metronidazole has been researched along with Complications, Infectious Pregnancy in 168 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This was a sub-study of a larger randomized trial of oral versus vaginal metronidazole for treatment of BV in pregnancy." | 9.14 | Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria. ( Agnew, KJ; Fredricks, DN; Hitti, JE; Mitchell, CM, 2009) |
| "This was a randomized controlled trial comparing oral and intravaginal metronidazole for treatment of BV in early pregnancy (<20 weeks)." | 9.14 | Changes in the vaginal microenvironment with metronidazole treatment for bacterial vaginosis in early pregnancy. ( Agnew, K; Balkus, J; Hitti, J; Lawler, R; Mitchell, C, 2009) |
| "One week of oral metronidazole and 5 days of intravaginal metronidazole are equally efficacious for treatment of bacterial vaginosis during pregnancy." | 9.10 | Clinical and cervical cytokine response to treatment with oral or vaginal metronidazole for bacterial vaginosis during pregnancy: a randomized trial. ( Hillier, SL; Landers, DV; Meyn, L; Yudin, MH, 2003) |
| "To characterize the natural history of bacterial vaginosis in pregnancy and to assess the efficacy of short courses of oral metronidazole therapy for long-term suppression of bacterial vaginosis flora." | 9.07 | Bacterial vaginosis in pregnancy and efficacy of short-course oral metronidazole treatment: a randomized controlled trial. ( Jolley, PT; McDonald, HM; McDonald, PJ; O'Loughlin, JA; Vigneswaran, R, 1994) |
| "Our purpose was to determine whether treatment of bacterial vaginosis with metronidazole in patients with preterm delivery in the penultimate pregnancy from preterm labor or premature rupture of membranes reduces the risk of subsequent preterm birth." | 9.07 | Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: a placebo-controlled, double-blind study. ( Albritton, J; Morales, WJ; Schorr, S, 1994) |
| " A recent clinical recommendation by a guidelines group of the Danish Society of Obstetrics and Gynecology advised against the use of clindamycin for the treatment of bacterial vaginosis in pregnancy to reduce the risk of spontaneous preterm birth based on lack of evidence of efficacy." | 7.85 | The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations. ( Jørgensen, JS; Keelan, JA; Lamont, RF; Larsson, PG, 2017) |
| "Four patients with Bacteroides fragilis bacteremia, one patient with a brain abscess due to Bacteroides species, Fusobacterium naviforme, and Peptostreptococcus species, and an infant with Bacteroides species ventriculitis and meningitis were treated with metronidazole." | 7.66 | Metronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess. ( Cordero, L; Perkins, RL; Warner, JF, 1979) |
| "Metronidazole was found to be effective in preventing preterm births when used in conjunction with other antibiotics." | 5.62 | The safety of metronidazole in pregnancy. ( Bloom, K; Nwosu, OC, 2021) |
| "Although absolute estimates of metronidazole total body exposure were highest in women during early term pregnancy, weight-corrected estimates of exposure maximum plasma drug concentration (C(max)) and the area under the plasma concentration-versus-time curve (AUC(0-12)), along with apparent oral clearance and distribution volume, were not significantly different between women at early, middle, and late stages of pregnancy and were in the range of reported values for nonpregnant patients receiving a similar dose." | 5.15 | Pharmacokinetics of metronidazole in pregnant patients with bacterial vaginosis. ( Abdel-Rahman, SM; Ahmed, MS; Hankins, GD; Jasek, M; Nanovskaya, TN; Wang, X; Zhan, Y, 2011) |
| "A randomized, double-blind, placebo-controlled trial with 280 women between 16 and 18 weeks of pregnancy who had 1 previous preterm birth and had just been successfully treated for bacterial vaginosis with metronidazole for 1 week." | 5.14 | Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis. ( Hassanin, IM; Hirchenhain, J; Ismail, AM; Kruessel, JS; Shahin, AY, 2009) |
| "This was a sub-study of a larger randomized trial of oral versus vaginal metronidazole for treatment of BV in pregnancy." | 5.14 | Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria. ( Agnew, KJ; Fredricks, DN; Hitti, JE; Mitchell, CM, 2009) |
| "This was a randomized controlled trial comparing oral and intravaginal metronidazole for treatment of BV in early pregnancy (<20 weeks)." | 5.14 | Changes in the vaginal microenvironment with metronidazole treatment for bacterial vaginosis in early pregnancy. ( Agnew, K; Balkus, J; Hitti, J; Lawler, R; Mitchell, C, 2009) |
| "To determine whether metronidazole reduces early preterm labour in asymptomatic women with positive vaginal fetal fibronectin (fFN) in the second trimester of pregnancy." | 5.12 | A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study. ( Briley, A; Crawshaw, S; Hawken, J; Jones, G; Poston, L; Seed, P; Shennan, A, 2006) |
| "One week of oral metronidazole and 5 days of intravaginal metronidazole are equally efficacious for treatment of bacterial vaginosis during pregnancy." | 5.10 | Clinical and cervical cytokine response to treatment with oral or vaginal metronidazole for bacterial vaginosis during pregnancy: a randomized trial. ( Hillier, SL; Landers, DV; Meyn, L; Yudin, MH, 2003) |
| " Adjunctive metronidazole therapy did not improve pregnancy outcome." | 5.10 | Periodontal disease and preterm birth: results of a pilot intervention study. ( Cliver, SP; Geurs, NC; Goldenberg, RL; Hauth, JC; Hodgkins, PM; Jeffcoat, MK; Reddy, MS, 2003) |
| "Treatment of Trichomonas vaginalis during pregnancy may be deleterious, and we infer that this may be due to metronidazole." | 5.10 | Treatment of Trichomonas in pregnancy and adverse outcomes of pregnancy: a subanalysis of a randomized trial in Rakai, Uganda. ( Brahmbhatt, H; Gray, RH; Kigozi, GG; Serwadda, D; Sewankambo, N; Wabwire-Mangen, F; Wawer, MJ, 2003) |
| "Our purpose was to determine whether treatment of bacterial vaginosis with metronidazole in patients with preterm delivery in the penultimate pregnancy from preterm labor or premature rupture of membranes reduces the risk of subsequent preterm birth." | 5.07 | Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: a placebo-controlled, double-blind study. ( Albritton, J; Morales, WJ; Schorr, S, 1994) |
| "To characterize the natural history of bacterial vaginosis in pregnancy and to assess the efficacy of short courses of oral metronidazole therapy for long-term suppression of bacterial vaginosis flora." | 5.07 | Bacterial vaginosis in pregnancy and efficacy of short-course oral metronidazole treatment: a randomized controlled trial. ( Jolley, PT; McDonald, HM; McDonald, PJ; O'Loughlin, JA; Vigneswaran, R, 1994) |
| "To evaluate whether treatment of BV with vaginal clindamycin or oral metronidazole before 28 weeks of pregnancy reduces PTL incidence." | 5.01 | Treatment of bacterial vaginosis before 28 weeks of pregnancy to reduce the incidence of preterm labor. ( Cobucci, RN; Costa, APF; Eleutério, J; Gonçalves, AK; Peixoto, RC; Rebouças, KF, 2019) |
