Page last updated: 2024-10-31

metronidazole and Colorectal Neoplasms

metronidazole has been researched along with Colorectal Neoplasms in 27 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"The aim of our study was to evaluate the impact of metronidazole (MTZ) on DLD-1 colorectal cancer cell (CRC) line."7.79Metronidazole decreases viability of DLD-1 colorectal cancer cell line. ( Car, H; Cechowska-Pasko, M; Krętowski, R; Sadowska, A; Szynaka, B, 2013)
"Fifteen to 25% of patients with colorectal cancer have combined liver metastases at the time of diagnosis, whereas an additional 15 to 25% will develop liver metastases after curative resection of primary colorectal cancer, with the vast majority (80-90%) of liver metastases unresponsive to curative resection at first."7.30A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer. ( Dong, DH; Gao, RQ; Ji, G; Li, XH; Mo, ZC; Wang, WD; Yang, XS; Yu, PF; Zhou, HK, 2023)
"The aim of our study was to evaluate the impact of metronidazole (MTZ) on DLD-1 colorectal cancer cell (CRC) line."3.79Metronidazole decreases viability of DLD-1 colorectal cancer cell line. ( Car, H; Cechowska-Pasko, M; Krętowski, R; Sadowska, A; Szynaka, B, 2013)
"Fifteen to 25% of patients with colorectal cancer have combined liver metastases at the time of diagnosis, whereas an additional 15 to 25% will develop liver metastases after curative resection of primary colorectal cancer, with the vast majority (80-90%) of liver metastases unresponsive to curative resection at first."3.30A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer. ( Dong, DH; Gao, RQ; Ji, G; Li, XH; Mo, ZC; Wang, WD; Yang, XS; Yu, PF; Zhou, HK, 2023)
"Biofilms on oral squamous cell carcinomas are enriched with anaerobic periodontal pathogens, including F."2.72Fusobacterium nucleatum and oral cancer: a critical review. ( Craig, SG; James, JA; Linden, GJ; Lundy, FT; McIlvanna, E, 2021)
"We compared postoperative wound infection rates in 221 colorectal surgery patients randomized to receive systemic gentamicin/metronidazole with (Group I, n = 107) or without (Group II, n = 114) the gentamicin-collagen sponge."2.68Prevention of wound infection in elective colorectal surgery by local application of a gentamicin-containing collagen sponge. ( Nijhuis, PH; Rutten, HJ, 1997)
"The files of individuals who underwent colorectal cancer surgery at the University Hospital Brandenburg an der Havel (Germany) between 2009 and 2017 were analyzed."1.91Optimal timing for antimicrobial prophylaxis to reduce surgical site infections: a retrospective analysis of 531 patients. ( Haller, IE; Heisler, S; Helmke, C; Hunger, R; Kirbach, J; Kobelt, E; Lünse, S; Mantke, R; Meyer, J; Paasch, C; Schildberg, C, 2023)
"OAs significantly reduce SSI in colorectal cancer surgery."1.91Preoperative oral antibiotic administration in patients undergoing curative resection with stoma creation for colorectal cancer: effectiveness in preventing surgical site infection and the possibility of peristomal candidiasis induced by enterobacterial a ( Arita, T; Fujiwara, H; Ikoma, H; Kiuchi, J; Konishi, H; Kubota, T; Kuriu, Y; Morimura, R; Nanishi, K; Ohashi, T; Otsuji, E; Shimizu, H; Shiozaki, A; Takaki, W; Yamamoto, Y, 2023)
"Metronidazole (MTZ) is a drug potentially used for the treatment of intestinal infections, namely, the ones caused by colorectal surgery."1.72Metronidazole Delivery Nanosystem Able To Reduce the Pathogenicity of Bacteria in Colorectal Infection. ( Araújo, A; Leão, P; Martins, A; Neves, NM; Oliveira, A; Reis, RL; Rodrigues, LC; Silva, CS, 2022)
" Severe obese patients need higher dosage of antibiotics."1.34[Use of antibiotics in colorectal surgery in Denmark]. ( Frimodt-Møller, N; Jensen, TG; Madsen, H; Pedersen, C; Qvist, N; Salomon, S, 2007)
"A model of colorectal cancer liver metastases in male inbred CBA mice was used."1.31Interstitial laser hyperthermia for colorectal liver metastases: the effect of thermal sensitization and the use of a cylindrical diffuser tip on tumor necrosis. ( Christophi, C; Malcontenti-Wilson, C; Muralidharan, V, 2002)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's11 (40.74)18.2507
2000's4 (14.81)29.6817
2010's4 (14.81)24.3611
2020's7 (25.93)2.80

