metronidazole has been researched along with Co-infection in 18 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Less than 20% of patients with trichomoniasis were submitted to a complete screening for other genital pathogens." | 5.56 | Trichomoniasis in a tertiary hospital of Madrid, Spain (2013-2017): prevalence and pregnancy rate, coinfections, metronidazole resistance, and endosymbiosis. ( Bolumburu, C; Escario, JA; Ibáñez-Escribano, A; Muñoz-Algarra, M; Portero-Azorín, F; Zamora, V, 2020) |
| "The following keywords were used: bacterial vaginosis and treatment or management or therapy or prophylaxis or prevention." | 2.50 | Treatment of bacterial vaginosis: what we have and what we miss. ( Donders, GG; Rezeberga, D; Zodzika, J, 2014) |
| "Less than 20% of patients with trichomoniasis were submitted to a complete screening for other genital pathogens." | 1.56 | Trichomoniasis in a tertiary hospital of Madrid, Spain (2013-2017): prevalence and pregnancy rate, coinfections, metronidazole resistance, and endosymbiosis. ( Bolumburu, C; Escario, JA; Ibáñez-Escribano, A; Muñoz-Algarra, M; Portero-Azorín, F; Zamora, V, 2020) |
| "Metronidazole treatment failure was significantly more frequent in patients with E." | 1.43 | Is the treatment of Enterobius vermicularis co-infection necessary to eradicate Dientamoeba fragilis infection? ( Boga, JA; Fernández, J; Iglesias, C; Martínez-Camblor, P; Rodríguez, M; Rodríguez-Guardado, A; Rojo, S; Vázquez, F, 2016) |
| "Although polymicrobial infections, such as peri-implantitis or periodontitis, were postulated in the literature to be caused by synergistic effects of bacteria, these effects remain unclear looking at antibiotic susceptibility." | 1.37 | Antibiotic susceptibility of cocultures in polymicrobial infections such as peri-implantitis or periodontitis: an in vitro model. ( Al-Nawas, B; d'Hoedt, B; Karbach, J; Mouratidou, A, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 16 (88.89) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Sgibnev, A | 1 |
| Kremleva, E | 1 |
| Bolumburu, C | 1 |
| Zamora, V | 1 |
| Muñoz-Algarra, M | 1 |
| Portero-Azorín, F | 1 |
| Escario, JA | 1 |
| Ibáñez-Escribano, A | 1 |
| Sherley, M | 1 |
| Martin, SJ | 1 |
| Tambe, S | 1 |
| Zambare, U | 1 |
| Nayak, C | 1 |
| Graves, KJ | 1 |
| Ghosh, AP | 1 |
| Schmidt, N | 1 |
| Augostini, P | 1 |
| Secor, WE | 1 |
| Schwebke, JR | 1 |
| Martin, DH | 1 |
| Kissinger, PJ | 1 |
| Muzny, CA | 1 |
| Donders, GG | 1 |
| Zodzika, J | 1 |
| Rezeberga, D | 1 |
| Abdulrahman, GO | 1 |
| Gateley, CA | 1 |
| Hirt, RP | 1 |
| Sherrard, J | 1 |
| Falcone, M | 1 |
| Russo, A | 1 |
| Iraci, F | 1 |
| Carfagna, P | 1 |
| Goldoni, P | 1 |
| Vullo, V | 1 |
| Venditti, M | 1 |
| Bogdan, M | 1 |
| Zujić Atalić, V | 1 |
| Hećimović, I | 1 |
| Vuković, D | 1 |
| Boga, JA | 1 |
| Rojo, S | 1 |
| Fernández, J | 1 |
| Rodríguez, M | 1 |
| Iglesias, C | 1 |
| Martínez-Camblor, P | 1 |
| Vázquez, F | 1 |
| Rodríguez-Guardado, A | 1 |
| Hazarika, M | 1 |
| Pai H, V | 1 |
| Khanna, V | 1 |
| Reddy, H | 1 |
| Tilak, K | 1 |
| Chawla, K | 1 |
| Pérez-Chacón, G | 1 |
| Pocaterra, LA | 1 |
| Rojas, E | 1 |
| Hernán, A | 1 |
| Jiménez, JC | 1 |
| Núñez, L | 1 |
| Mouratidou, A | 1 |
| Karbach, J | 1 |
| d'Hoedt, B | 1 |
| Al-Nawas, B | 1 |
| Boyanova, L | 1 |
| Ilieva, J | 1 |
| Gergova, G | 1 |
| Davidkov, L | 1 |
| Spassova, Z | 1 |
| Kamburov, V | 1 |
| Katsarov, N | 1 |
| Mitov, I | 1 |
| Wang'ondu, RW | 1 |
| Murray, TS | 1 |
| Wang, PJ | 1 |
| Xie, CB | 1 |
| Coleman, JS | 1 |
| Gaydos, CA | 1 |
| Witter, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment Of Changes In Gut Microbiota Of Patients With Recurrent Clostridioides Difficile Infection After Fecal Microbiota Transplantation: Prospective Study[NCT05739825] | 20 participants (Anticipated) | Observational | 2023-02-13 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for metronidazole and Co-infection
| Article | Year |
|---|---|
Treatment of bacterial vaginosis: what we have and what we miss.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Clindamycin; Coinfection; Drug Therapy, Combina | 2014 |
Trichomonas vaginalis origins, molecular pathobiology and clinical considerations.
