoms (or return to baseline) and normalization of white blood cell count, creatinine, and temperature. (NCT02255305)
Timeframe: 90 days
| Intervention | days (Number) |
|---|---|
| FMT Group (Intervention Arm) | 44 |
30 reviews available for metronidazole and Cross Infection
| Article | Year |
|---|---|
A narrative review of Clostridioides difficile infection in China.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; China; Clostridioides difficile; Clostridium Infection | 2022 |
New and emerging therapies in treatment of Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Fecal Micr | 2018 |
Prevention and Treatment of Clostridium difficile Enterocolitis.
Topics: Clostridioides difficile; Colectomy; Cross Infection; Drug Therapy, Combination; Enterocolitis, Pseu | 2018 |
Splenic abscess is extremely rare after amoebic dysentery. A case report and review of the literature.
Topics: Abscess; Adult; Amebicides; Anti-Bacterial Agents; Bacteremia; Combined Modality Therapy; Cross Infe | 2019 |
Clostridium difficile Infection in Children.
Topics: Age Factors; Anti-Infective Agents; Child; Child, Preschool; Clostridioides difficile; Clostridium I | 2019 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2013 |
[Antimicrobial therapy of Clostridium difficile infection. Systematic review and meta-analysis of the scientific evidence].
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enteroc | 2013 |
[Clostridium difficile infection: epidemiology, disease burden and therapy].
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Cost | 2013 |
Clostridium difficile infection in the elderly.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diar | 2014 |
Clostridium difficile: a reemerging pathogen.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Communicable Diseases, Emerging; C | 2008 |
[Clostridium-difficile-associated diarrhea].
Topics: Aged; Anti-Bacterial Agents; Bacterial Toxins; Biological Therapy; Clostridioides difficile; Colecto | 2009 |
Recurrent Clostridium difficile infection: a review of risk factors, treatments, and outcomes.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Diarrhea; Entero | 2009 |
Clostridium difficile infection in the intensive care unit.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomem | 2009 |
Diagnosis, management, and prevention of Clostridium difficile infection in long-term care facilities: a review.
Topics: Aged; Anti-Infective Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pse | 2010 |
Clostridium difficile: an update for the primary care clinician.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomem | 2010 |
Best strategies in recurrent or persistent Clostridium difficile infection.
Topics: Anti-Infective Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Humans; Me | 2011 |
Current strategies for management of initial Clostridium difficile infection.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enter | 2012 |
Treatment of Clostridium difficile-associated diarrhea.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Drug Administration Sche | 2002 |
Clostridium difficile-associated diarrhea in adults.
Topics: Anti-Infective Agents; Bacterial Typing Techniques; Canada; Carrier State; Clostridioides difficile; | 2004 |
Alternative treatments for Clostridium difficile disease: what really works?
Topics: Anti-Infective Agents; Carrier State; Clostridioides difficile; Clostridium Infections; Colitis; Com | 2005 |
Clinical manifestations, treatment and control of infections caused by Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; | 2005 |
Treatment of Clostridium difficile-associated disease: old therapies and new strategies.
Topics: Anti-Infective Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Enterocolitis, P | 2005 |
Antimicrobial therapy of Clostridium difficile-associated diarrhea.
Topics: Aged; Anti-Infective Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostri | 2006 |
Current and future treatment modalities for Clostridium difficile-associated disease.
Topics: Anti-Bacterial Agents; Bacterial Vaccines; Clostridioides difficile; Clostridium Infections; Cross I | 2008 |
Antibiotic-induced diarrhea and pseudomembranous colitis.
Topics: Administration, Oral; Anti-Bacterial Agents; Cluster Analysis; Cross Infection; Cytotoxins; Diarrhea | 1994 |
Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; | 2001 |
Clostridium difficile infection: responses, relapses and re-infections.
Topics: Clinical Trials as Topic; Cross Infection; Disease Outbreaks; Enterocolitis, Pseudomembranous; Human | 1992 |
Approach to therapy of respiratory infections in the critical care setting.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Ciprofloxacin; Cross Infection; Humans; Inte | 1990 |
Necrotising enterocolitis.
Topics: Age Factors; Animals; Anti-Bacterial Agents; Bacterial Infections; Bottle Feeding; Cross Infection; | 1986 |
[Classification, diagnosis and therapy of pneumonia].
Topics: Aminoglycosides; Amoxicillin; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Specificity; Bi | 1985 |
7 trials available for metronidazole and Cross Infection
| Article | Year |
|---|---|
A Prospective Program to Reduce the Clinical Incidence of Clostridium difficile Colitis Infection after Cystectomy.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Asymptomatic Diseases; Clostridioides difficile | 2019 |
[Challenges of Clostridium difficile infection].
