metronidazole has been researched along with Colitis, Mucous in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gastrointestinal complaints in patients with persistent or cleared giardiasis were unrelated to hydrogen breath excretion after lactulose challenge." | 3.74 | Lactulose breath test results in patients with persistent abdominal symptoms following Giardia lamblia infection. ( Berstad, A; Hausken, T; Morken, MH; Nysaeter, G; Strand, EA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Franklin, F | 1 |
| Rajamanikam, A | 1 |
| Raju, CS | 1 |
| Gill, JS | 1 |
| Francis, B | 1 |
| Sy-Cherng, LW | 1 |
| Kumar, S | 1 |
| Stollman, N | 1 |
| Smith, M | 1 |
| Giovanelli, A | 1 |
| Mendolia, G | 1 |
| Burns, L | 1 |
| Didyk, E | 1 |
| Burgess, J | 1 |
| Noh, A | 1 |
| Edelstein, C | 1 |
| Alm, E | 1 |
| Kassam, Z | 1 |
| Zamudio-Tiburcio, Á | 1 |
| Bermúdez-Ruiz, H | 1 |
| Lezama-Guzmán, HR | 1 |
| Guevara-Ortigoza, MDP | 1 |
| Islas-Solares, E | 1 |
| Sosa-López, FA | 1 |
| Madisch, A | 1 |
| Stensvold, CR | 2 |
| Lewis, HC | 1 |
| Hammerum, AM | 1 |
| Porsbo, LJ | 1 |
| Nielsen, SS | 1 |
| Olsen, KE | 1 |
| Arendrup, MC | 1 |
| Nielsen, HV | 2 |
| Mølbak, K | 1 |
| Engsbro, AL | 1 |
| Bytzer, P | 1 |
| Dear, KL | 1 |
| Elia, M | 1 |
| Hunter, JO | 1 |
| Morken, MH | 1 |
| Nysaeter, G | 1 |
| Strand, EA | 1 |
| Hausken, T | 1 |
| Berstad, A | 1 |
1 review available for metronidazole and Colitis, Mucous
| Article | Year |
|---|---|
[Diagnostics and therapy of chronic diarrhea in elderly people].
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents; Antidiarrheal | 2008 |
1 trial available for metronidazole and Colitis, Mucous
| Article | Year |
|---|---|
Do interventions which reduce colonic bacterial fermentation improve symptoms of irritable bowel syndrome?
Topics: Adult; Anti-Infective Agents; Bacteria; Breath Tests; Calorimetry; Circadian Rhythm; Colon; Colony C | 2005 |
6 other studies available for metronidazole and Colitis, Mucous
| Article | Year |
|---|---|
Higher amoebic and metronidazole resistant forms of Blastocystis sp. seen in schizophrenic patients.
Topics: Blastocystis; Blastocystis Infections; Feces; Humans; Irritable Bowel Syndrome; Metronidazole | 2022 |
Frozen encapsulated stool in recurrent Clostridium difficile: exploring the role of pills in the treatment hierarchy of fecal microbiota transplant nonresponders.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Biological Therapy; | 2015 |
[Breaking paradigms. Intestinal microbiota transplantation: Preliminar report].
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Celiac Disease; Colon; Comorbidity; Contraindications, Drug | 2017 |
Blastocystis: unravelling potential risk factors and clinical significance of a common but neglected parasite.
Topics: Adolescent; Adult; Aged; Animals; Antiparasitic Agents; Blastocystis; Blastocystis Infections; Child | 2009 |
Treatment of Dientamoeba fragilis in patients with irritable bowel syndrome.
Topics: Adult; Antiprotozoal Agents; Denmark; Dientamoeba; Dientamoebiasis; Feces; Female; Humans; Irritable | 2012 |
Lactulose breath test results in patients with persistent abdominal symptoms following Giardia lamblia infection.
Topics: Abdominal Pain; Adolescent; Adult; Animals; Antiprotozoal Agents; Breath Tests; Female; Giardia lamb | 2008 |