metronidazole has been researched along with Cranial Sinus Thrombosis in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ching, HY | 1 |
| Ramsden, JD | 1 |
| Bottrill, I | 1 |
| Repanos, C | 1 |
| Chadha, NK | 1 |
| Griffiths, MV | 1 |
| Commins, DJ | 1 |
| Koay, B | 1 |
| Milford, CA | 1 |
| Renowden, S | 1 |
| Jones, TH | 1 |
| Bergvall, V | 1 |
| Bradshaw, JP | 1 |
4 other studies available for metronidazole and Cranial Sinus Thrombosis
| Article | Year |
|---|---|
A unique presentation: Bezold's abscess and glomerulonephritis.
Topics: Abscess; Adolescent; Anti-Infective Agents; Ceftriaxone; Drainage; Glomerulonephritis; Humans; Male; | 2006 |
Sigmoid sinus thrombosis secondary to Lemierre's syndrome.
Topics: Adult; Anticoagulants; Cefuroxime; Drainage; Humans; Jugular Veins; Magnetic Resonance Imaging; Male | 2006 |
Otitic hydrocephalus.
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Cefotaxime; Cephalosporins; Child; Humans; Hydrocepha | 1997 |
Carotid artery stenoses and thrombosis secondary to cavernous sinus thromboses in Fusobacterium necrophorum meningitis.
Topics: Adult; Arterial Occlusive Diseases; Carotid Artery Diseases; Carotid Artery Thrombosis; Cavernous Si | 1990 |