Topics: Aminoglycosides; Biodiversity; Cause of Death; Colonoscopy; Cross Infection; Disinfection; Enterocol | 2013 |
Reduction in Clostridium difficile environmental contamination by hospitalized patients treated with fidaxomicin.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cro | 2015 |
[Multicentre study of comparative efficacy of meropenem and combined regimens for empirical antibacterial therapy of severe nosocomial infections: results of clinical and pharmacoeconomic analysis].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective A | 2006 |
["Single shot" prevention in abdominal surgery. Antibiotics with long half-life (ceftriaxone, ornidazole) vs. antibiotics with short half-life (cefazolin, metronidazole, clindamycin)].
Topics: Adult; Aged; Anti-Bacterial Agents; Cefazolin; Ceftriaxone; Clindamycin; Cross Infection; Double-Bli | 1994 |
Treatment of asymptomatic Clostridium difficile carriers (fecal excretors) with vancomycin or metronidazole. A randomized, placebo-controlled trial.
Topics: Aged; Bacterial Typing Techniques; Carrier State; Clostridioides difficile; Clostridium Infections; | 1992 |
Selective decontamination to reduce gram-negative colonisation and infections after oesophageal resection.
Topics: Adult; Aged; Cefotaxime; Chi-Square Distribution; Cross Infection; Drug Administration Schedule; Dru | 1990 |
89 other studies available for metronidazole and Cross Infection
| Article | Year |
|---|---|
Clostridium difficile infections in a Canadian tertiary care hospital before and during a regional epidemic associated with the BI/NAP1/027 strain.
Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Community-Acqu | 2008 |
Increasing trends in antimicrobial resistance among clinically important anaerobes and Bacteroides fragilis isolates causing nosocomial infections: emerging resistance to carbapenems.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; Blood; Car | 2008 |
In vitro activity of OPT-80 tested against clinical isolates of toxin-producing Clostridium difficile.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Clostridioides difficile; Cross Infection; Enterocolitis, P | 2008 |
Metronidazole resistance in Prevotella spp. and description of a new nim gene in Prevotella baroniae.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Blotting, Southern; Cross Infection; DNA, Bacteria | 2010 |
Risk factors for recurrent healthcare-facility associated Clostridioides difficile infection in a Swedish setting.
Topics: Anti-Bacterial Agents; Case-Control Studies; Cefotaxime; Clostridioides difficile; Clostridium Infec | 2023 |
Characteristics of Clostridium difficile isolates and the burden of hospital-acquired Clostridium difficile infection in a tertiary teaching hospital in Chongqing, Southwest China.
Topics: Adult; Aged; Anti-Bacterial Agents; Case-Control Studies; China; Clostridioides difficile; Clostridi | 2020 |
Repurposing a platelet aggregation inhibitor ticagrelor as an antimicrobial against Clostridioides difficile.
Topics: Anti-Bacterial Agents; Biofilms; Cell Membrane; Clostridioides difficile; Clostridium Infections; Cr | 2020 |
A preliminary study of bowel rest strategy in the management of Clostridioides difficile infection.
Topics: Aged; Aged, 80 and over; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea | 2020 |
Molecular epidemiology and antimicrobial susceptibility of Clostridium difficile isolates from two Korean hospitals.
Topics: Anti-Bacterial Agents; Asian People; Clostridioides difficile; Clostridium Infections; Cross Infecti | 2017 |
Post-hospitalization Treatment Regimen and Readmission for C. difficile Colitis in Medicare Beneficiaries.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Co | 2018 |
Treating Clostridium difficile infection in patients presenting with hematological malignancies: Are current guidelines applicable?
Topics: Adult; Clostridioides difficile; Clostridium Infections; Cross Infection; Disease Management; Female | 2017 |
Clinical sources and antimicrobial susceptibility of Prevotella timonensis at the university hospital of Montpellier, France.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroidace | 2018 |
The outcome of patients with severe and severe-complicated Clostridium difficile infection treated with tigecycline combination therapy: a retrospective observational study.
Topics: Administration, Intravenous; Aged; Aged, 80 and over; Anti-Bacterial Agents; Australia; Clostridioid | 2018 |
The 'ins and outs' of faecal microbiota transplant for recurrent Clostridium difficile diarrhoea at Wits Donald Gordon Medical Centre, Johannesburg, South Africa.