Authors

AuthorsStudies
McIlvanna, E1
Linden, GJ1
Craig, SG1
Lundy, FT1
James, JA1
Oliveira, A1
Araújo, A1
Rodrigues, LC1
Silva, CS1
Reis, RL1
Neves, NM1
Leão, P1
Martins, A1
Paasch, C1
Schildberg, C1
Lünse, S1
Heisler, S1
Meyer, J1
Kirbach, J1
Kobelt, E1
Hunger, R1
Haller, IE1
Helmke, C1
Mantke, R1
Kiuchi, J1
Kuriu, Y1
Arita, T1
Shimizu, H1
Nanishi, K1
Takaki, W1
Ohashi, T1
Konishi, H1
Yamamoto, Y1
Morimura, R1
Shiozaki, A1
Ikoma, H1
Kubota, T1
Fujiwara, H1
Otsuji, E1
Wang, M1
Li, Y1
Yang, X1
Liu, Z1
Wang, K1
Gong, D1
Li, J1
Gao, RQ1
Mo, ZC1
Zhou, HK1
Yu, PF1
Wang, WD1
Dong, DH1
Yang, XS1
Li, XH1
Ji, G1
Sethi, S1
Puri, A1
Sachdeva, S1
Dalal, A1
Bullman, S1
Pedamallu, CS1
Sicinska, E1
Clancy, TE1
Zhang, X1
Cai, D1
Neuberg, D1
Huang, K1
Guevara, F1
Nelson, T1
Chipashvili, O1
Hagan, T1
Walker, M1
Ramachandran, A1
Diosdado, B1
Serna, G1
Mulet, N1
Landolfi, S1
Ramon Y Cajal, S1
Fasani, R1
Aguirre, AJ1
Ng, K1
Élez, E1
Ogino, S1
Tabernero, J1
Fuchs, CS1
Hahn, WC1
Nuciforo, P1
Meyerson, M1
Sadowska, A1
Krętowski, R1
Szynaka, B1
Cechowska-Pasko, M1
Car, H1
Hata, H1
Yamaguchi, T2
Hasegawa, S1
Nomura, A1
Hida, K1
Nishitai, R1
Yamanokuchi, S1
Yamanaka, T1
Sakai, Y1
Ikeda, A1
Konishi, T1
Ueno, M1
Fukunaga, Y1
Nagayama, S1
Fujimoto, Y1
Akiyoshi, T1
Yabata, E1
Okabe, S1
Endo, M1
Muralidharan, V1
Malcontenti-Wilson, C1
Christophi, C1
Espin-Basany, E1
Sanchez-Garcia, JL1
Lopez-Cano, M1
Lozoya-Trujillo, R1
Medarde-Ferrer, M1
Armadans-Gil, L1
Alemany-Vilches, L1
Armengol-Carrasco, M1
Salomon, S1
Jensen, TG1
Qvist, N1
Frimodt-Møller, N1
Pedersen, C1
Madsen, H1
Rau, BK1
Harikrishnan, KM1
Krishna, S1
AhChong, K1
Yip, AW1
Lee, FC1
Chiu, KM1
Menzel, J1
Bauer, J1
von Pritzbuer, E1
Klempa, I1
Rutten, HJ1
Nijhuis, PH1
Zelenitsky, SA1
Silverman, RE1
Duckworth, H1
Harding, GK1
Löhde, E1
Scholz, L1
Gemperle, A1
Langmark, H1
Hopfenmüller, W1
Abri, O1
Kraas, E1
Lumley, JW1
Siu, SK1
Pillay, SP1
Stitz, R1
Kemp, RJ1
Faoagali, J1
Nathanson, LK1
White, S1
Pacelli, F1
Brisinda, G1
Bellantone, R1
Doglietto, GB1
Crucitti, F1
Tsimoyiannis, EC1
Paizis, JB1
Kabbani, K1
Lekkas, ET1
Floras, GA1
Boulis, SA1
Nøhr, M1
Andersen, JC1
Juul-Jensen, KE1
Sachar, DB1
Lewis, RT1
Goodall, RG1
Marien, B1
Lloyd-Smith, W1
Park, M1
Wiegand, FM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Rectal Microbiome Variability Among Rectal Cancer Cohorts Including Complete Clinical Responders, Pathologic Responders, and Early Recurrence[NCT04223102]40 participants (Anticipated)Interventional2020-02-18Active, not recruiting
PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery[NCT03574090]Phase 4268 participants (Actual)Interventional2020-10-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for metronidazole and Colorectal Neoplasms