| " Thus, the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (NICHD MFMU) Network performed a randomized clinical trial to determine if antibiotic treatment (metronidazole plus erythromycin) of asymptomatic women with a positive cervical or vaginal fetal fibronectin test in early pregnancy will reduce the risk of spontaneous preterm delivery." | 4.82 | What we have learned from an antibiotic trial in fetal fibronectin positive women. ( Andrews, WW; Goldenberg, RL, 2003) |
| "In order to assess whether the use of metronidazole during pregnancy is associated with a higher risk of congenital malformations, a meta-analysis was conducted." | 4.79 | Is metronidazole teratogenic? A meta-analysis. ( Alvarez Requejo, A; Caro-Patón, T; Carvajal, A; Martin de Diego, I; Martin-Arias, LH; Rodríguez Pinilla, E, 1997) |
| "After adjustment for potential confounders, use of macro-lides (excluding erythromycin), quinolones, tetracyclines, sulfonamides and metronidazole during early pregnancy was associated with an increased risk of spontaneous abortion." | 3.85 | Use of antibiotics during pregnancy and risk of spontaneous abortion. ( Bérard, A; Muanda, FT; Sheehy, O, 2017) |
| " A recent clinical recommendation by a guidelines group of the Danish Society of Obstetrics and Gynecology advised against the use of clindamycin for the treatment of bacterial vaginosis in pregnancy to reduce the risk of spontaneous preterm birth based on lack of evidence of efficacy." | 3.85 | The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations. ( Jørgensen, JS; Keelan, JA; Lamont, RF; Larsson, PG, 2017) |
| "A new antibiotic combination consisting of ceftriaxone, clarithromycin, and metronidazole prolonged the latency period, reduced acute histologic chorioamnionitis/funisitis, and improved neonatal outcomes in patients with preterm PROM." | 3.83 | A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM. ( Chaemsaithong, P; Jun, JK; Kim, SM; Lee, J; Park, CW; Park, JS; Romero, R; Yoon, BH, 2016) |
| " For this reason, the present study was conducted to investigate the effectiveness of octenidine dihydrochloride/phenoxyethanol (OHP) in comparison to antimicrobial therapies in pregnant women in hospital suffering from different types of vaginitis." | 3.81 | Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women. ( Novakov Mikić, A; Stojic, S, 2015) |
| "The purpose of this study was to determine if a change in the vaginal flora was associated with an increased risk of preterm birth, and to determine if metronidazole therapy before 32 weeks increased the risk of preterm birth." | 3.73 | Is a change in the vaginal flora associated with an increased risk of preterm birth? ( Carey, JC; Klebanoff, MA, 2005) |
| " Only 12% of physicians prescribed oral metronidazole or clindamycin during the first trimester of pregnancy to treat BV." | 3.72 | Bacterial vaginosis in pregnancy: diagnosis and treatment practices of physicians in San Diego, California, 1999. ( Callahan, DB; Gunn, RA; Weinberg, M, 2003) |
| " This study was carried out to find out the prevalence of Bacterial Vaginosis (BV) in antenatal women with vaginal discharge and the effect of treatment with Metronidazole gel on pregnancy outcome." | 3.71 | Prevalence of bacterial vaginosis in antenatal women. ( Bibi, R; Kalyani, J; Mallika, M; Mathew, R, 2001) |
| "We evaluated the timing of initial antenatal visits to better characterize possible use of metronidazole or other antimicrobials for common reproductive tract infections in early pregnancy." | 3.69 | First antenatal visits and metronidazole. ( McGregor, JA; Roberts, AM, 1997) |
| "A single 2-g dose of benzoylmetronidazole (Flagyl suspension) was given to patients with vaginal trichomoniasis in the second and third trimesters of pregnancy." | 3.66 | Trichomoniasis treated with a single dose of benzoylmetronidazole. ( Roos, RF, 1978) |
| "Four patients with Bacteroides fragilis bacteremia, one patient with a brain abscess due to Bacteroides species, Fusobacterium naviforme, and Peptostreptococcus species, and an infant with Bacteroides species ventriculitis and meningitis were treated with metronidazole." | 3.66 | Metronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess. ( Cordero, L; Perkins, RL; Warner, JF, 1979) |
| "The relationship between bacterial vaginosis (BV) and preterm delivery has become well known in recent years, although there are few studies on: (i) the differences in test results during the early gestational (EGP) and middle gestational (MGP) periods; (ii) the significance of the intermediate (I) group that does not develop overt BV; or (iii) the therapeutic effects of metronidazole." | 2.90 | Association between preterm delivery and bacterial vaginosis with or without treatment. ( Doh, K; Kotani, Y; Mandai, M; Matsumura, N; Shimaoka, M; Suzuki, A; Tsuji, I; Yo, Y, 2019) |
| " No serious adverse events were reported, and incidence was similar across treatment groups." | 2.80 | A Phase 3, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of Metronidazole Vaginal Gel 1.3% in the Treatment of Bacterial Vaginosis. ( Beelen, AP; Marrazzo, J; Schwebke, JR; Sobel, JD, 2015) |
| "Women with asymptomatic bacterial vaginosis on Gram stain were assigned randomly at 16 to 23 weeks of gestation to receive two 2-g doses of metronidazole or placebo 48 hours apart and were re-evaluated for changes in Gram stain score on one occasion > or =2 weeks later." | 2.71 | Time course of the regression of asymptomatic bacterial vaginosis in pregnancy with and without treatment. ( Carey, JC; Dombrowski, MP; Hauth, JC; Heine, RP; Iams, JD; Klebanoff, MA; MacPherson, CA; Miodovnik, M; Moawad, A; Sibai, BM; vanDorsten, JP; Wapner, RJ, 2004) |
| "Sexually transmitted diseases were reduced: Trichomonas vaginalis (rate ratio, 0." | 2.70 | Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda. ( Abramowsky, C; Gray, RH; Kigozi, G; Meehan, M; Moulton, LH; O'Brien, KL; Quinn, TC; Robb, M; Serwadda, D; Sewankambo, NK; Wabwire-Mangen, F; Wawer, MJ, 2001) |
| "Bacterial vaginosis was eradicated in 93% of women using intravaginal clindamycin and in 87% of women using intravaginal metronidazole." | 2.69 | [Therapeutic regimens for treating bacterial vaginosis in pregnant women]. ( Borisov, I; Dimitrova, V; Mazneĭkova, V; Shopova, E, 1999) |
| "Treatment with metronidazole did not reduce the occurrence of preterm labor, intraamniotic or postpartum infections, neonatal sepsis, or admission of the infant to the neonatal intensive care unit." | 2.69 | Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. ( Carey, JC; Ernest, JM; Fischer, ML; Hauth, JC; Heine, RP; Hillier, SL; Klebanoff, MA; Leveno, KJ; Nugent, RP; Thom, EA; Varner, M; Wapner, R, 2000) |
| "Treatment with metronidazole and erythromycin reduced rates of premature delivery in women with bacterial vaginosis and an increased risk for preterm delivery." | 2.68 | Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis. ( Andrews, WW; Copper, RL; DuBard, MB; Goldenberg, RL; Hauth, JC, 1995) |
