metronidazole has been researched along with Colitis, Ischemic in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Colitis, Ischemic: Inflammation of the COLON due to colonic ISCHEMIA resulting from alterations in systemic circulation or local vasculature.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the case of a 54-year-old woman with relapse of multiple myeloma 3 years after myeloablative allogeneic stem cell transplant who developed abdominal pain and bloody diarrhea following 7 months of lenalidomide therapy." | 7.83 | Ischemic colitis diagnosed by magnetic resonance imaging during lenalidomide treatment in a patient with relapsed multiple myeloma. ( Bucalossi, A; Cioffi Squitieri, N; Guerrini, S; Mazzei, FG; Mazzei, MA; Volterrani, L, 2016) |
| "We describe the case of a 54-year-old woman with relapse of multiple myeloma 3 years after myeloablative allogeneic stem cell transplant who developed abdominal pain and bloody diarrhea following 7 months of lenalidomide therapy." | 3.83 | Ischemic colitis diagnosed by magnetic resonance imaging during lenalidomide treatment in a patient with relapsed multiple myeloma. ( Bucalossi, A; Cioffi Squitieri, N; Guerrini, S; Mazzei, FG; Mazzei, MA; Volterrani, L, 2016) |
| "Here we present a case of fulminant amoebic colitis in a patient with SLE which was initially misdiagnosed as ischemic colitis due to intestinal vasculitis." | 1.38 | Fulminant amoebic colitis mimicking intestinal vasculitis in a patient with systemic lupus erythematosus. ( Ju, JH; Jung, HS; Kim, HY; Kwok, SK; Lee, J; Nam, HC; Park, KS; Park, SH, 2012) |
| "Ischemic colitis is a rare complication of HRT that should not be ignored when HRT is prescribed." | 1.35 | Ischemic colitis in postmenopausal women taking hormone replacement therapy. ( Calpaktsoglou, C; Diakakis, I; Grammatopoulos, T; Iatrakis, G; Katsoras, G; Tsionis, C; Zafiriou, S; Zervoudis, S, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, HS | 1 |
| Kim, HM | 1 |
| Gweon, TG | 1 |
| Guerrini, S | 1 |
| Bucalossi, A | 1 |
| Cioffi Squitieri, N | 1 |
| Mazzei, FG | 1 |
| Volterrani, L | 1 |
| Mazzei, MA | 1 |
| Zervoudis, S | 1 |
| Grammatopoulos, T | 1 |
| Iatrakis, G | 1 |
| Katsoras, G | 1 |
| Tsionis, C | 1 |
| Diakakis, I | 1 |
| Calpaktsoglou, C | 1 |
| Zafiriou, S | 1 |
| Lee, J | 1 |
| Jung, HS | 1 |
| Nam, HC | 1 |
| Kwok, SK | 1 |
| Ju, JH | 1 |
| Park, KS | 1 |
| Kim, HY | 1 |
| Park, SH | 1 |
4 other studies available for metronidazole and Colitis, Ischemic
| Article | Year |
|---|---|
Case of Pseudomembranous Colitis Caused by a
Topics: Anti-Bacterial Agents; Clostridium Infections; Colitis, Ischemic; Cytomegalovirus Infections; Diarrh | 2023 |
Ischemic colitis diagnosed by magnetic resonance imaging during lenalidomide treatment in a patient with relapsed multiple myeloma.
Topics: Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Colitis, Ischemic; Combined M | 2016 |
Ischemic colitis in postmenopausal women taking hormone replacement therapy.
Topics: Adult; Aged; Anti-Infective Agents; Colitis, Ischemic; Estrogen Replacement Therapy; Estrogens; Fema | 2008 |
Fulminant amoebic colitis mimicking intestinal vasculitis in a patient with systemic lupus erythematosus.
Topics: Antiprotozoal Agents; Colitis, Ischemic; Diagnosis, Differential; Diagnostic Errors; Dysentery, Ameb | 2012 |