metronidazole has been researched along with Cholelithiasis in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cholelithiasis: Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Emphysematous gastritis is a life-threatening disease." | 2.42 | Emphysematous gastritis and severe aplastic anemia. ( Cantalapiedra, A; Del Villar, R; García-Frade, LJ; Gutierrez, O; Peñarrubia, MJ; Sales, R; Tabuyo, MI, 2003) |
| "The incidence of bacterial infection are higher in the pigmented calcium stone than cholesterol stone." | 1.28 | [Anaerobes in biliary tract infection]. ( Fu, HQ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Pašić, F | 1 |
| Delibegović, S | 1 |
| Gutierrez, O | 1 |
| Cantalapiedra, A | 1 |
| Tabuyo, MI | 1 |
| Del Villar, R | 1 |
| Peñarrubia, MJ | 1 |
| Sales, R | 1 |
| García-Frade, LJ | 1 |
| Kocherovets, VI | 1 |
| Stolbovoĭ, AV | 1 |
| Dzhalashev, IaKh | 1 |
| Cohen, SE | 1 |
| Ligumsky, M | 1 |
| Bar-Ziv, J | 1 |
| Safadi, R | 1 |
| Low-Beer, TS | 1 |
| Nutter, S | 1 |
| Sridharan, GV | 1 |
| Wilkinson, SP | 1 |
| Primrose, WR | 1 |
| Fu, HQ | 1 |
2 reviews available for metronidazole and Cholelithiasis
| Article | Year |
|---|---|
Emphysematous gastritis and severe aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cholelithiasis; Cyclosporine; Emphysema; Female; Gastritis; | 2003 |
[Non-clostridial anaerobic infection in diseases of the liver and biliary tract (review of the Soviet and foreign literature)].
Topics: Age Factors; Aged; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Biliary Tract D | 1984 |
5 other studies available for metronidazole and Cholelithiasis
| Article | Year |
|---|---|
THE USE OF MICROBIOLOGICAL AND LABORATORY DATA IN THE CHOICE OF EMPIRICAL ANTIBIOTIC THERAPY IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY - THE ROLE OF LOCAL ANTIBIOGRAMS.
Topics: Anti-Bacterial Agents; Cefazolin; Cholecystectomy, Laparoscopic; Cholecystitis, Acute; Cholelithiasi | 2022 |
Conservative therapy in an ERCP-induced abdominal abscess.
Topics: Abdominal Abscess; Adult; Ampicillin; Aztreonam; Cholangiopancreatography, Endoscopic Retrograde; Ch | 1996 |
Colonic bacterial activity, biliary cholesterol saturation, and pathogenesis of gallstones.
Topics: Adult; Anticholesteremic Agents; Bacteroides; Bile; Cholelithiasis; Cholesterol; Colon; Deoxycholic | 1978 |
Pyogenic liver abscess in the elderly.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cholelithiasis; Diagnosis, Differential; Diverticuli | 1990 |
[Anaerobes in biliary tract infection].
Topics: Adolescent; Adult; Aged; Bacteria, Anaerobic; Bacterial Infections; Bile; Biliary Tract Neoplasms; C | 1989 |