metronidazole has been researched along with Cervicitis in 18 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The data on paraendocervical administration of metronidazole in the treatment of patients with relapsing Trichomonas endocervicitis are presented." | 7.72 | [Paraendocervical route for metronidazole administration in complex treatment of chronic Trichomonas endocervicitis]. ( Borisova, LV; Churakov, AA; Kulichenko, AN; Malykhina, ZV; Skatin, AV; Suvorov, AP, 2004) |
| "Women with clinically diagnosed cervicitis and BV received doxycycline and ofloxacin and were randomized to treatment with metronidazole gel or placebo." | 5.10 | Interrelationships of bacterial vaginosis and cervical inflammation. ( Schwebke, JR; Weiss, HL, 2002) |
| "The data on paraendocervical administration of metronidazole in the treatment of patients with relapsing Trichomonas endocervicitis are presented." | 3.72 | [Paraendocervical route for metronidazole administration in complex treatment of chronic Trichomonas endocervicitis]. ( Borisova, LV; Churakov, AA; Kulichenko, AN; Malykhina, ZV; Skatin, AV; Suvorov, AP, 2004) |
| "To study the clinical manifestation and treatment of bacterial vaginosis (BV)." | 1.29 | [Clinical analysis of bacterial vaginosis in 76 cases]. ( Song, X; Weng, L; Yu, X, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (61.11) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woods, JL | 1 |
| Scurlock, AM | 1 |
| Hensel, DJ | 1 |
| McCormick, DF | 1 |
| Rahman, M | 1 |
| Zadrozny, S | 1 |
| Alam, A | 1 |
| Ashraf, L | 1 |
| Neilsen, GA | 1 |
| Kelly, R | 1 |
| Menezes, P | 1 |
| Miller, WC | 1 |
| Hoffman, IF | 1 |
| PHILIPP, EE | 1 |
| Churakov, AA | 1 |
| Skatin, AV | 1 |
| Borisova, LV | 1 |
| Malykhina, ZV | 1 |
| Kulichenko, AN | 1 |
| Suvorov, AP | 1 |
| Gray, B | 1 |
| Harper, WF | 1 |
| Still, RM | 1 |
| Stöckli, A | 1 |
| Smith, LS | 1 |
| Lauver, D | 1 |
| Fleury, FJ | 1 |
| Yu, X | 1 |
| Weng, L | 1 |
| Song, X | 1 |
| Chandeying, V | 1 |
| Skov, S | 1 |
| Kemapunmanus, M | 1 |
| Law, M | 1 |
| Geater, A | 1 |
| Rowe, P | 1 |
| Lanta, S | 1 |
| Mention, JE | 1 |
| Schwebke, JR | 1 |
| Weiss, HL | 1 |
| Berg, AO | 1 |
| Soman, MP | 1 |
| Heinz, KP | 1 |
| Grase, EU | 1 |
| Aure, JC | 2 |
| Gjonnaess, H | 2 |
| Walker, AH | 1 |
1 review available for metronidazole and Cervicitis
| Article | Year |
|---|---|
Lower genitourinary infections in women.
Topics: Amoxicillin; Anti-Infective Agents, Urinary; Cystitis; Diagnosis, Differential; Drug Combinations; F | 1986 |
3 trials available for metronidazole and Cervicitis
| Article | Year |
|---|---|
Prevention and control of sexually transmissible infections among hotel-based female sex workers in Dhaka, Bangladesh.
Topics: Adolescent; Anti-Bacterial Agents; Azithromycin; Bangladesh; Candidiasis, Vulvovaginal; Cefixime; Ch | 2013 |
Evaluation of two clinical protocols for the management of women with vaginal discharge in southern Thailand.
Topics: Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Clinical Protocols; Doxycycline; Female; Go | 1998 |
Interrelationships of bacterial vaginosis and cervical inflammation.
Topics: Administration, Oral; Administration, Topical; Adult; Anti-Bacterial Agents; Anti-Infective Agents; | 2002 |
14 other studies available for metronidazole and Cervicitis
| Article | Year |
|---|---|
Pelvic inflammatory disease in the adolescent: understanding diagnosis and treatment as a health care provider.
Topics: Adolescent; Anti-Bacterial Agents; Arkansas; Ceftriaxone; Centers for Disease Control and Prevention | 2013 |
VULVO-VAGINITIS.
Topics: Adolescent; Candidiasis, Vulvovaginal; Child; Diabetes Mellitus; Drug Therapy; Female; Gonorrhea; Hu | 1965 |
[Paraendocervical route for metronidazole administration in complex treatment of chronic Trichomonas endocervicitis].
Topics: Administration, Intravaginal; Adult; Animals; Antitrichomonal Agents; Female; Humans; Metronidazole; | 2004 |
The effect of metronidazole therapy on cervical histology in trichomoniasis.
Topics: Edema; Epithelium; Female; Hemorrhage; Humans; Hyperplasia; Leukocytes; Metronidazole; Trichomonas V | 1967 |
[New therapeutic and diagnostic points of view in gynecology].
Topics: Female; Genital Diseases, Female; Humans; Metronidazole; Pregnancy; Trichomonas Vaginitis; Urinary I | 1967 |
Assessment and management of vaginitis and cervicitis.
Topics: Anti-Bacterial Agents; Antifungal Agents; Candidiasis, Vulvovaginal; Chlamydia Infections; Chlamydia | 1984 |
Adult vaginitis.
Topics: Atrophy; Female; Haemophilus Infections; Humans; Metronidazole; Trichomonas Vaginitis; Uterine Cervi | 1981 |
[Clinical analysis of bacterial vaginosis in 76 cases].
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteroidaceae Infections; Drugs, Chinese Herbal; Female; Humans | 1996 |
[Leukorrhea: diagnostic trends].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitricho | 1999 |
Amoebic infection of the female genital tract. A report of three cases.
Topics: Adult; Amebiasis; Carcinoma, Squamous Cell; Entamoeba histolytica; Female; Humans; Metronidazole; Mi | 1973 |
[Abnormal bleeding in trichomonas vaginalis].
Topics: Adolescent; Adult; Age Factors; Estradiol; Estrogens; Female; Humans; Menstruation Disturbances; Met | 1973 |
Metronidazole treatment of trichomonal vaginitis. A comparison of cure rates in 1961 and 1967.
Topics: Adolescent; Adult; Drug Resistance, Microbial; Female; Humans; Metronidazole; Middle Aged; Trichomon | 1969 |
Treatment of trichomonas vaginits with nifuratel.
Topics: Adolescent; Adult; Antiprotozoal Agents; Antitrichomonal Agents; Female; Humans; Metronidazole; Midd | 1969 |
Urinary symptoms caused by gynaecological lesions.
Topics: Adult; Estrogens; Female; Humans; Metronidazole; Middle Aged; Nystatin; Urination Disorders; Uterine | 1970 |