Topics: Adult; Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infectio | 2018 |
The evolving epidemiology of
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Canada; Clostridioides difficile; Clostridium Infect | 2018 |
A multicenter-based study on epidemiology, antibiotic susceptibility and risk factors of toxigenic Clostridium difficile in hospitalized patients in southwestern Iran.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Clos | 2018 |
Association Between Antibiotic Use and Hospital-onset Clostridioides difficile Infection in US Acute Care Hospitals, 2006-2012: An Ecologic Analysis.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Clostridioides difficile; Clostridium Infections | 2020 |
Characterization and risk factors for recurrence of Clostridioides (Clostridium) difficile infection in Japan: A nationwide real-world analysis using a large hospital-based administrative dataset.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Clostridioides difficile; Clos | 2019 |
Antimicrobial activity of LFF571 and three treatment agents against Clostridium difficile isolates collected for a pan-European survey in 2008: clinical and therapeutic implications.
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infe | 2013 |
[Clostridium difficile infections - still a major challenge].
Topics: Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Combined Modality Thera | 2013 |
Hospital-acquired Clostridium difficile infection among patients with type 2 diabetes mellitus in acute medical wards.
Topics: Abdominal Pain; Age Factors; Aged; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clos | 2013 |
Predictors of first recurrence in Clostridium difficile-associated disease. A study of 306 patients hospitalized in a Romanian tertiary referral center.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides diffi | 2013 |
Risk of Clostridium difficile infection in hospitalized patients receiving metronidazole for a non-C difficile infection.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clostridioides difficile; Cl | 2014 |
Chemoprophylaxis of Clostridium difficile infections in high-risk hospitalized patients.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Clostridioides difficile; Clostridium Infections; Cro | 2014 |
[Epidemiology of Clostridium difficile-associated disease (CDAD) in Salamanca].
Topics: Aged; Aged, 80 and over; Antacids; Anti-Bacterial Agents; Antineoplastic Agents; Clostridioides diff | 2014 |
Healthcare resource utilization for recurrent Clostridium difficile infection in a large university hospital in Houston, Texas.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cr | 2014 |
[Clostridium difficile in visceral surgery].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Clostridioides d | 2015 |
Risk of Clostridium difficile infection in intensive care unit patients with sepsis exposed to metronidazole.
Topics: Aged; Anti-Infective Agents; Case-Control Studies; Clostridioides difficile; Clostridium Infections; | 2015 |
Treatment of Clostridium difficile infection in a French university hospital.
Topics: Adult; Aged; Clostridioides difficile; Cohort Studies; Cross Infection; Drug Therapy, Combination; E | 2015 |
Risk Factors and Outcomes for Bloodstream Infections Secondary to Clostridium difficile Infection.
Topics: Aged; Anti-Infective Agents; Bacteremia; Candida; Candidiasis; Case-Control Studies; Clostridioides | 2016 |
Prospective observational study to compare oral topical metronidazole versus 0.2% chlorhexidine gluconate to prevent nosocomial pneumonia.
Topics: Acinetobacter baumannii; Adult; Aged; Aged, 80 and over; Chlorhexidine; Cross Infection; Female; Hum | 2016 |
Correlation between fecal calprotectin levels, disease severity and the hypervirulent ribotype 027 strain in patients with Clostridium difficile infection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Clostridioides difficile; Clostridium Infect | 2016 |
Molecular types and antimicrobial susceptibility patterns of Clostridium difficile isolates in different epidemiological settings in a tertiary care center in Israel.
Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Clostridioides difficile; Clostridium Infections | 2016 |
Real-Time Electronic Tracking of Diarrheal Episodes and Laxative Therapy Enables Verification of Clostridium difficile Clinical Testing Criteria and Reduction of Clostridium difficile Infection Rates.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Electronic Data Pr | 2017 |
Clindamycin and metronidazole as independent risk factors for nosocomial acquisition of multidrug-resistant Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Clindamycin; Cross Infection; Drug Resistance, Multiple, Bacterial; Humans; M | 2008 |
The timing of surgical antimicrobial prophylaxis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Cefuroxime; Chi-Square Distribut | 2008 |
Characterization of Clostridium difficile strains isolated from immunosuppressed inpatients in a hospital in Rio de Janeiro, Brazil.
Topics: Adult; Anti-Bacterial Agents; Bacterial Toxins; Bacterial Typing Techniques; Brazil; Clostridioides | 2009 |
[Clinical characteristics and changing epidemiology of Clostridium difficile-associated disease (CDAD)].