ArticleYear
Fusobacterium nucleatum and oral cancer: a critical review.
    BMC cancer, 2021, Nov-13, Volume: 21, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Cell Movement; Cell Proliferation; Col

2021
Fusobacterium nucleatum and oral cancer: a critical review.
    BMC cancer, 2021, Nov-13, Volume: 21, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Cell Movement; Cell Proliferation; Col

2021

Trials

15 trials available for metronidazole and Colorectal Neoplasms

ArticleYear
A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer.
    Trials, 2023, Dec-04, Volume: 24, Issue:1

    Topics: Colorectal Neoplasms; Double-Blind Method; Humans; Incidence; Liver Neoplasms; Metronidazole; Prospe

2023
A prospective, single-centre, randomized, double-blind controlled study protocol to study whether long-term oral metronidazole can effectively reduce the incidence of postoperative liver metastasis in patients with colorectal cancer.
    Trials, 2023, Dec-04, Volume: 24, Issue:1

    Topics: Colorectal Neoplasms; Double-Blind Method; Humans; Incidence; Liver Neoplasms; Metronidazole; Prospe

2023
Oral and Parenteral Versus Parenteral Antibiotic Prophylaxis in Elective Laparoscopic Colorectal Surgery (JMTO PREV 07-01): A Phase 3, Multicenter, Open-label, Randomized Trial.
    Annals of surgery, 2016, Volume: 263, Issue:6

    Topics: Aged; Antibiotic Prophylaxis; Cefmetazole; Colorectal Neoplasms; Elective Surgical Procedures; Femal

2016
Oral and Parenteral Versus Parenteral Antibiotic Prophylaxis in Elective Laparoscopic Colorectal Surgery (JMTO PREV 07-01): A Phase 3, Multicenter, Open-label, Randomized Trial.
    Annals of surgery, 2016, Volume: 263, Issue:6

    Topics: Aged; Antibiotic Prophylaxis; Cefmetazole; Colorectal Neoplasms; Elective Surgical Procedures; Femal

2016
Randomized clinical trial of oral and intravenous versus intravenous antibiotic prophylaxis for laparoscopic colorectal resection.
    The British journal of surgery, 2016, Volume: 103, Issue:12

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anastomotic Leak; Anti-Bacterial Agents; Antib

2016
Randomized clinical trial of oral and intravenous versus intravenous antibiotic prophylaxis for laparoscopic colorectal resection.
    The British journal of surgery, 2016, Volume: 103, Issue:12

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anastomotic Leak; Anti-Bacterial Agents; Antib

2016
A prospective, randomized clinical trial of preoperative bowel preparation for elective colorectal surgery--comparison among oral, systemic, and intraoperative luminal antibacterial preparations.
    Journal of medical and dental sciences, 1997, Volume: 44, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophy

1997
A prospective, randomized clinical trial of preoperative bowel preparation for elective colorectal surgery--comparison among oral, systemic, and intraoperative luminal antibacterial preparations.
    Journal of medical and dental sciences, 1997, Volume: 44, Issue:4