| "Accuracy of screening tests for bacterial vaginosis varies." | 2.66 | Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to Prevent Preterm Delivery: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. ( Berkman, N; Clark, R; Kahwati, LC; Patel, SV; Urrutia, R; Viswanathan, M; Zeng, J, 2020) |
| "Preterm birth is the major cause of perinatal mortality and morbidity in high-income countries." | 2.50 | The early use of appropriate prophylactic antibiotics in susceptible women for the prevention of preterm birth of infectious etiology. ( Joergensen, JS; Kjær Weile, LK; Lamont, RF, 2014) |
| "Candida vulvovaginitis is a fungal infection that is very amenable to topical treatment." | 2.47 | Antimicrobial topical agents used in the vagina. ( Frey Tirri, B, 2011) |
| "Bacterial vaginosis is associated with infectious complications in pregnant and non-pregnant women and increasing risk of STI." | 2.44 | [The bacterial vaginosis--treatment problems]. ( Ekiel, AM; Martirosian, G; Romanik, MK; Tomana, L, 2007) |
| "Whether bacterial vaginosis (BV) is acquired from an endogenous or an exogenous source is subject to controversy." | 2.43 | Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma. ( Bergström, M; Forsum, U; Jacobsson, B; Larsson, PG; Strand, A; Wölner-Hanssen, P, 2005) |
| "Metronidazole treatment of women with trichomoniasis significantly increased the risk of preterm birth compared to placebo." | 2.42 | What have we learned about vaginal infections and preterm birth? ( Carey, JC; Klebanoff, MA, 2003) |
| " The standard treatment is oral metronidazole in a dosage of 500 mg twice daily for seven days." | 2.42 | Management of vaginitis. ( Clenney, TL; Owen, MK, 2004) |
| "Treatment of asymptomatic bacterial vaginosis or T." | 2.41 | Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy. ( Carey, JC; Klebanoff, MA, 2001) |
| "Bacterial vaginosis is also associated with preterm delivery in certain risk groups, such as women with a history of preterm birth or of low maternal weight." | 2.41 | Treatment of sexually transmitted bacterial diseases in pregnant women. ( Donders, GG, 2000) |
| "Prevention and treatment of sexually transmitted infections (STIs) in the sexually active population are the main steps to prevent perinatal infection." | 2.41 | Sexually transmitted infections, adverse pregnancy outcome and neonatal infection. ( Moodley, P; Sturm, AW, 2000) |
| "Bacterial vaginosis is associated with adverse pregnancy outcomes across all gestational ages." | 2.41 | Bacterial vaginosis in pregnancy. ( Ugwumadu, AH, 2002) |
| "Bacterial vaginosis is the most common cause of vaginal discharge." | 2.40 | Bacterial vaginosis: an update. ( Majeroni, BA, 1998) |
| "Here we discuss bacterial vaginosis, which often goes unrecognised despite being the cause of 40-50% of vaginal infections." | 2.40 | Management of bacterial vaginosis. ( , 1998) |
| "Metronidazole is a cost-effective agent due to its low acquisition cost, its pharmacokinetics and pharmacodynamics, an acceptable adverse effect profile, and its undiminished antimicrobial activity." | 2.40 | Metronidazole. A therapeutic review and update. ( Freeman, CD; Klutman, NE; Lamp, KC, 1997) |
| "The importance for screening for bacterial vaginosis is pointed out especially before intrauterine procedures and in pregnant women at risk for premature deliveries." | 2.40 | [Current treatment of bacterial vaginosis]. ( Borisov, I, 1999) |
| "Studies addressing the complications of bacterial vaginosis in pregnancy, the risk of treatment in pregnancy, and the method of transmission of the disease also were reviewed." | 2.39 | Treatment of bacterial vaginosis. ( Schlicht, JR, 1994) |
| "We reviewed data on the treatment of bacterial vaginosis published from 1989 through 1992 (articles published after the 1989 publication of the Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines)." | 2.39 | Bacterial vaginosis: review of treatment options and potential clinical indications for therapy. ( Joesoef, MR; Schmid, GP, 1995) |
| "Other causes of vaginitis are also discussed." | 2.37 | Vaginitis: current microbiologic and clinical concepts. ( Embil, JA; Hill, LV, 1986) |
| "Metronidazole was found to be effective in preventing preterm births when used in conjunction with other antibiotics." | 1.62 | The safety of metronidazole in pregnancy. ( Bloom, K; Nwosu, OC, 2021) |
| "Infection of a maternal urachal cyst during pregnancy is rare; Sonography is an important diagnostic tool that can help minimize maternal and fetal complications." | 1.48 | Sonographic detection of an infected maternal urachal cyst during pregnancy. ( Sargent, J; Sohaey, R; Trivedi, N, 2018) |
| "Vulvovaginal candidiasis affects 75% of women at least once." | 1.42 | Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis. ( van Schalkwyk, J; Yudin, MH, 2015) |
| "Brain abscess is a rare but life-threatening complication of pregnancy." | 1.37 | Pregnancy complicated by recurrent brain abscess after extraction of an infected tooth. ( Awonuga, AO; Hobson, DTG; Imudia, AN; Soto, E, 2011) |
| "In women with bacterial vaginosis, intermediate flora and normal flora, the conception rates were 35% (9/26), 42% (14/33) and 58% (7/12), respectively (p = 0." | 1.37 | Effective of metronidazole to bacterial flora in vagina and the impact of microbes on live birth rate during intracytoplasmic sperm injection (ICSI). ( Alasbahi, AA; Aziz, MH; El Alfy, SM; Mohamed, HM; Selim, SA, 2011) |
| "Treatment by metronidazole or clindamycin was used." | 1.36 | Bacterial vaginosis in threatened preterm, preterm and term labour. ( Chawanpaiboon, S; Pimol, K, 2010) |
| "As metronidazole effectively treats full BV, but is ineffective against other forms of AVF, the present data may help to explain why its use to prevent PTB has not been successful in most studies." | 1.35 | Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy. ( Bellen, G; Donders, GG; Reybrouck, R; Riphagen, I; Van Calsteren, K; Van den Bosch, T; Van Lierde, S, 2009) |
| "Research on the relationship between sexually transmitted diseases (STDs) and HIV was presented at the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)." | 1.30 | Data on HIV infection in women expands. ( Eagan, L, 1999) |
| "Metronidazole treatment during pregnancy should be resorted to only when absolutely essential." | 1.28 | Trichomoniasis: trends in diagnosis and management. ( Kent, HL; Lossick, JG, 1991) |
| "A reported excess of liver tumors in rats exposed to metronidazole can be explained by the fact that the authors failed to age standardize their data despite a big and highly significant beneficial effect of the drug on survival." | 1.27 | Toxicologic evaluation of metronidazole with particular reference to carcinogenic, mutagenic, and teratogenic potential. ( Roe, FJ, 1983) |
| "One female developed septicemia after cancer surgery, one male after heart surgery." | 1.27 | Septicemia due to Mycoplasma hominis. ( Bøe, O; Iversen, OE; Mehl, A, 1983) |
