metronidazole has been researched along with Cerebromeningitis in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Brain abscess is a rare but life-threatening complication of pregnancy." | 1.37 | Pregnancy complicated by recurrent brain abscess after extraction of an infected tooth. ( Awonuga, AO; Hobson, DTG; Imudia, AN; Soto, E, 2011) |
| "Amphotericin B was highly amoebicidal in vitro and protected mice from infection with the organism." | 1.25 | Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis. ( Carter, RF, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Desai, A | 1 |
| Krishnan, A | 1 |
| Zaghloul, A | 1 |
| McClure, M | 1 |
| Hobson, DTG | 1 |
| Imudia, AN | 1 |
| Soto, E | 1 |
| Awonuga, AO | 1 |
| Hussain, MM | 1 |
| Mohan Rao, VK | 1 |
| Malhotra, KK | 1 |
| Kakar, PN | 1 |
| Pillay, P | 1 |
| Pathak, LR | 1 |
| Chuttani, HK | 1 |
| Singh, BN | 1 |
| Das, SR | 1 |
| Markowitz, SM | 1 |
| Martinez, AJ | 1 |
| Duma, RJ | 2 |
| Shiel, FO | 1 |
| Ferrell, HW | 1 |
| Nelson, EC | 1 |
| Jones, MM | 1 |
| De Carneri, I | 1 |
| Carter, RF | 1 |
10 other studies available for metronidazole and Cerebromeningitis
| Article | Year |
|---|---|
Calvarial osteomyelitis and intracranial extension post-Mohs micrographic surgery.
Topics: Aged; Anti-Bacterial Agents; Carcinoma, Basal Cell; Diagnosis, Differential; Female; Humans; Magneti | 2018 |
Pregnancy complicated by recurrent brain abscess after extraction of an infected tooth.
Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Brain Abscess; Cefotaxime; Cesarean Section; Dexameth | 2011 |
Effect of experimental meningoencephalitis on the aminotransferase levels in mouse brain.
Topics: Alanine Transaminase; Amebiasis; Amodiaquine; Animals; Aspartate Aminotransferases; Brain; Chlorhexi | 1979 |
Unusual presentation of primary amoebic meningoencephalitis--a serious diagnostic and therapeutic problem.
Topics: Adult; Amebiasis; Chloramphenicol; Drug Therapy, Combination; Female; Humans; Isoniazid; Meningoence | 1978 |
Studies on pathogenic and non-pathogenic small free-living amoebae and the bearing of nuclear division on the classification of the order amoebida.
Topics: Amebiasis; Amoeba; Animals; Antiprotozoal Agents; Biological Evolution; Brain; Cell Division; Cell N | 1970 |
Myocarditis associated with primary amebic (Naegleria) meningoencephalitis.
Topics: Adolescent; Adult; Amoeba; Amphotericin B; Brain; Bronchopneumonia; Child; Chloroquine; Electrocardi | 1974 |
Metronidazole (Flagyl) for amebiasis.
Topics: Amebiasis; Dysentery, Amebic; Humans; Liver Abscess, Amebic; Meningoencephalitis; Metronidazole; Rec | 1972 |
Primary amebic meningoencephalitis.
Topics: Adolescent; Amebiasis; Amoeba; Autopsy; Brain; Cerebrospinal Fluid; Chloroquine; Diagnosis, Differen | 1969 |
[1st results on the drugs active in vitro on soil amoebas which cause human meningoencephalitis].
Topics: Amoeba; Anti-Infective Agents; Arsenicals; Culture Media; Erythromycin; Humans; Meningoencephalitis; | 1970 |
Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis.
Topics: Amebiasis; Amoeba; Amphotericin B; Animals; Chloramphenicol; Emetine; Humans; Meningoencephalitis; M | 1969 |