Topics: Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Bacterial Toxins; Cephalospo | 2009 |
Impact of surgical site infections on length of stay and costs in selected colorectal procedures.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Cefotetan; Colorectal Surgery | 2009 |
Use of International Classification of Diseases, Ninth Revision, Clinical Modification codes and medication use data to identify nosocomial Clostridium difficile infection.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Cross-Sect | 2009 |
Continuing diarrhoea after ten days of oral metronidazole or oral vancomycin for presumed, hospital-acquired Clostridium difficile colitis in elderly hospital patients.
Topics: Aged, 80 and over; Albumins; Anti-Bacterial Agents; C-Reactive Protein; Clostridioides difficile; Cl | 2010 |
Clostridium difficile infection at a medical center in southern Taiwan: incidence, clinical features and prognosis.
Topics: Academic Medical Centers; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteri | 2010 |
Increase in use of vancomycin for Clostridium difficile infection in US hospitals.
Topics: Academic Medical Centers; Adult; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; E | 2010 |
[Clostridium difficile infections at Landspítali - 1998-2008].
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Feces; Hos | 2010 |
Cumulative antibiotic exposures over time and the risk of Clostridium difficile infection.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; En | 2011 |
QT interval prolongation due to metronidazole administration.
Topics: Aged; Anti-Infective Agents; Cross Infection; Drug Therapy, Combination; Electrocardiography; Female | 2011 |
Biodegradable tocopherol acetate as a drug carrier to prevent ureteral stent-associated infection.
Topics: Absorbable Implants; Anti-Infective Agents, Urinary; Bacterial Adhesion; Cross Infection; Drug Carri | 2011 |
Recognizing metronidazole resistant C. difficile.
Topics: Anti-Infective Agents; Clostridioides difficile; Cross Infection; Drug Resistance, Bacterial; Drug T | 2011 |
Susceptibility profiles and resistance genes for carbapenems (cfiA) and metronidazole (nim) among Bacteroides species in a Turkish University Hospital.
Topics: Anti-Bacterial Agents; Bacteroides; Bacteroides Infections; beta-Lactamases; Carbapenems; Cross Infe | 2012 |
Preventing downstream Clostridium difficile infections with upstream antibiotic management.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; | 2012 |
Changing incidence and clinical manifestations of Clostridium difficile-associated diarrhea detected by combination of glutamate dehydrogenase and toxin assay in Northern Taiwan.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Toxins; beta-Lactamases; Clostridio | 2012 |
[Clostridium difficile. Increasing spread outside the hospital].
Topics: Ambulatory Care; Anti-Infective Agents; Clostridioides difficile; Cross Infection; Diagnosis, Differ | 2012 |
A 5-year retrospective review of experience with Clostridium difficile-associated diarrhea.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enterocolitis, Pseudomem | 2012 |
Incidence and clinical features of Clostridium difficile infection in Korea: a nationwide study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Clostridium Infecti | 2013 |
[Clostridium-difficile-colitis: more frequent and more severe].
Topics: Adult; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Clos | 2012 |
Outcome of ICU patients with Clostridium difficile infection.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Community-Acquired In | 2012 |
Resistance of Bacteroides isolates recovered among clinical samples from a major Costa Rican hospital between 2000 and 2008 to ß-lactams, clindamycin, metronidazole, and chloramphenicol.
Topics: Anti-Bacterial Agents; Bacteroides; Bacteroides Infections; beta-Lactam Resistance; beta-Lactams; Ch | 2012 |
UROGENITAL TRICHOMONIASIS; TREATMENT WITH METRONIDAZOLE IN 2002 INCARCERATED WOMEN.
Topics: Coitus; Cross Infection; Epidemiology; Female; Humans; Metronidazole; Prognosis; Statistics as Topic | 1964 |
In-vitro activity of nisin against clinical isolates of Clostridium difficile.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; H | 2004 |
Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Chi-Square Distribution; Child; Clostridioides diffi | 2004 |
Surveillance for resistance to metronidazole and vancomycin in genotypically distinct and UK epidemic Clostridium difficile isolates in a large teaching hospital.
Topics: Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Drug Resistance, Bacterial; Entero | 2005 |
Management of an outbreak of Clostridium difficile-associated disease among geriatric patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Clostridioides difficile; Cross Infection; Disease O | 2006 |
Prevalence of extended-spectrum beta-lactamase-producing enterobacteriaceae in Maltese hospitalized patients.
Topics: beta-Lactam Resistance; beta-Lactamases; Cross Infection; Cross-Sectional Studies; Enterobacteriacea | 2007 |
[Clostridium difficile associated diarrhea in the elderly patient].
Topics: Age Factors; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Clostridioides difficile; Cross Inf | 2007 |
Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcome.