Topics: Antiprotozoal Agents; Bacterial Vaccines; Coinfection; DNA, Bacterial; DNA, Protozoan; Female; Host- | 2015 |
Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies.
Topics: Anti-Infective Agents; Coinfection; Directive Counseling; Female; HIV Infections; Humans; Metronidaz | 2013 |
1 trial available for metronidazole and Co-infection
| Article | Year |
|---|---|
Probiotics in addition to metronidazole for treatment Trichomonas vaginalis in the presence of BV: a randomized, placebo-controlled, double-blind study.
Topics: Administration, Intravaginal; Adult; Antiprotozoal Agents; Coinfection; Combined Modality Therapy; F | 2020 |
14 other studies available for metronidazole and Co-infection
| Article | Year |
|---|---|
Trichomoniasis in a tertiary hospital of Madrid, Spain (2013-2017): prevalence and pregnancy rate, coinfections, metronidazole resistance, and endosymbiosis.
Topics: Adult; Coinfection; Drug Resistance; Female; Gonorrhea; Humans; Metronidazole; Middle Aged; Mycoplas | 2020 |
Multiple simultaneous infections in a patient with well-controlled HIV: when Occam's razor fails.
Topics: Acquired Immunodeficiency Syndrome; Aftercare; AIDS-Related Opportunistic Infections; Anti-Retrovira | 2017 |
Nodulo-ulcerative and erythrodermic secondary syphilis in human immunodeficiency virus-infected individuals.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Chancre; | 2019 |
Trichomonas vaginalis Virus Among Women With Trichomoniasis and Associations With Demographics, Clinical Outcomes, and Metronidazole Resistance.
Topics: Adult; Coinfection; Drug Resistance; Female; Humans; Metronidazole; Middle Aged; Parasitic Sensitivi | 2019 |
Primary actinomycosis of the breast caused by Actinomyces turicensis with associated Peptoniphilus harei.
Topics: Actinomyces; Actinomycosis; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Breast Diseas | 2015 |
Risk Factors and Outcomes for Bloodstream Infections Secondary to Clostridium difficile Infection.
Topics: Aged; Anti-Infective Agents; Bacteremia; Candida; Candidiasis; Case-Control Studies; Clostridioides | 2016 |
Brain abscess due to Aggregatibacter aphrophilus and Bacteroides uniformis.
Topics: Adolescent; Aggregatibacter aphrophilus; Anti-Bacterial Agents; Bacteroides; Bacteroides Infections; | 2015 |
Is the treatment of Enterobius vermicularis co-infection necessary to eradicate Dientamoeba fragilis infection?
Topics: Adolescent; Adult; Aged; Animals; Anthelmintics; Antiprotozoal Agents; Child; Child, Preschool; Coin | 2016 |
Rare Case of Polymicrobial Keratitis With Balantidium coli.
Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Balantidiasis; Balantidium; Coinfection; Contact Lenses | 2016 |
Coinfection with
Topics: Adult; Animals; Anthelmintics; Anti-HIV Agents; Antiprotozoal Agents; Coinfection; Diarrhea; Giardia | 2017 |
Antibiotic susceptibility of cocultures in polymicrobial infections such as peri-implantitis or periodontitis: an in vitro model.
Topics: Acetamides; Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Amoxicillin; Amoxicill | 2011 |
Numerous risk factors for Helicobacter pylori antibiotic resistance revealed by extended anamnesis: a Bulgarian study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bulgaria; Clarithromycin; Coinfec | 2012 |
Relapse of polymicrobial endocarditis in an intravenous drug user.
Topics: Adult; Ceftriaxone; Coinfection; Eikenella corrodens; Endocarditis, Bacterial; Gram-Negative Bacteri | 2011 |
[Mycoplasma hominis symbiosis and Trichomonas vaginalis metronidazole resistance].
Topics: Coinfection; Female; Humans; Metronidazole; Mycoplasma hominis; Mycoplasma Infections; Trichomonas I | 2012 |