metronidazole has been researched along with Cecal Diseases in 13 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cecal Diseases: Pathological developments in the CECUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of amidines and sulfonamides of 5- and 6-amino-2,3-bis(4-alkyl-1-piperazinyl)quinoxalines was synthesized and tested against cecal and hepatic forms of Entamoeba histolytica infections in rats and hamsters, respectively." | 3.66 | Antiamebic amidines and sulfonamides of 5- and 6-amino-2,3-bis(4-alkyl-1-piperazinyl)quinoxalines. ( Fabio, PF; Lang, SA; Lin, YI; Tomcufcik, AS, 1980) |
| "Amoeboma is a rare manifestation of intestinal amoebiasis." | 1.40 | Amoeboma: resurfacing of a vanishing illness. ( Alexander, T; Balasubramanian, P; Boopathy, V; Phansalkar, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fabio, PF | 1 |
| Lang, SA | 1 |
| Lin, YI | 1 |
| Tomcufcik, AS | 1 |
| Boopathy, V | 1 |
| Alexander, T | 1 |
| Balasubramanian, P | 1 |
| Phansalkar, M | 1 |
| Joshi, D | 1 |
| Aga, R | 1 |
| Koren, R | 1 |
| Dekel, Y | 1 |
| Ramadan, E | 1 |
| Veltman, V | 1 |
| Dreznik, Z | 1 |
| Matsuura, M | 1 |
| Nakase, H | 1 |
| Fujimori, T | 1 |
| Mizuma, K | 1 |
| Tsuda, Y | 1 |
| Chiba, T | 1 |
| Ray, DK | 2 |
| Shrivastava, VB | 2 |
| Tendulkar, JS | 2 |
| Dutta, AK | 1 |
| Bhopale, KK | 2 |
| Chatterjee, DK | 1 |
| Nagarajan, K | 2 |
| Russell, RJ | 1 |
| Haines, DC | 1 |
| Anver, MR | 1 |
| Battles, JK | 1 |
| Gorelick, PL | 1 |
| Blumenauer, LL | 1 |
| Gonda, MA | 1 |
| Ward, JM | 1 |
| Pradhan, KS | 1 |
| Masani, KB | 1 |
| Kaul, CL | 1 |
| Haff, RC | 1 |
| Norgaard, RP | 1 |
| Shapero, M | 1 |
| Jefferies, HS | 1 |
| Ryan, DM | 1 |
| Pittman, FE | 1 |
| Pittman, JC | 1 |
| el-Hashimi, WK | 1 |
| Balikian, JP | 1 |
| Uthman, SM | 1 |
| Khouri, NF | 1 |
13 other studies available for metronidazole and Cecal Diseases
| Article | Year |
|---|---|
Antiamebic amidines and sulfonamides of 5- and 6-amino-2,3-bis(4-alkyl-1-piperazinyl)quinoxalines.
Topics: Amebicides; Animals; Cecal Diseases; Cricetinae; Dysentery, Amebic; Entamoebiasis; Female; Liver Abs | 1980 |
Amoeboma: resurfacing of a vanishing illness.
Topics: Abdominal Pain; Antiprotozoal Agents; Cecal Diseases; Colonic Diseases; Dysentery, Amebic; Entamoeba | 2014 |
Cecal ameboma.
Topics: Amebiasis; Antiprotozoal Agents; Cecal Diseases; Cecum; Colonoscopy; Furans; Histocytochemistry; Hum | 2010 |
Periappendiceal actinomycosis mimicking malignancy report of a case.
Topics: Abscess; Actinomyces; Actinomycosis; Aged; Aged, 80 and over; Anti-Bacterial Agents; Appendectomy; A | 2002 |
Cecal ameboma.
Topics: Abdominal Pain; Amebiasis; Animals; Biopsy, Needle; Cecal Diseases; Colonoscopy; Follow-Up Studies; | 2005 |
Comparative studies on the amoebicidal activity of known 5-nitroimidazole derivatives and CG 10213-Go in golden hamsters, Mesocricetus auratus, infected in the liver or caecum or both with trophozoites of Entamoeba histolytica.
Topics: Amebicides; Animals; Cecal Diseases; Cricetinae; Dysentery, Amebic; Entamoeba histolytica; Female; L | 1983 |
Comparative efficacy of metronidazole and another 5-nitroimidazole, CG-10213-Go, in caecal amoebiasis in albino mice (Mus musculus).
Topics: Amebicides; Animals; Cecal Diseases; Dysentery, Amebic; Metronidazole; Mice; Nitroimidazoles | 1982 |
Use of antibiotics to prevent hepatitis and typhlitis in male scid mice spontaneously infected with Helicobacter hepaticus.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Bismuth; Cecal Diseases; Cecum; Chronic Disease; Helico | 1995 |
A comparative study of experimental caecal amoebiasis and the evaluation of amoebicides.
Topics: Amebicides; Animals; Cecal Diseases; Cricetinae; Disease Models, Animal; Entamoeba histolytica; Enta | 1995 |
The use of metronidazole in treating complications of amebiasis.
Topics: Adult; Cecal Diseases; Cecum; Dysentery, Amebic; Humans; Intestinal Diseases, Parasitic; Liver Absce | 1974 |
Laboratory evaluation of panidazole (1-(2'-( -pyridyl) ethyl-2-methyl)-5-nitroimidazole), a new amoebicide.
Topics: Amebiasis; Amebicides; Animals; Antitrichomonal Agents; Cecal Diseases; Cricetinae; Emetine; Entamoe | 1972 |
Studies of human amebiasis. 3. Ameboma: a radiologic manifestation of amebic colitis.
Topics: Adolescent; Adult; Barium Sulfate; Biopsy; Cecal Diseases; Cecum; Colitis; Colon; Colonic Neoplasms; | 1973 |
Intestinal amebiasis. A roentgen analysis of 19 cases including 2 case reports.
Topics: Abscess; Aged; Cecal Diseases; Colitis, Ulcerative; Colonic Diseases; Colonic Neoplasms; Diagnosis, | 1974 |