metronidazole has been researched along with Cervix Diseases in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stöckli, A | 1 |
| Wernekinck, C | 1 |
| Dahmane, N | 1 |
| Persson, A | 1 |
| Thomassen, P | 1 |
| Willmott, FE | 1 |
| White, DJ | 1 |
| Malet, R | 1 |
| Ahmed-Jushuf, IH | 1 |
| Woodcock, K | 1 |
| McClatchie, S | 1 |
| Sambhi, JS | 1 |
| Tóth, B | 1 |
| Simon, J | 1 |
| Zawadzki, J | 1 |
| Starzyk, J | 1 |
1 trial available for metronidazole and Cervix Diseases
| Article | Year |
|---|---|
Antibiotic prophylaxis for cold coagulation of the cervix?
Topics: Cryosurgery; Female; Humans; Metronidazole; Postoperative Complications; Sulfonamides; Uterine Cervi | 1992 |
7 other studies available for metronidazole and Cervix Diseases
| Article | Year |
|---|---|
[New therapeutic and diagnostic points of view in gynecology].
Topics: Female; Genital Diseases, Female; Humans; Metronidazole; Pregnancy; Trichomonas Vaginitis; Urinary I | 1967 |
Ovarian vein thrombosis with symptoms prior to term--a case report.
Topics: Adult; Anticoagulants; Bacteroides; Bacteroides Infections; C-Reactive Protein; Diagnosis, Different | 1997 |
Genital yeasts in female patients attending a VD clinic.
Topics: Adolescent; Adult; Age Factors; Anti-Bacterial Agents; Candida albicans; Candidiasis, Vulvovaginal; | 1975 |
Antibiotic prophylaxis for cold coagulation of the cervix.
Topics: Cervix Uteri; Electrocoagulation; Female; Humans; Metronidazole; Premedication; Uterine Cervical Dis | 1992 |
Amoebiasis of the cervix uteri.
Topics: Amebiasis; Biopsy; Diagnosis, Differential; Emetine; Entamoeba histolytica; Female; Humans; Malaysia | 1971 |
[The role of urogenital trichomonas in the genesis of changes in the portio epithelium].
Topics: Antifungal Agents; Antiprotozoal Agents; Antitrichomonal Agents; Cervix Uteri; Epithelium; Female; H | 1969 |
[Significance of the treatment of trichomoniasis in gynecology and obstetrics].
Topics: Abortion, Spontaneous; Antiprotozoal Agents; Antitrichomonal Agents; Appendicitis; Female; Humans; M | 1969 |