metronidazole has been researched along with Corynebacterium Infections in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Corynebacterium Infections: Infections with bacteria of the genus CORYNEBACTERIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A tension pneumopericardium has to be treated with immediate pericardiocentesis followed by partial pericardiectomy to avoid recurrence." | 1.32 | Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia. ( Bleeker-Rovers, CP; Bloemen, TI; Kaasjager, HA; van den Elshout, FJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brownson, KE | 1 |
| Bertoni, DM | 1 |
| Lannin, DR | 1 |
| Cohen, PJ | 1 |
| Pronovost, MT | 1 |
| Bleeker-Rovers, CP | 1 |
| van den Elshout, FJ | 1 |
| Bloemen, TI | 1 |
| Kaasjager, HA | 1 |
| Balsdon, MJ | 1 |
| Maskell, R | 2 |
| Goei, SH | 1 |
| Wells, JI | 1 |
| McCormack, WM | 1 |
| Josey, WE | 1 |
| Banner, EA | 1 |
| Heiss, H | 1 |
1 review available for metronidazole and Corynebacterium Infections
| Article | Year |
|---|---|
Management of sexually transmissible infections during pregnancy.
Topics: Anti-Bacterial Agents; Candidiasis; Chlamydia Infections; Coitus; Condylomata Acuminata; Corynebacte | 1975 |
1 trial available for metronidazole and Corynebacterium Infections
| Article | Year |
|---|---|
[Clinical evaluation of medicines active against trichomoniasis vaginalis in a double-blind study].
Topics: Adolescent; Adult; Age Factors; Antiprotozoal Agents; Candidiasis, Vulvovaginal; Child; Clinical Tri | 1971 |
7 other studies available for metronidazole and Corynebacterium Infections
| Article | Year |
|---|---|
Granulomatous lobular mastitis-Another paradigm shift in treatment.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Biopsy, Large-Core Needle; Clavulanic Acid; Corynebacteri | 2019 |
Tension pneumopericardium caused by positive pressure ventilation complicating anaerobic pneumonia.
Topics: Adult; Bacteroides fragilis; Bacteroides Infections; Cardiac Tamponade; Clindamycin; Corynebacterium | 2003 |
Metronidazole for Corynebacterium vaginale vaginitis.
Topics: Corynebacterium Infections; Female; Humans; Metronidazole; Vaginitis | 1980 |
Gardnerella vaginalis and prostatitis.
Topics: Corynebacterium; Corynebacterium Infections; Humans; Male; Metronidazole; Prostatitis | 1981 |
Corynebacterium vaginale in non-purulent vaginitis.
Topics: Adolescent; Adult; Corynebacterium; Corynebacterium Infections; Female; Humans; Metronidazole; Middl | 1981 |
Vaginitis. Reducing the number of refractory cases.
Topics: Ampicillin; Candidiasis, Vulvovaginal; Contraception; Corynebacterium Infections; Female; Humans; Me | 1977 |
Vaginitis.
Topics: Adolescent; Candida albicans; Candidiasis, Vulvovaginal; Child; Corynebacterium Infections; Female; | 1974 |