metronidazole has been researched along with Colonic Diverticulosis in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Arezzo, A | 1 |
| Nicotera, A | 1 |
| Bonomo, LD | 1 |
| Olandese, F | 1 |
| Veglia, S | 1 |
| Ferguglia, A | 1 |
| Pentassuglia, G | 1 |
| Mingrone, G | 1 |
| Morino, M | 1 |
| Cash, BD | 1 |
| Zamudio-Tiburcio, Á | 1 |
| Bermúdez-Ruiz, H | 1 |
| Lezama-Guzmán, HR | 1 |
| Guevara-Ortigoza, MDP | 1 |
| Islas-Solares, E | 1 |
| Sosa-López, FA | 1 |
| Tursi, A | 1 |
| Elisei, W | 1 |
| Brandimarte, G | 1 |
| Giorgetti, GM | 1 |
| Inchingolo, CD | 1 |
| Nenna, R | 1 |
| Picchio, M | 1 |
| Giorgio, F | 1 |
| Ierardi, E | 1 |
| Kolyvanos Naumann, U | 1 |
| Käser, L | 1 |
| Vetter, W | 1 |
| Raina, A | 1 |
| Kiss, L | 1 |
| Yadav, D | 1 |
1 review available for metronidazole and Colonic Diverticulosis
| Article | Year |
|---|---|
[Diverticulitis (acute)/diverticulosis of the colon].
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Diagnosis, Differential; | 2005 |
5 other studies available for metronidazole and Colonic Diverticulosis
| Article | Year |
|---|---|
Outcomes of surgical treatment of diverticular abscesses after failure of antibiotic therapy.
Topics: Abdominal Abscess; Abscess; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ci | 2023 |
Board Review Vignette: Segmental Colitis Associated With Diverticulosis.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Colitis; Colon, Sigmoid; Colonoscopy; Diverticulosis, Colonic; | 2016 |
[Breaking paradigms. Intestinal microbiota transplantation: Preliminar report].
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Celiac Disease; Colon; Comorbidity; Contraindications, Drug | 2017 |
Mucosal expression of basic fibroblastic growth factor, Syndecan 1 and tumor necrosis factor-alpha in diverticular disease of the colon: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Case | 2012 |
Electronic clinical challenges and images in GI. Ileal diverticulitis.
Topics: Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Digestive System Surgical Procedures; Diver | 2008 |