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophy

1997
Prospective, randomised study on antibiotic prophylaxis in colorectal surgery. Is it really necessary to use oral antibiotics?
    International journal of colorectal disease, 2005, Volume: 20, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic

2005
Prospective, randomised study on antibiotic prophylaxis in colorectal surgery. Is it really necessary to use oral antibiotics?
    International journal of colorectal disease, 2005, Volume: 20, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic

2005
Comparison of prophylactic ampicillin/sulbactam with gentamicin and metronidazole in elective colorectal surgery: a randomized clinical study.
    The Journal of hospital infection, 1994, Volume: 27, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Colon; Colorectal Neoplasms; Colostomy; Drug Therapy, Co

1994
Comparison of prophylactic ampicillin/sulbactam with gentamicin and metronidazole in elective colorectal surgery: a randomized clinical study.
    The Journal of hospital infection, 1994, Volume: 27, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Colon; Colorectal Neoplasms; Colostomy; Drug Therapy, Co

1994
[Perioperative use of ampicillin/sulbactam, cefoxitin and piperacillin/ metronidazole in elective colon and rectal surgery. A prospective randomized quality assurance study of 422 patients].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1993, Volume: 64, Issue:8

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cefoxitin; Colitis, Ulcerative; Colon

1993
[Perioperative use of ampicillin/sulbactam, cefoxitin and piperacillin/ metronidazole in elective colon and rectal surgery. A prospective randomized quality assurance study of 422 patients].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1993, Volume: 64, Issue:8

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Cefoxitin; Colitis, Ulcerative; Colon

1993
Prevention of wound infection in elective colorectal surgery by local application of a gentamicin-containing collagen sponge.
    The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1997, Issue:578

    Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Collagen; Colorectal

1997
Prevention of wound infection in elective colorectal surgery by local application of a gentamicin-containing collagen sponge.
    The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1997, Issue:578

    Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Collagen; Colorectal

1997
A prospective, randomized, double-blind studyof single high dose versus multiple standard dose gentamicin both in combination withmetronidazole for colorectal surgicalprophylaxis.
    The Journal of hospital infection, 2000, Volume: 46, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Colorectal Neoplasms; Di

2000
A prospective, randomized, double-blind studyof single high dose versus multiple standard dose gentamicin both in combination withmetronidazole for colorectal surgicalprophylaxis.
    The Journal of hospital infection, 2000, Volume: 46, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Colorectal Neoplasms; Di

2000
[Comparative analysis of mezlocillin/metronidazole and amoxicillin/clavulanic acid as "one shot" preventive antibiotic administration in colorectal interventions].
    Zentralblatt fur Chirurgie, 1992, Volume: 117, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acid

1992
[Comparative analysis of mezlocillin/metronidazole and amoxicillin/clavulanic acid as "one shot" preventive antibiotic administration in colorectal interventions].
    Zentralblatt fur Chirurgie, 1992, Volume: 117, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Clavulanic Acid; Clavulanic Acid

1992
Single dose ceftriaxone as prophylaxis for sepsis in colorectal surgery.
    The Australian and New Zealand journal of surgery, 1992, Volume: 62, Issue:4

    Topics: Cefazolin; Ceftriaxone; Colon; Colorectal Neoplasms; Double-Blind Method; Female; Humans; Male; Metr

1992
Single dose ceftriaxone as prophylaxis for sepsis in colorectal surgery.
    The Australian and New Zealand journal of surgery, 1992, Volume: 62, Issue:4

    Topics: Cefazolin; Ceftriaxone; Colon; Colorectal Neoplasms; Double-Blind Method; Female; Humans; Male; Metr

1992
Single dose imipenem-cilastatin compared with three doses of cefuroxime and metronidazole as prophylaxis in elective colorectal surgery: a prospective randomized study.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefuroxime; Cilastatin; Colorectal Neoplasms;

