metronidazole has been researched along with Circulatory Collapse in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of the cases was diagnosed as food poisoning, a second as a case of hypovolemic shock and the third also as a hypovolemic shock, though also considered to have sepsis and the last, a case of acute exacerbation of asthmatic attack." | 1.36 | Unusual presentations of Giardia lamblia; a report of four cases. ( Igbodo, C; Obidike, EO, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Obidike, EO | 1 |
| Igbodo, C | 1 |
| Steudel, HC | 1 |
| Gugler, R | 1 |
| Sun, XM | 1 |
| MacKendrick, W | 1 |
| Tien, J | 1 |
| Huang, W | 1 |
| Caplan, MS | 1 |
| Hsueh, W | 1 |
3 other studies available for metronidazole and Circulatory Collapse
| Article | Year |
|---|---|
Unusual presentations of Giardia lamblia; a report of four cases.
Topics: Animals; Antiprotozoal Agents; Child; Diagnosis, Differential; Feces; Female; Foodborne Diseases; Gi | 2010 |
[Postpartum pseudomembranous colitis].
Topics: Adult; Cefotaxime; Colon; Colonoscopy; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; F | 1984 |
Endogenous bacterial toxins are required for the injurious action of platelet-activating factor in rats.
Topics: Analysis of Variance; Animals; Bacterial Toxins; Drug Therapy, Combination; Endotoxins; Intestines; | 1995 |