| "Metronidazole which has been widely used in the treatment of trichomoniasis urogenitalis is the most active agent available against obligate anaerobes." | 1.27 | [Metronidazole in the treatment and prevention of infections in gynecology and obstetrics]. ( Amon, I; Amon, K, 1983) |
| " The mean elimination half-life values were 5." | 1.26 | Pharmacokinetics of Metronidazole in pregnant women. ( Amon, I; Amon, K; Franke, G; Mohr, C, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 58 (34.52) | 18.7374 |
| 1990's | 28 (16.67) | 18.2507 |
| 2000's | 46 (27.38) | 29.6817 |
| 2010's | 31 (18.45) | 24.3611 |
| 2020's | 5 (2.98) | 2.80 |
| Authors | Studies |
|---|---|
| Germano, C | 1 |
| Messina, A | 1 |
| Massaro, A | 1 |
| Attini, R | 1 |
| Leo, L | 1 |
| Manzoni, P | 1 |
| Masturzo, B | 1 |
| Gadoth, A | 1 |
| Shannon, CL | 1 |
| Hoff, NA | 1 |
| Mvumbi, G | 1 |
| Musene, K | 1 |
| Okitolonda-Wemakoy, E | 1 |
| Hoffman, RM | 1 |
| Rimoin, AW | 1 |
| Klausner, JD | 1 |
| Kahwati, LC | 1 |
| Clark, R | 1 |
| Berkman, N | 1 |
| Urrutia, R | 1 |
| Patel, SV | 1 |
| Zeng, J | 1 |
| Viswanathan, M | 1 |
| Vodstrcil, LA | 1 |
| Bradshaw, CS | 1 |
| Nwosu, OC | 1 |
| Bloom, K | 1 |
| Muanda, FT | 1 |
| Sheehy, O | 1 |
| Bérard, A | 1 |
| Sargent, J | 1 |
| Sohaey, R | 1 |
| Trivedi, N | 1 |
| Thi Trung Thu, T | 1 |
| Margarita, V | 1 |
| Cocco, AR | 1 |
| Marongiu, A | 1 |
| Dessì, D | 1 |
| Rappelli, P | 1 |
| Fiori, PL | 1 |
| Dinglas, C | 1 |
| Chavez, M | 1 |
| Vintzileos, A | 1 |
| Shimaoka, M | 1 |
| Yo, Y | 1 |
| Doh, K | 1 |
| Kotani, Y | 1 |
| Suzuki, A | 1 |
| Tsuji, I | 1 |
| Mandai, M | 1 |
| Matsumura, N | 1 |
| Yoon, BH | 2 |
| Romero, R | 2 |
| Park, JY | 1 |
| Oh, KJ | 1 |
| Lee, J | 2 |
| Conde-Agudelo, A | 1 |
| Hong, JS | 1 |
| Rebouças, KF | 1 |
| Eleutério, J | 1 |
| Peixoto, RC | 1 |
| Costa, APF | 1 |
| Cobucci, RN | 1 |
| Gonçalves, AK | 1 |
| Yefet, E | 1 |
| Romano, S | 1 |
| Chazan, B | 1 |
| Nachum, Z | 1 |
| Nashaat, EH | 3 |
| Mansour, GM | 3 |
| Doubova, SV | 1 |
| Pérez-Cuevas, R | 1 |
| Ortiz-Panozo, E | 1 |
| Hernández-Prado, B | 1 |
| Joergensen, JS | 1 |
| Kjær Weile, LK | 1 |
| Lamont, RF | 3 |
| Han, C | 1 |
| Wu, W | 1 |
| Fan, A | 1 |
| Wang, Y | 1 |
| Zhang, H | 1 |
| Chu, Z | 1 |
| Wang, C | 1 |
| Xue, F | 1 |
| Novakov Mikić, A | 1 |
| Stojic, S | 1 |
| van Schalkwyk, J | 1 |
| Yudin, MH | 2 |
| Schwebke, JR | 1 |
| Marrazzo, J | 1 |
| Beelen, AP | 1 |
| Sobel, JD | 1 |
| Kim, SM | 1 |
| Chaemsaithong, P | 1 |
| Park, CW | 1 |
| Park, JS | 1 |
| Jun, JK | 1 |
| Haahr, T | 1 |
| Ersbøll, AS | 1 |
| Karlsen, MA | 1 |
| Svare, J | 1 |
| Sneider, K | 1 |
| Hee, L | 1 |
| Weile, LK | 1 |
| Ziobrowska-Bech, A | 1 |
| Østergaard, C | 1 |
| Jensen, JS | 1 |
| Helmig, RB | 1 |
| Uldbjerg, N | 1 |
| Alcaraz, I | 1 |
| Vermersch-Langlin, A | 1 |
| Mazars, E | 1 |
| Janier, M | 1 |
| Dupin, N | 1 |
| Pelletier, F | 1 |
| Keelan, JA | 1 |
| Larsson, PG | 2 |
| Jørgensen, JS | 1 |
| Mastrobattista, JM | 1 |
| Klebanoff, MA | 8 |
| Carey, JC | 7 |
| Hauth, JC | 6 |
| Macpherson, CA | 2 |
| Ernest, J | 1 |
| Cotroneo, M | 1 |
| Leveno, KJ | 2 |
| Wapner, R | 2 |
| Varner, M | 2 |
| Iams, JD | 2 |
| Moawad, A | 3 |
| Sibai, BM | 2 |
| Miodovnik, M | 3 |
| Dombrowski, M | 2 |
| O'Sullivan, MJ | 2 |
| Vandorsten, JP | 2 |
| Langer, O | 2 |
| Garey, KW | 1 |
| Jiang, ZD | 1 |
| Yadav, Y | 1 |
| Mullins, B | 1 |
| Wong, K | 1 |
| Dupont, HL | 1 |
| Schwebke, J | 1 |
| Shahin, AY | 1 |
| Hassanin, IM | 1 |
| Ismail, AM | 1 |
| Kruessel, JS | 1 |
| Hirchenhain, J | 1 |
| Milánkovits, M | 1 |
| Mitchell, CM | 1 |
| Hitti, JE | 1 |
| Agnew, KJ | 1 |
| Fredricks, DN | 1 |
| Donders, GG | 3 |
| Van Calsteren, K | 1 |
| Bellen, G | 1 |
| Reybrouck, R | 1 |
| Van den Bosch, T | 2 |
| Riphagen, I | 2 |
| Van Lierde, S | 1 |
| Mitchell, C | 1 |
| Balkus, J | 1 |
| Agnew, K | 1 |
| Lawler, R | 1 |
| Hitti, J | 1 |
| Milewicz, T | 1 |
| Hejnar, J | 1 |
| Jach, R | 1 |
| Jaworowski, AP | 1 |
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| Jasek, M | 1 |
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| Hoosen, AA | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Eradication of H-pylori in Pregnant Patients With Iron Deficiency Anemia Have an Effect on Iron Replacement Therapy?[NCT03347513] | Phase 4 | 150 participants (Anticipated) | Interventional | 2017-11-25 | Recruiting | ||
| Effect of Oral N-Acetyl Cysteine on Pregnancy Outcome After Cervical Cerclage: a Randomized Controlled Trial[NCT00787813] | 100 participants (Anticipated) | Interventional | 2008-06-30 | Completed | |||
| Maternal Effects of Bacterial Vaginosis (BV) Treatment in Pregnancy (Randomized Trial of BV Treatment in Pregnancy)[NCT00153517] | Phase 2 | 126 participants | Interventional | 1999-10-31 | Completed | ||
| Preventing Preterm Birth With Probiotics - Pilot Randomised Trial[NCT02692820] | 304 participants (Actual) | Interventional | 2016-05-31 | Completed | |||
| Study of Antenatal Model to Prevent Preterm Delivery: Early Detection and Treatment of Bacterial Vaginosis[NCT01232192] | 220 participants (Anticipated) | Interventional | 2009-01-31 | Recruiting | |||
| Real-world Performance and Safety of Cerviron® Medical Device in the Treatment of Various Types of Vaginitis[NCT05652959] | 111 participants (Actual) | Observational | 2021-05-20 | Completed | |||
| Phase III Trial of Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission[NCT00021671] | Phase 3 | 3,720 participants | Interventional | Completed | |||
| Clindamycin to Reduce Preterm Birth in a Low Resource Setting: A Randomized Placebo-controlled Trial[NCT01800825] | Phase 4 | 1,726 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| Pregnancy Outcomes Following Preconception Treatment of Asymptomatic Bacterial Vaginosis in an Infertility Population: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.[NCT01322971] | 2 participants (Actual) | Interventional | 2011-02-28 | Terminated (stopped due to Disease prevalence lower than expected in population.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
47 reviews available for metronidazole and Complications, Infectious Pregnancy
| Article | Year |
|---|---|
Maternal Origins of Neonatal Infections: What Do Obstetrician-Gynecologist Should/Could Do?
Topics: Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cesarean Section; Chorioamnionitis; Clindamycin; Com | 2022 |
Screening for Bacterial Vaginosis in Pregnant Adolescents and Women to Prevent Preterm Delivery: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Topics: Anti-Bacterial Agents; Asymptomatic Infections; Clindamycin; Female; Humans; Mass Screening; Metroni | 2020 |
Treatment of bacterial vaginosis before 28 weeks of pregnancy to reduce the incidence of preterm labor.
Topics: Administration, Intravaginal; Administration, Oral; Anti-Bacterial Agents; Clindamycin; Female; Huma | 2019 |
The early use of appropriate prophylactic antibiotics in susceptible women for the prevention of preterm birth of infectious etiology.
Topics: Anti-Bacterial Agents; Clindamycin; Female; Humans; Infant, Newborn; Metronidazole; Pregnancy; Pregn | 2014 |
Diagnostic and therapeutic advancements for aerobic vaginitis.