1991
Single dose imipenem-cilastatin compared with three doses of cefuroxime and metronidazole as prophylaxis in elective colorectal surgery: a prospective randomized study.
    Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefuroxime; Cilastatin; Colorectal Neoplasms;

1991
Short-term antibiotic prophylaxis in elective colorectal surgery.
    Chemotherapy, 1991, Volume: 37, Issue:1

    Topics: Aged; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Ceftriaxone; Colorectal Neoplasms; Cost

1991
Short-term antibiotic prophylaxis in elective colorectal surgery.
    Chemotherapy, 1991, Volume: 37, Issue:1

    Topics: Aged; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Ceftriaxone; Colorectal Neoplasms; Cost

1991
Prophylactic single-dose fosfomycin and metronidazole compared with neomycin, bacitracin, metronidazole and ampicillin in elective colorectal operations.
    Acta chirurgica Scandinavica, 1990, Volume: 156, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Bacitracin; Colorectal Neoplasms; Dose-Response Relation

1990
Prophylactic single-dose fosfomycin and metronidazole compared with neomycin, bacitracin, metronidazole and ampicillin in elective colorectal operations.
    Acta chirurgica Scandinavica, 1990, Volume: 156, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Bacitracin; Colorectal Neoplasms; Dose-Response Relation

1990
Is neomycin necessary for bowel preparation in surgery of the colon? Oral neomycin plus erythromycin versus erythromycin-metronidazole.
    Canadian journal of surgery. Journal canadien de chirurgie, 1989, Volume: 32, Issue:4

    Topics: Administration, Oral; Aged; Bacteria, Anaerobic; Clinical Trials as Topic; Colon; Colorectal Neoplas

1989
Is neomycin necessary for bowel preparation in surgery of the colon? Oral neomycin plus erythromycin versus erythromycin-metronidazole.
    Canadian journal of surgery. Journal canadien de chirurgie, 1989, Volume: 32, Issue:4

    Topics: Administration, Oral; Aged; Bacteria, Anaerobic; Clinical Trials as Topic; Colon; Colorectal Neoplas

1989

Other Studies

11 other studies available for metronidazole and Colorectal Neoplasms

ArticleYear
Metronidazole Delivery Nanosystem Able To Reduce the Pathogenicity of Bacteria in Colorectal Infection.
    Biomacromolecules, 2022, 06-13, Volume: 23, Issue:6

    Topics: Anti-Bacterial Agents; Bacteria; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Escherichia

2022
Metronidazole Delivery Nanosystem Able To Reduce the Pathogenicity of Bacteria in Colorectal Infection.
    Biomacromolecules, 2022, 06-13, Volume: 23, Issue:6

    Topics: Anti-Bacterial Agents; Bacteria; Chitosan; Colorectal Neoplasms; Drug Delivery Systems; Escherichia

2022
Optimal timing for antimicrobial prophylaxis to reduce surgical site infections: a retrospective analysis of 531 patients.
    Scientific reports, 2023, 06-09, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cefuroxime; Colorectal Neoplas

2023
Optimal timing for antimicrobial prophylaxis to reduce surgical site infections: a retrospective analysis of 531 patients.
    Scientific reports, 2023, 06-09, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cefuroxime; Colorectal Neoplas

2023
Preoperative oral antibiotic administration in patients undergoing curative resection with stoma creation for colorectal cancer: effectiveness in preventing surgical site infection and the possibility of peristomal candidiasis induced by enterobacterial a
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2023, Volume: 25, Issue:11

    Topics: Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colorectal Neoplasms; Cross-Sec

2023
Preoperative oral antibiotic administration in patients undergoing curative resection with stoma creation for colorectal cancer: effectiveness in preventing surgical site infection and the possibility of peristomal candidiasis induced by enterobacterial a
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2023, Volume: 25, Issue:11

    Topics: Administration, Oral; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colorectal Neoplasms; Cross-Sec

2023
Effects of metronidazole on colorectal cancer occurrence and colorectal cancer liver metastases by regulating Fusobacterium nucleatum in mice.
    Immunity, inflammation and disease, 2023, Volume: 11, Issue:11