Topics: Adult; Anti-Infective Agents; Child; Clostridioides difficile; Cohort Studies; Cross Infection; Ente | 2007 |
Large variation in antibacterial use among Norwegian nursing homes.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cross Infection; Cross-Sectional Studies; Drug Resistan | 2007 |
A case of recurrent Clostridium difficile diarrhea.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Clostridioides difficile; Cross Infection; Diarrhea; Enter | 2007 |
A study of Clostridium difficile-associated disease at King Chulalongkorn Memorial Hospital, Thailand.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbapenems; Cephalosporins; Child; Child, Preschool; Cl | 2008 |
Diagnostic and treatment delays in recurrent Clostridium difficile-associated disease.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Clostridium Infections; Cohort Studies; Cross | 2008 |
Both oral metronidazole and oral vancomycin promote persistent overgrowth of vancomycin-resistant enterococci during treatment of Clostridium difficile-associated disease.
Topics: Administration, Oral; Aged; Aged, 80 and over; Clostridioides difficile; Cross Infection; Enterococc | 2008 |
Ten years of prospective Clostridium difficile-associated disease surveillance and treatment at the Minneapolis VA Medical Center, 1982-1991.
Topics: Administration, Oral; Clostridioides difficile; Cross Infection; Enterocolitis, Pseudomembranous; Fe | 1994 |
[Combatting nosocomial intestinal infections with yeasts].
Topics: Combined Modality Therapy; Cross Infection; Enterocolitis, Pseudomembranous; Humans; Metronidazole; | 1995 |
Clostridium difficile colitis: an increasing hospital-acquired illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Child; Child, Pre | 1995 |
Management and control of a large outbreak of diarrhoea due to Clostridium difficile.
Topics: Aged; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostridium Infections; Cross | 1994 |
Stopping an epidemic of Clostridium difficile diarrhea.
Topics: Clindamycin; Cross Infection; Diarrhea; Enterocolitis, Pseudomembranous; Humans; Metronidazole | 1994 |
[Survey with three epidemiological markers after 22 cases of diarrhea caused by Clostridium difficile in a geriatric hospital].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Bacterial Proteins; Bacterial | 1993 |
Studies on drug monitoring in thrice and once daily treatment with aminoglycosides.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefotaxime; Cross Infection; Dose-Response Relationship, | 1993 |
Risk factors for mortality associated with enterococcal bloodstream infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Cohor | 1996 |
Audit on the use of prophylactic parenteral antimicrobial agents and the use of co-amoxiclav and metronidazole.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antitrichomonal A | 1996 |
Diarrhoea in the intensive care unit.
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Cross Infection; Diarrhea; Humans; Intensive Care Uni | 1997 |
[Perioperative antibiotic prophylaxis in visceral surgery--pro and contra].
Topics: Antibiotic Prophylaxis; Cephalosporins; Cross Infection; Drug Therapy, Combination; Gastrointestinal | 1997 |
Vancomycin-resistant and vancomycin-susceptible enterococcal bacteremia: comparison of clinical features and outcomes.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Case-Control Studies; Cross Infection; Drug Resistan | 1998 |
Clostridium difficile-associated diarrhea in the elderly.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anti-Bacterial Agents; Child; Clostridioides diff | 1999 |
Evolution of metronidazole and tetracycline susceptibility pattern in Helicobacter pylori at a hospital in Saudi Arabia.
Topics: Anti-Bacterial Agents; Cross Infection; Drug Resistance, Microbial; Female; Helicobacter Infections; | 2001 |
Clostridium difficile infection in patients with neutropenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antineoplastic Agents; Cross Infe | 2001 |
[Prevalence of primary Helicobacter pylori resistance to eight antimicrobial agents in a hospital in Madrid].
Topics: Adult; Aged; Amoxicillin; Azithromycin; Cefotaxime; Ciprofloxacin; Clarithromycin; Clindamycin; Cros | 2001 |
E test susceptibility testing of nosocomial Clostridium difficile isolates against metronidazole, vancomycin, fusidic acid and the novel agents moxifloxacin, gatifloxacin, and linezolid.
Topics: Acetamides; Anti-Infective Agents; Aza Compounds; Clostridioides difficile; Clostridium Infections; | 2002 |
Clostridium difficile in the intensive care unit: management problems and prevention issues.
Topics: Aged; Cross Infection; Enterocolitis, Pseudomembranous; Feces; Female; Humans; Intensive Care Units; | 1989 |
Timentin in the treatment of nosocomial bronchopulmonary infections in intensive care units.
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bronchitis; Cla | 1986 |