Topics: Bacteria, Aerobic; Female; Humans; Infant, Newborn; Lactobacillus; Metronidazole; Pregnancy; Pregnan | 2015 |
Treatment of bacterial vaginosis in pregnancy in order to reduce the risk of spontaneous preterm delivery - a clinical recommendation.
Topics: Anti-Bacterial Agents; Clindamycin; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complication | 2016 |
Peripartum Clostridium difficile infection: case series and review of the literature.
Topics: Adult; Anti-Infective Agents; Clostridioides difficile; Enterocolitis, Pseudomembranous; Female; Hum | 2008 |
The Women's Health II Medical Education Network _Part 1: Understanding bacterial vaginosis: diagnosis, treatment, and improved outcomes.
Topics: Adult; Anti-Bacterial Agents; Clindamycin; Female; Humans; Metronidazole; Pregnancy; Pregnancy Compl | 2007 |
Antimicrobial topical agents used in the vagina.
Topics: Administration, Intravaginal; Aminoquinolines; Anti-Infective Agents, Local; Antifungal Agents; Anti | 2011 |
Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies.
Topics: Anti-Infective Agents; Coinfection; Directive Counseling; Female; HIV Infections; Humans; Metronidaz | 2013 |
Bacterial vaginosis and other asymptomatic vaginal infections in pregnancy.
Topics: Adult; Anti-Bacterial Agents; Chlamydia Infections; Comorbidity; Female; Gonorrhea; Humans; Incidenc | 2001 |
Bacterial vaginosis in pregnancy: current findings and future directions.
Topics: Anti-Infective Agents; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious | 2002 |
What have we learned about vaginal infections and preterm birth?
Topics: Anti-Infective Agents; Antitrichomonal Agents; Female; Humans; Metronidazole; National Institutes of | 2003 |
What we have learned from an antibiotic trial in fetal fibronectin positive women.
Topics: Anti-Infective Agents; Drug Therapy, Combination; Erythromycin; Female; Fibronectins; Humans; Metron | 2003 |
Treatment of vaginal infections to prevent preterm birth: a meta-analysis.
Topics: Anti-Infective Agents; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious | 2004 |
Management of vaginitis.
Topics: Administration, Intravaginal; Administration, Oral; Anti-Infective Agents; Antifungal Agents; Family | 2004 |
Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Disease Transmission, Infectious; Female; | 2005 |
[The bacterial vaginosis--treatment problems].
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Bacteria, Anaerobic; Biological | 2007 |
Fertility, sterility, and pregnancy in chronic inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Colitis, Ulcerative; Crohn Disease; Female; Fertility; Humans; Infant, Newb | 1982 |
Prescribing in pregnancy. Infestations.
Topics: Animals; Anthelmintics; Antiprotozoal Agents; Bephenium Compounds; Cestode Infections; Female; Fetus | 1981 |
Bacterial vaginosis in pregnancy: an approach for the 1990s.
Topics: Clindamycin; Female; Fetal Membranes, Premature Rupture; Gestational Age; Humans; Metronidazole; Obs | 1995 |
Bacterial vaginosis: review of treatment options and potential clinical indications for therapy.
Topics: Administration, Topical; Female; Humans; Male; Metronidazole; Pregnancy; Pregnancy Complications, In | 1995 |
Treatment of bacterial vaginosis.
Topics: Adult; Clindamycin; Clinical Trials as Topic; Female; Gels; Humans; Metronidazole; Pregnancy; Pregna | 1994 |
[Bacterial vaginosis II. Related pathology and therapy].
Topics: Anti-Bacterial Agents; Chorioamnionitis; Clindamycin; Endometritis; Female; Humans; Metronidazole; O | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Drug Therapy, Combination; Erythromycin; Female; Humans; Metronidazole; Obstetric Labor, Premature; | 1996 |
Is metronidazole teratogenic? A meta-analysis.
Topics: Case-Control Studies; Cohort Studies; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complicati | 1997 |
Metronidazole. A therapeutic review and update.
Topics: Antitrichomonal Agents; Bacterial Infections; Drug Therapy, Combination; Female; Humans; Metronidazo | 1997 |
Bacterial vaginosis: an update.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Diagnosis, Differential; Female; Humans; | 1998 |
[Bacterial vaginosis].
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Clindamycin; Female; Humans; Metronidazole; Obstetric | 1998 |
Management of bacterial vaginosis.
Topics: Anti-Bacterial Agents; Clindamycin; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complication | 1998 |
Treatment of sexually transmitted bacterial diseases in pregnant women.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Erythromycin; Female; Humans; Metronidaz | 2000 |
Sexually transmitted infections, adverse pregnancy outcome and neonatal infection.
Topics: Diagnosis, Differential; Female; HIV Infections; Humans; Infant, Newborn; Infectious Disease Transmi | 2000 |
Antibiotic selection in obstetrics: making cost-effective choices.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Azithromycin; Carbapenems; Cephalosporins; Clind | 2002 |
Bacterial vaginosis in pregnancy.
Topics: Abortion, Spontaneous; Chorionic Gonadotropin; Cytokines; Female; Humans; Metronidazole; Obstetric L | 2002 |
[Current treatment of bacterial vaginosis].
Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inf | 1999 |
Management of sexually transmissible infections during pregnancy.
Topics: Anti-Bacterial Agents; Candidiasis; Chlamydia Infections; Coitus; Condylomata Acuminata; Corynebacte | 1975 |
[Antibiotics in pregnancy].
Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Cephalosporins; Ch | 1990 |
Bacterial vaginosis: etiology, association with preterm labor, diagnosis, and management.
Topics: Female; Humans; Metronidazole; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications, Infec | 1989 |
Metronidazole, clindamycin, and quinolones.
Topics: 4-Quinolones; Anti-Infective Agents; Bacterial Infections; Clindamycin; Female; Genital Diseases, Fe | 1989 |
Trichomonas vaginalis.
Topics: Carrier State; Female; Humans; Male; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; | 1989 |
[Current therapeutic aspects of Trichomonas vaginalis infections in gynecology].
Topics: Adult; Antitrichomonal Agents; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, In | 1987 |
Metronidazole.
Topics: Breast Feeding; Carcinogens; Female; Humans; Metronidazole; Mutagens; Pregnancy; Pregnancy Complicat | 1987 |
Vaginitis: current microbiologic and clinical concepts.
Topics: Antibody Formation; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Carrier State; Female | 1986 |
Lower genitourinary infections in women.
Topics: Amoxicillin; Anti-Infective Agents, Urinary; Cystitis; Diagnosis, Differential; Drug Combinations; F | 1986 |
[The trichomonads].
Topics: Adult; Female; Gram-Negative Anaerobic Bacteria; Humans; Metronidazole; Microscopy, Phase-Contrast; | 1985 |
Antimicrobial agents in the treatment of obstetric and gynecologic infections.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Cephalosporins; Chloramphenicol; Erythrom | 1974 |
Infectious vaginopathies in pregnancy.
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Glucocorticoids; Gonorrhea; Haemophilus Infect | 1970 |
27 trials available for metronidazole and Complications, Infectious Pregnancy
| Article | Year |
|---|---|
Association between preterm delivery and bacterial vaginosis with or without treatment.
Topics: Adult; Female; Humans; Male; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Prematur | 2019 |
A Phase 3, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of Metronidazole Vaginal Gel 1.3% in the Treatment of Bacterial Vaginosis.
Topics: Administration, Intravaginal; Adult; Anti-Bacterial Agents; Double-Blind Method; Female; Humans; Met | 2015 |
Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis.
Topics: Acetylcysteine; Administration, Oral; Adult; Anti-Infective Agents; Drug Therapy, Combination; Femal | 2009 |
Helicobacter pylori and hyperemesis gravidarum.
