metronidazole has been researched along with Cholera in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cholera: An acute diarrheal disease endemic in India and Southeast Asia whose causative agent is VIBRIO CHOLERAE. This condition can lead to severe dehydration in a matter of hours unless quickly treated.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
van Zwetselaar, M | 1 |
Nyombi, B | 1 |
Sonda, T | 1 |
Kumburu, H | 1 |
Chamba, N | 1 |
Dekker, MCJ | 1 |
Kilonzo, KG | 1 |
Urasa, SJ | 1 |
Mmbaga, BT | 1 |
Woodruff, AW | 1 |
2 other studies available for metronidazole and Cholera
Article | Year |
---|---|
Aeromonas caviae mimicking Vibrio cholerae infectious enteropathy in a cholera-endemic region with possible public health consequences: two case reports.
Topics: Acetaminophen; Adult; Aeromonas caviae; Anti-Bacterial Agents; Cholera; Ciprofloxacin; Diagnosis, Di | 2018 |
Current practice in tropical medicine.
Topics: Acute Kidney Injury; Amebiasis; Amebicides; Chloroquine; Cholera; Drug Resistance, Microbial; Hepati | 1969 |