metronidazole has been researched along with Cholecystitis, Acute in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cholecystitis, Acute: Acute inflammation of the GALLBLADDER wall. It is characterized by the presence of ABDOMINAL PAIN; FEVER; and LEUKOCYTOSIS. Gallstone obstruction of the CYSTIC DUCT is present in approximately 90% of the cases.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Pašić, F | 1 |
| Delibegović, S | 1 |
| Bari, H | 1 |
| Khan, MR | 1 |
| Shariff, AH | 1 |
| Füessl, HS | 1 |
| Yanni, F | 1 |
| Mekhail, P | 1 |
| Morris-Stiff, G | 1 |
| Loozen, CS | 1 |
| Kortram, K | 1 |
| Kornmann, VN | 1 |
| van Ramshorst, B | 1 |
| Vlaminckx, B | 1 |
| Knibbe, CA | 1 |
| Kelder, JC | 1 |
| Donkervoort, SC | 1 |
| Nieuwenhuijzen, GA | 1 |
| Ponten, JE | 1 |
| van Geloven, AA | 1 |
| van Duijvendijk, P | 1 |
| Bos, WJ | 1 |
| Besselink, MG | 1 |
| Gouma, DJ | 1 |
| van Santvoort, HC | 1 |
| Boerma, D | 1 |
| Hefny, AF | 1 |
| Torab, FC | 1 |
| Joshi, S | 1 |
| Sebastian, M | 1 |
| Abu-Zidan, FM | 1 |
1 review available for metronidazole and Cholecystitis, Acute
| Article | Year |
|---|---|
Actinomycosis of the gallbladder: case report and review of the literature.
Topics: Actinomycosis; Anti-Bacterial Agents; Cholecystectomy, Laparoscopic; Cholecystitis, Acute; Diagnosis | 2005 |
1 trial available for metronidazole and Cholecystitis, Acute
| Article | Year |
|---|---|
Randomized clinical trial of extended versus single-dose perioperative antibiotic prophylaxis for acute calculous cholecystitis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Cefazolin; Cefuroxime | 2017 |
4 other studies available for metronidazole and Cholecystitis, Acute
| Article | Year |
|---|---|
THE USE OF MICROBIOLOGICAL AND LABORATORY DATA IN THE CHOICE OF EMPIRICAL ANTIBIOTIC THERAPY IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY - THE ROLE OF LOCAL ANTIBIOGRAMS.
Topics: Anti-Bacterial Agents; Cefazolin; Cholecystectomy, Laparoscopic; Cholecystitis, Acute; Cholelithiasi | 2022 |
Antibiotics in acute calculous cholecystitis - do Tokyo guidelines influence the surgeons' practices?
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Cefazolin; Ceftriaxone; Cholecystectomy; Cholecystectomy, | 2017 |
[Acute cholecystitis].
Topics: Adult; Amoxicillin; Analgesics, Opioid; Anti-Bacterial Agents; Butylscopolammonium Bromide; Cholecys | 2013 |
A selective antibiotic prophylaxis policy for laparoscopic cholecystectomy is effective in minimising infective complications.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cephalosporins; Cholecystectomy, Laparoscopic; Cholec | 2013 |