Topics: Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Female; Helicobacter Infections; Helicobacter pylor | 2009 |
Comparison of oral and vaginal metronidazole for treatment of bacterial vaginosis in pregnancy: impact on fastidious bacteria.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anti-Bacterial Agents; Bacteria; Female; | 2009 |
Changes in the vaginal microenvironment with metronidazole treatment for bacterial vaginosis in early pregnancy.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Anti-Bacterial Agents; Female; Humans; Me | 2009 |
Pharmacokinetics of metronidazole in pregnant patients with bacterial vaginosis.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; Blood Chemical Analysis; Chrom | 2011 |
Influence of early self-diagnosis and treatment of bacterial vaginosis on preterm birth rate.
Topics: Anti-Infective Agents; Diagnostic Self Evaluation; Female; Gentian Violet; Humans; Hydrogen-Ion Conc | 2012 |
Clinical and cervical cytokine response to treatment with oral or vaginal metronidazole for bacterial vaginosis during pregnancy: a randomized trial.
Topics: Administration, Intravaginal; Administration, Oral; Adolescent; Adult; Cytokines; Dose-Response Rela | 2003 |
Periodontal disease and preterm birth: results of a pilot intervention study.
Topics: Adult; Anti-Infective Agents; Dental Scaling; Double-Blind Method; Feasibility Studies; Female; Huma | 2003 |
Treatment of Trichomonas in pregnancy and adverse outcomes of pregnancy: a subanalysis of a randomized trial in Rakai, Uganda.
Topics: Animals; Antitrichomonal Agents; Birth Rate; Drug Therapy, Combination; Female; Humans; Infant Morta | 2003 |
Time course of the regression of asymptomatic bacterial vaginosis in pregnancy with and without treatment.
Topics: Adult; Anti-Infective Agents; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Inf | 2004 |
Spontaneous resolution of asymptomatic Chlamydia trachomatis in pregnancy.
Topics: Adult; Anti-Infective Agents; Chlamydia Infections; Chlamydia trachomatis; Double-Blind Method; Fema | 2005 |
Routine use of antimicrobials by pregnant Indian women does not improve birth outcome: a randomized controlled trial.
Topics: Adult; Anti-Bacterial Agents; Birth Weight; Cephalexin; Female; Genital Diseases, Female; Gestationa | 2005 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Biomarkers; Birth Weight; Cervix Uteri; Double-B | 2006 |
Clinical trial of interconceptional antibiotics to prevent preterm birth: subgroup analyses and possible adverse antibiotic-microbial interaction.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Azithromycin; Bacterial Infections; Double-Bli | 2007 |
Trichomonas infection in pregnancy--does it affect perinatal outcome?
Topics: Antitrichomonal Agents; Birth Weight; Female; Humans; Infant, Newborn; Metronidazole; Pregnancy; Pre | 1983 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosis.
Topics: Adult; Anti-Bacterial Agents; Antitrichomonal Agents; Body Weight; Double-Blind Method; Erythromycin | 1995 |
Bacterial vaginosis in pregnancy and efficacy of short-course oral metronidazole treatment: a randomized controlled trial.
Topics: Administration, Oral; Adult; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up St | 1994 |
Effect of metronidazole in patients with preterm birth in preceding pregnancy and bacterial vaginosis: a placebo-controlled, double-blind study.
Topics: Adult; Double-Blind Method; Female; Fetal Membranes, Premature Rupture; Humans; Infant, Newborn; Inf | 1994 |
Metronidazole to prevent preterm delivery in pregnant women with asymptomatic bacterial vaginosis. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units.
Topics: Adult; Anti-Infective Agents; Disease-Free Survival; Double-Blind Method; Female; Humans; Infant, Ne | 2000 |
[Therapeutic regimens for treating bacterial vaginosis in pregnant women].
Topics: Administration, Intravaginal; Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Anti-Infective A | 1999 |
Randomized trial of presumptive sexually transmitted disease therapy during pregnancy in Rakai, Uganda.
Topics: Azithromycin; Birth Weight; Cefixime; Drug Therapy, Combination; Endophthalmitis; Female; Folic Acid | 2001 |
[Klion D - possibilities of prophylaxis and treatment during pregnancy].
Topics: Administration, Intravaginal; Animals; Anti-Infective Agents; Cerclage, Cervical; Drug Therapy, Comb | 2001 |
Trichomonas vaginalis. V. Further observations on metronidazole (Flagyl) (including infant follow-up).
Topics: Abnormalities, Drug-Induced; Adult; Clinical Trials as Topic; Drug Resistance, Microbial; Female; Fe | 1965 |
Leucorrhoea due to Trichomonas vaginalis--clinical trial with hamycin.
Topics: Adolescent; Adult; Antifungal Agents; Arsenicals; Clinical Trials as Topic; Female; Humans; Leukorrh | 1966 |
[The use of a new drug (Deflamon) in the treatment of vaginal trichomoniasis].
Topics: Female; Humans; Metronidazole; Muramidase; Pregnancy; Pregnancy Complications, Infectious; Trichomon | 1968 |
94 other studies available for metronidazole and Complications, Infectious Pregnancy
| Article | Year |
|---|---|
Prenatal chlamydial, gonococcal, and trichomonal screening in the Democratic Republic of Congo for case detection and management.
Topics: Adult; Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Cross-Secti | 2020 |
Does Partner Treatment Impact on Bacterial Vaginosis Cure?
Topics: Double-Blind Method; Female; Humans; Male; Metronidazole; Pregnancy; Pregnancy Complications, Infect | 2021 |
The safety of metronidazole in pregnancy.
Topics: Anti-Bacterial Agents; Female; Humans; Infant, Newborn; Metronidazole; Pregnancy; Pregnancy Complica | 2021 |
Use of antibiotics during pregnancy and risk of spontaneous abortion.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Bacterial Agents; Case-Control Studies; Cohort Studie | 2017 |
Sonographic detection of an infected maternal urachal cyst during pregnancy.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; | 2018 |
Topics: Amniotic Fluid; Anti-Bacterial Agents; Extraembryonic Membranes; Female; Humans; Metronidazole; Myco | 2018 |
Resolution of intra-amniotic sludge after antibiotic administration in a patient with short cervix and recurrent mid-trimester loss.
Topics: Abortion, Habitual; Adult; Anti-Bacterial Agents; Cerclage, Cervical; Cervix Uteri; Chorioamnionitis | 2019 |
Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes.
Topics: Adult; Amniocentesis; Amniotic Fluid; Anti-Bacterial Agents; Biomarkers; Ceftriaxone; Chorioamnionit | 2019 |
Successful treatment of acute uncomplicated appendicitis in pregnancy with intravenous antibiotics.
Topics: Administration, Oral; Adult; Amoxicillin-Potassium Clavulanate Combination; Appendicitis; Female; Ge | 2013 |
Helicobacter pylori and anemia with pregnancy.
Topics: Adult; Ampicillin; Anemia, Iron-Deficiency; Anti-Infective Agents; Drug Therapy, Combination; Female | 2014 |
Evaluation of the quality of antenatal care using electronic health record information in family medicine clinics of Mexico City.
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Electronic Health Records; Family Practice; Female; | 2014 |
Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women.
Topics: Adolescent; Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Ethylene Glycols; Female; Human | 2015 |
Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Canada; Candidiasis, Vulvovaginal; Clindamycin; Female | 2015 |
A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM.
Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Chorioamnionitis; Clarithromycin; Drug Therapy, Combinati | 2016 |
[Trichomoniasis].
Topics: Antiprotozoal Agents; DNA, Protozoan; Female; Humans; Male; Metronidazole; Polymerase Chain Reaction | 2016 |
The treatment of bacterial vaginosis in pregnancy with clindamycin to reduce the risk of infection-related preterm birth: a response to the Danish Society of Obstetrics and Gynecology guideline group's clinical recommendations.
