metronidazole has been researched along with Communicable Diseases, Emerging in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Communicable Diseases, Emerging: Infectious diseases that are novel in their outbreak ranges (geographic and host) or transmission mode.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calfee, DP | 1 |
| Gutiérrez-Cisneros, MJ | 1 |
| Martín-Rabadán, P | 1 |
| Menchén, L | 1 |
| García-Lechuz, JM | 1 |
| Fuentes, I | 1 |
| Gárate, T | 1 |
| Bouza, E | 1 |
| Andiran, N | 1 |
| Acikgoz, ZC | 1 |
| Turkay, S | 1 |
| Andiran, F | 1 |
2 reviews available for metronidazole and Communicable Diseases, Emerging
| Article | Year |
|---|---|
Clostridium difficile: a reemerging pathogen.
Topics: Aged; Anti-Bacterial Agents; Clostridioides difficile; Colectomy; Communicable Diseases, Emerging; C | 2008 |
[Autochthonous amebic liver abscess in Spain: an emerging disease? Case report and description of a PCR-based diagnostic test].
Topics: Adult; Aged; Amebicides; Animals; Antibodies, Protozoan; Chloroquine; Combined Modality Therapy; Com | 2009 |
1 other study available for metronidazole and Communicable Diseases, Emerging
| Article | Year |
|---|---|
Blastocystis hominis--an emerging and imitating cause of acute abdomen in children.
Topics: Abdomen, Acute; Animals; Blastocystis hominis; Blastocystis Infections; Child; Communicable Diseases | 2006 |