metronidazole has been researched along with Celiac Sprue in 11 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treated with metronidazole, 500 mg twice daily for 6 days the patient reduced diarrhea after few days." | 1.48 | Improving basic skills in celiac-like disease diagnosis: a case report. ( Annibale, B; Antonelli, G; Coluccio, C; Corleto, VD; Di Cerbo, A; Di Marino, VP; Galli, G; Uccini, S, 2018) |
| "Although giardiasis is rare, its histopathological and serological picture may resemble that of CD." | 1.38 | Celiac disease and giardiasis: a case report. ( Bohr, J; Edling, L; Eriksson, S; Rathsman, S, 2012) |
| "Giardiasis is still regularly encountered in the United States, both as endemic cases from the local community as well as in patients returning from travel abroad." | 1.25 | Giardiasis in childhood. ( Burke, JA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mohammed, AD | 1 |
| Khan, MAW | 1 |
| Chatzistamou, I | 1 |
| Chamseddine, D | 1 |
| Williams-Kang, K | 1 |
| Perry, M | 1 |
| Enos, R | 1 |
| Murphy, A | 1 |
| Gomez, G | 1 |
| Aladhami, A | 1 |
| Oskeritzian, CA | 1 |
| Jolly, A | 1 |
| Chang, Y | 1 |
| He, S | 1 |
| Pan, Z | 1 |
| Kubinak, JL | 1 |
| Cerezo Lajas, A | 1 |
| Caminero Luna, JA | 1 |
| Rodríguez Guzmán, MDC | 1 |
| de Miguel Díez, J | 1 |
| Corleto, VD | 1 |
| Di Marino, VP | 1 |
| Galli, G | 1 |
| Antonelli, G | 1 |
| Coluccio, C | 1 |
| Di Cerbo, A | 1 |
| Uccini, S | 1 |
| Annibale, B | 1 |
| Majid, Z | 1 |
| Khalid, MA | 1 |
| Khan, SA | 1 |
| Achakzai, IK | 1 |
| Soomro, GB | 1 |
| Luck, NH | 1 |
| Nielsen, JA | 1 |
| Weber, JJ | 1 |
| Lager, DJ | 1 |
| Zamudio-Tiburcio, Á | 1 |
| Bermúdez-Ruiz, H | 1 |
| Lezama-Guzmán, HR | 1 |
| Guevara-Ortigoza, MDP | 1 |
| Islas-Solares, E | 1 |
| Sosa-López, FA | 1 |
| Edling, L | 1 |
| Rathsman, S | 1 |
| Eriksson, S | 1 |
| Bohr, J | 1 |
| Burke, JA | 1 |
| Ament, ME | 2 |
| Rubin, CE | 1 |
11 other studies available for metronidazole and Celiac Sprue
| Article | Year |
|---|---|
Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Bacterial; Antigens, CD19; B-Lymphocytes; Ce | 2019 |
Antituberculosis Treatment in a Patient with Celiac Disease.
Topics: Aged; Antitubercular Agents; Celiac Disease; Diarrhea; Diet, Gluten-Free; Drug Compounding; Drug Sub | 2018 |
Improving basic skills in celiac-like disease diagnosis: a case report.
Topics: Adult; Antiprotozoal Agents; Atrophy; Celiac Disease; Diagnosis, Differential; Duodenum; Female; Gia | 2018 |
Intestinal Spirocheteosis in a Patient with Celiac Disease.
Topics: Adolescent; Biopsy, Needle; Celiac Disease; Chronic Disease; Diarrhea; Diet, Gluten-Free; Endoscopy, | 2019 |
Diarrhoea and duodenal disease.
Topics: Adult; Antiprotozoal Agents; Celiac Disease; Colon; Duodenum; Giardiasis; Humans; Ileum; Male; Metro | 2014 |
[Breaking paradigms. Intestinal microbiota transplantation: Preliminar report].
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Celiac Disease; Colon; Comorbidity; Contraindications, Drug | 2017 |
Celiac disease and giardiasis: a case report.
Topics: Adult; Antibodies, Anti-Idiotypic; Biopsy; Celiac Disease; Diabetes Mellitus, Type 1; Diagnosis, Dif | 2012 |
Giardiasis in childhood.
Topics: Celiac Disease; Child; Child, Preschool; Diagnosis, Differential; Duodenum; Feces; Female; Giardiasi | 1975 |
Giardia lamblia and coeliac disease.
Topics: Age Factors; Biopsy; Celiac Disease; Child; Feces; Giardia; Giardiasis; Humans; Intestinal Mucosa; I | 1973 |
Relation of giardiasis to abnormal intestinal structure and function in gastrointestinal immunodeficiency syndromes.
Topics: Adult; Agammaglobulinemia; Celiac Disease; Duodenum; Female; Gastrointestinal Diseases; Giardiasis; | 1972 |
Diagnosis and treatment of giardiasis.
Topics: Adolescent; Biopsy; Celiac Disease; Child, Preschool; Diarrhea; Feces; Female; Giardia; Giardiasis; | 1972 |