Topics: Abortion, Spontaneous; Anti-Bacterial Agents; Clindamycin; Female; Humans; Infant, Low Birth Weight; | 2017 |
The effect of body mass index on therapeutic response to bacterial vaginosis in pregnancy.
Topics: Adult; Antiprotozoal Agents; Body Mass Index; Female; Humans; Metronidazole; Obesity, Morbid; Overwe | 2008 |
[Vaginal infections associated with bacterial vaginosis and periodontal disease--effective diagnostic and therapeutic possibilities].
Topics: Anti-Bacterial Agents; Clindamycin; Congresses as Topic; Drug Therapy, Combination; Female; HIV Infe | 2008 |
Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy.
Topics: Adult; Anti-Infective Agents; Female; Humans; Metronidazole; Mycoplasma hominis; Mycoplasma Infectio | 2009 |
[Bacterial vaginosis and preterm delivery risk].
Topics: Administration, Intravaginal; Adult; Anti-Bacterial Agents; Causality; Chi-Square Distribution; Como | 2010 |
Role of Helicobacter pylori in the pathogenesis of hyperemesis gravidarum.
Topics: Adult; Ampicillin; Anti-Infective Agents; Anti-Ulcer Agents; Antibodies, Bacterial; Enzyme-Linked Im | 2011 |
A case of massive vulvar oedema due to septic pubic symphysitis complicating pregnancy.
Topics: Adult; Anti-Bacterial Agents; C-Reactive Protein; Ceftriaxone; Edema; Female; Fever; Gentamicins; Hu | 2010 |
Effective of metronidazole to bacterial flora in vagina and the impact of microbes on live birth rate during intracytoplasmic sperm injection (ICSI).
Topics: Adult; Anti-Infective Agents; Birth Rate; Embryo Transfer; Female; Humans; Live Birth; Metronidazole | 2011 |
Bacterial vaginosis in threatened preterm, preterm and term labour.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Female; Gestational Age; Humans; Infant, Newborn; Infant, | 2010 |
Treatment of bacterial vaginosis does not reduce preterm birth among high-risk asymptomatic women in fetal fibronectin positive patients.
Topics: Adult; Anti-Infective Agents; Apgar Score; Birth Weight; Chi-Square Distribution; Enzyme-Linked Immu | 2011 |
Pregnancy complicated by recurrent brain abscess after extraction of an infected tooth.
Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Brain Abscess; Cefotaxime; Cesarean Section; Dexameth | 2011 |
MRSA bacteraemia after caesarean section wound infection: when screening is missed and things go wrong.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Cefuroxime; Cesarean Sec | 2012 |
Trichomonas vaginalis infection in a premature newborn.
Topics: Animals; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infectious Disease T | 2002 |
Metronidazole and pregnancy.
Topics: Administration, Oral; Administration, Topical; Adult; Anti-Bacterial Agents; Bacterial Infections; F | 2002 |
Bacterial vaginosis in pregnancy: diagnosis and treatment practices of physicians in San Diego, California, 1999.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; California; Clindamycin; Cross-Sectional Studies; Fema | 2003 |
FURTHER STUDIES IN TREATMENT OF FEMALE AND MALE TRICHOMONIASIS WITH METRONIDAZOLE.
Topics: Antiprotozoal Agents; Candidiasis, Vulvovaginal; Carrier State; Communicable Diseases; Epidemiology; | 1963 |
THE EFFECT OF METRONIDAZOLE ON VAGINAL MICROBIOLOGY AND MATERNAL AND NEONATAL HEMATOLOGY.
Topics: Adolescent; Blood Cell Count; Candida; Corynebacterium; Female; Hematology; Humans; Hydrogen-Ion Con | 1964 |
[DOES VAGINAL CANDIDIASIS HAVE AN HORMONAL ETIOLOGY?].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Candidiasis; Candidiasis, Vulvovaginal; Female; | 1964 |
METRONIDAZOLE TREATMENT OF TRICHOMONIASIS IN PREGNANCY.
Topics: Communicable Diseases; Congenital Abnormalities; Drug Therapy; Female; Fetal Death; Humans; Infant, | 1965 |
Cost-effectiveness of screening and treatment for bacterial vaginosis in early pregnancy among women at low risk for preterm birth.
Topics: Anti-Infective Agents; Clindamycin; Cost-Benefit Analysis; Decision Trees; Diagnosis-Related Groups; | 2004 |
Is a change in the vaginal flora associated with an increased risk of preterm birth?
Topics: Administration, Intravaginal; Adult; Case-Control Studies; Cohort Studies; Confidence Intervals; Esc | 2005 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET Study by Shennan et al.
Topics: Anti-Infective Agents; Biomarkers; Female; Fibronectins; Glycoproteins; Humans; Metronidazole; Obste | 2006 |
A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET study.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biomarkers; Clindamycin; Female; Fibronectins; Glycopr | 2006 |
Comment on "Pregnancy outcome after early detection of bacterial vaginosis" [Eur. J. Obstet. Gynecol. Reprod. Biol. 128 (2006) 40-45].
Topics: Adult; Animals; Antiprotozoal Agents; Clindamycin; Female; Humans; Infant, Newborn; Metronidazole; P | 2007 |
Antibiotics for the prevention of preterm birth.
Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Clindamycin; Female; Humans; Meta-Analysis as Topic; | 2008 |
Toxicologic evaluation of metronidazole with particular reference to carcinogenic, mutagenic, and teratogenic potential.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Crohn Disease; Female; Follow-Up Studies; Humans; | 1983 |
ABC of sexually transmitted diseases. Vaginal discharge--management.
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Humans; Leukorrhea; Male; Metronidazole; Pessa | 1983 |
Local application of metronidazole in vaginal ovules for treatment of trichomoniasis.
Topics: Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Suppositories; Tricho | 1984 |
Conventional therapy of trichomoniasis.
Topics: Antitrichomonal Agents; Female; Gastrointestinal Diseases; Humans; Metronidazole; Ornidazole; Pregna | 1983 |
Amoebic liver abscess in pregnancy. Case reports.
Topics: Adult; Drainage; Female; Humans; Liver Abscess, Amebic; Metronidazole; Pregnancy; Pregnancy Complica | 1984 |
Septicemia due to Mycoplasma hominis.
Topics: Amoxicillin; Ampicillin; Clindamycin; Doxycycline; Female; Humans; Male; Metronidazole; Mycoplasma I | 1983 |
[Metronidazole in the treatment and prevention of infections in gynecology and obstetrics].
Topics: Bacterial Infections; Biotransformation; Female; Humans; Maternal-Fetal Exchange; Metabolic Clearanc | 1983 |
Midline facial defect as a teratogenic effect of metronidazole.
Topics: Abnormalities, Drug-Induced; Amebiasis; Child, Preschool; Face; Female; Humans; Infant; Infant, Newb | 1982 |
Diagnosis and treatment of vaginal discharge in pregnancy.
Topics: Candidiasis; Female; Humans; Leukorrhea; Metronidazole; Pregnancy; Pregnancy Complications, Infectio | 1980 |
Pharmacokinetics of Metronidazole in pregnant women.
Topics: Blood Proteins; Female; Humans; Kinetics; Metronidazole; Pregnancy; Pregnancy Complications, Infecti | 1981 |
Metronidazole during pregnancy.
Topics: Adrenal Gland Neoplasms; Adult; Female; Gardnerella vaginalis; Humans; Infant, Newborn; Male; Metron | 1995 |
First antenatal visits and metronidazole.
Topics: Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, | 1997 |
The weak cervix: failing to keep the baby in or infection out?
Topics: Adult; Anti-Bacterial Agents; Female; Hospitalization; Humans; Metronidazole; Pregnancy; Pregnancy C | 1998 |
Use of metronidazole during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anti-Infective Agents; Contraindications; Female; Hu | 1999 |
Screening for bacterial vaginosis.