    Topics: Animals; Colorectal Neoplasms; DNA; Fusobacterium Infections; Fusobacterium nucleatum; Ki-67 Antigen

2023
Effects of metronidazole on colorectal cancer occurrence and colorectal cancer liver metastases by regulating Fusobacterium nucleatum in mice.
    Immunity, inflammation and disease, 2023, Volume: 11, Issue:11

    Topics: Animals; Colorectal Neoplasms; DNA; Fusobacterium Infections; Fusobacterium nucleatum; Ki-67 Antigen

2023
Erythrophagocytosis in colonic mucosa: real-time amazing display.
    BMJ case reports, 2020, Dec-12, Volume: 13, Issue:12

    Topics: Adult; Amebiasis; Antiprotozoal Agents; Colorectal Neoplasms; Gastrointestinal Hemorrhage; Humans; I

2020
Erythrophagocytosis in colonic mucosa: real-time amazing display.
    BMJ case reports, 2020, Dec-12, Volume: 13, Issue:12

    Topics: Adult; Amebiasis; Antiprotozoal Agents; Colorectal Neoplasms; Gastrointestinal Hemorrhage; Humans; I

2020
Analysis of
    Science (New York, N.Y.), 2017, 12-15, Volume: 358, Issue:6369

    Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Bacteroides; Carcinogenesis; Colorectal Neoplasms; F

2017
Analysis of
    Science (New York, N.Y.), 2017, 12-15, Volume: 358, Issue:6369

    Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Bacteroides; Carcinogenesis; Colorectal Neoplasms; F

2017
Metronidazole decreases viability of DLD-1 colorectal cancer cell line.
    Cancer biotherapy & radiopharmaceuticals, 2013, Volume: 28, Issue:8

    Topics: Anti-Infective Agents; Antineoplastic Agents; Cell Growth Processes; Cell Line, Tumor; Cell Survival

2013
Metronidazole decreases viability of DLD-1 colorectal cancer cell line.
    Cancer biotherapy & radiopharmaceuticals, 2013, Volume: 28, Issue:8

    Topics: Anti-Infective Agents; Antineoplastic Agents; Cell Growth Processes; Cell Line, Tumor; Cell Survival

2013
Interstitial laser hyperthermia for colorectal liver metastases: the effect of thermal sensitization and the use of a cylindrical diffuser tip on tumor necrosis.
    Journal of clinical laser medicine & surgery, 2002, Volume: 20, Issue:4

    Topics: Animals; Colorectal Neoplasms; Hyperthermia, Induced; Laser Therapy; Liver Neoplasms, Experimental;

2002
Interstitial laser hyperthermia for colorectal liver metastases: the effect of thermal sensitization and the use of a cylindrical diffuser tip on tumor necrosis.
    Journal of clinical laser medicine & surgery, 2002, Volume: 20, Issue:4

    Topics: Animals; Colorectal Neoplasms; Hyperthermia, Induced; Laser Therapy; Liver Neoplasms, Experimental;

2002
[Use of antibiotics in colorectal surgery in Denmark].
    Ugeskrift for laeger, 2007, Mar-05, Volume: 169, Issue:10

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cefuroxime; Colore

2007
[Use of antibiotics in colorectal surgery in Denmark].
    Ugeskrift for laeger, 2007, Mar-05, Volume: 169, Issue:10

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cefuroxime; Colore

2007
Nd-YAG laser therapy for palliation of obstructed colorectal carcinomas.
    Indian journal of cancer, 1994, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Fema

1994
Nd-YAG laser therapy for palliation of obstructed colorectal carcinomas.
    Indian journal of cancer, 1994, Volume: 31, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Fema

1994
1989 Henry Baker lecture. Inflammatory bowel disease: back to the future.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:4

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Awards and Prizes; Colorectal Neoplasms; Gastroentero

1990
1989 Henry Baker lecture. Inflammatory bowel disease: back to the future.
    The American journal of gastroenterology, 1990, Volume: 85, Issue:4

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Awards and Prizes; Colorectal Neoplasms; Gastroentero

1990