metronidazole has been researched along with Cerebral Nocardiosis in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nocardia brain abscess is a rare condition, seen most commonly among immunocompromised patients." | 1.33 | A case of isolated Nocardia asteroides brain abscess in a kidney transplant recipient. ( Alişir, S; Cağatay, A; Görçin, S; Güven, D; Oztürk, S; Tufan, F; Türkmen, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oztürk, S | 1 |
| Tufan, F | 1 |
| Alişir, S | 1 |
| Görçin, S | 1 |
| Güven, D | 1 |
| Cağatay, A | 1 |
| Türkmen, A | 1 |
| Khan, SH | 1 |
| Sanche, SE | 1 |
| Robinson, CA | 1 |
| Pirouzmand, F | 1 |
2 other studies available for metronidazole and Cerebral Nocardiosis
| Article | Year |
|---|---|
A case of isolated Nocardia asteroides brain abscess in a kidney transplant recipient.
Topics: Adult; Antifungal Agents; Brain Abscess; Female; Humans; Immunosuppressive Agents; Kidney Failure, C | 2006 |
N. paucivorans infection presenting as a brain abscess.
Topics: Anti-Bacterial Agents; Brain Abscess; Brain Neoplasms; Diagnosis, Differential; Humans; Hypertension | 2006 |