Topics: Anti-Infective Agents; Female; Humans; Mass Screening; Metronidazole; Obstetric Labor, Premature; Pr | 1998 |
Safety of metronidazole during pregnancy: a cohort study of risk of congenital abnormalities, preterm delivery and low birth weight in 124 women.
Topics: Abnormalities, Drug-Induced; Adult; Anti-Infective Agents; Cohort Studies; Female; Humans; Infant, L | 1999 |
National guideline for the management of bacterial vaginosis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases).
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Drug Administration Schedule; Fema | 1999 |
Drugs for sexually transmitted infections.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Azithromycin; Chlamydia | 1999 |
Does oral metronidazole prevent preterm delivery in normal-risk pregnant women with asymptomatic bacterial vaginosis (BV)?
Topics: Anti-Infective Agents; Delivery, Obstetric; Double-Blind Method; Female; Gestational Age; Humans; In | 2000 |
Abnormal vaginal flora, cervical length and preterm birth.
Topics: Cervical Ripening; Female; Gestational Age; Humans; Metronidazole; Obstetric Labor, Premature; Predi | 2000 |
Data on HIV infection in women expands.
Topics: Anti-Bacterial Agents; Azithromycin; Cefixime; Drug Administration Schedule; Drug Therapy, Combinati | 1999 |
Prevalence of bacterial vaginosis in antenatal women.
Topics: Adult; Anti-Infective Agents; Female; Humans; India; Metronidazole; Pregnancy; Pregnancy Complicatio | 2001 |
[Treatment of trichomonas vaginitis in pregnant women].
Topics: Antitrichomonal Agents; Evidence-Based Medicine; Female; Humans; Metronidazole; Pregnancy; Pregnancy | 2002 |
Bacterial vaginosis during pregnancy. Should we screen for and treat it?
Topics: Anti-Infective Agents; Clindamycin; Female; Humans; Mass Screening; Metronidazole; Pregnancy; Pregna | 2002 |
Metronidazole treatment in pregnancy.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Drug Evaluation; Female; Humans; Metronidazole; P | 1978 |
Intravenous metronidazole in amoebic enterocolitis.
Topics: Adult; Dysentery, Amebic; Female; Humans; Infusions, Parenteral; Metronidazole; Pregnancy; Pregnancy | 1976 |
Metronidazole therapy of anaerobic bacteremia, meningitis, and brain abscess.
Topics: Adult; Anaerobiosis; Bacterial Infections; Bacteroides fragilis; Bacteroides Infections; Brain Absce | 1979 |
Unusual presentation of primary amoebic meningoencephalitis--a serious diagnostic and therapeutic problem.
Topics: Adult; Amebiasis; Chloramphenicol; Drug Therapy, Combination; Female; Humans; Isoniazid; Meningoence | 1978 |
Single-dose metronidazole for trichomonal vaginitis: patient and consort.
Topics: Drug Administration Schedule; Female; Humans; Male; Metronidazole; Pregnancy; Pregnancy Complication | 1978 |
Trichomoniasis treated with a single dose of benzoylmetronidazole.
Topics: Adolescent; Adult; Female; Humans; Metronidazole; Middle Aged; Pregnancy; Pregnancy Complications, I | 1978 |
[Trichomoniasis in the newborn (author's transl)].
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metronidazole; Pregnancy; Pregnancy Comp | 1977 |
Amebic abscess of the liver and spleen in pregnancy and the puerperium.
Topics: Adolescent; Adult; Amebiasis; Chloroquine; Emetine; Female; Humans; Infant, Newborn; Liver Abscess, | 1975 |
Paromomycin in the treatment of mild-to-moderate intestinal amebiasis.
Topics: Abnormalities, Drug-Induced; Dysentery, Amebic; Female; Humans; Metronidazole; Paromomycin; Pregnanc | 1992 |
[Diagnosis of infection in at risk pregnancies].
Topics: Bacterial Infections; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; | 1991 |
Trichomoniasis: trends in diagnosis and management.
Topics: Drug Resistance; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Latex Fixa | 1991 |
Clindamycin versus metronidazole in the treatment of bacterial vaginosis.
Topics: Bacterial Infections; Clindamycin; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications | 1989 |
[Problems of antiparasitic therapy in pregnancy].
Topics: Antiprotozoal Agents; Chloroquine; Female; Humans; Metronidazole; Parasitic Diseases; Pregnancy; Pre | 1988 |
Antiparasitic agents in pregnancy.
Topics: Amebiasis; Female; Helminthiasis; Humans; Malaria; Metronidazole; Parasitic Diseases; Pregnancy; Pre | 1986 |
[Bacterial vaginitis. Microbiology, diagnosis, therapy and complications].
Topics: Anti-Bacterial Agents; Chlamydia Infections; Female; Gardnerella vaginalis; Gonorrhea; Haemophilus I | 1985 |
Management of giardiasis.
Topics: Diarrhea; Disease Outbreaks; Female; Furazolidone; Giardiasis; Humans; Infant, Newborn; Intestinal D | 1985 |
Hepatic amebic abscess. Unresponsiveness to combination of metronidazole and surgical drainage.
Topics: Administration, Oral; Adult; Chloroquine; Drainage; Emetine; Female; Humans; Injections, Intramuscul | 1974 |
The principles of prevention of avoidable maternal death. A study of 538 consecutive maternal deaths in the obstetric unit, King Edward 8th Hospital, Durban, 1953-1971.
Topics: Anesthesia, Inhalation; Anesthesia, Obstetrical; Cesarean Section; Dysentery, Amebic; Emergencies; F | 1973 |
Neonatal Trichomonas vaginalis: report of three cases and review of the literature.
Topics: Age Factors; Culture Media; Feces; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; | 1974 |
[Epidemiology, pathology and clinical aspects of trichomonas vaginalis infection].
Topics: Age Factors; Candidiasis; Carcinoma in Situ; Chronic Disease; Fallopian Tubes; Female; History, 19th | 1973 |
Vaginitis.
Topics: Adolescent; Candida albicans; Candidiasis, Vulvovaginal; Child; Corynebacterium Infections; Female; | 1974 |
[Case report on the diagnosis of trichomonas ulcers].
Topics: Adult; Diagnosis, Differential; Female; Humans; Metronidazole; Penicillins; Pregnancy; Pregnancy Com | 1973 |
[Trichopol treatment of pregnant women suffering from genital trichomoniasis].
Topics: Animals; Female; Fetus; Humans; Metronidazole; Mice; Pregnancy; Pregnancy Complications, Infectious; | 1973 |
[Treatment of trichomonas vaginitis in pregnant with metronidazole "Polfa"].
Topics: Female; Follow-Up Studies; Humans; Infant, Newborn; Metronidazole; Pregnancy; Pregnancy Complication | 1969 |
[Significance of the treatment of trichomoniasis in gynecology and obstetrics].
Topics: Abortion, Spontaneous; Antiprotozoal Agents; Antitrichomonal Agents; Appendicitis; Female; Humans; M | 1969 |
[Trichomonacide therapy in pregnancy. On the use of metronidazole].
Topics: Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Trichomonas Infection | 1969 |
[Trichomoniasis in pregnant women and its treatment with RP 8823].
Topics: Adult; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Trichomonas Va | 1964 |
Metronidazole in pregnancy.
Topics: Adult; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Trichomonas Va | 1966 |
Pregnancy, trichomoniasis, and metronidazole. A novel dose schedule.
Topics: Adult; Female; Fetus; Humans; Metronidazole; Pregnancy; Pregnancy Complications, Infectious; Trichom | 1966 |
[Treatment of trichomonas vaginitis in the pregnant woman with Metronidazole (8 823 RP). Absence of teratogenic effects].
Topics: Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Metronidazole; Pregnancy; Pregnancy Compli | 1966 |