metronidazole has been researched along with Cat Diseases in 32 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cat Diseases: Diseases of the domestic cat (Felis catus or F. domesticus). This term does not include diseases of the so-called big cats such as CHEETAHS; LIONS; tigers, cougars, panthers, leopards, and other Felidae for which the heading CARNIVORA is used.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Inefficiency of metronidazole is commonly reported in the veterinary clinic routine in the treatment of giardiasis in dogs and cats." | 7.77 | Secnidazole for the treatment of giardiasis in naturally infected cats. ( Bertoletti, B; Brendler, S; Castro, VS; Costa, MM; Da Silva, AS; Jaques, JA; Lopes, ST; Mazzanti, CM; Monteiro, SG; Raiser, AG; Tonin, AA; Zanette, RA, 2011) |
| "There are several drugs available for the treatment of giardiasis in cats, including metronidazole." | 7.72 | Metronidazole for the treatment of feline giardiasis. ( Lappin, MR; Scorza, AV, 2004) |
| "Previous studies have demonstrated that fidaxomicin, a macrocyclic lactone antibiotic used to treat recurrent Clostridioides difficile-associated diarrhea, also displays potent in vitro bactericidal activity against Clostridium perfringens strains isolated from humans." | 4.31 | In vitro activity of fidaxomicin and combinations of fidaxomicin with other antibiotics against Clostridium perfringens strains isolated from dogs and cats. ( Álvarez-Pérez, S; Anega, B; Blanco, JL; García, ME; Hernández, M, 2023) |
| " Inefficiency of metronidazole is commonly reported in the veterinary clinic routine in the treatment of giardiasis in dogs and cats." | 3.77 | Secnidazole for the treatment of giardiasis in naturally infected cats. ( Bertoletti, B; Brendler, S; Castro, VS; Costa, MM; Da Silva, AS; Jaques, JA; Lopes, ST; Mazzanti, CM; Monteiro, SG; Raiser, AG; Tonin, AA; Zanette, RA, 2011) |
| "There are several drugs available for the treatment of giardiasis in cats, including metronidazole." | 3.72 | Metronidazole for the treatment of feline giardiasis. ( Lappin, MR; Scorza, AV, 2004) |
| " The highest serum MTZ concentration observed 1 hour after dosing was 36 μg/mL." | 3.11 | Genotoxicity from metronidazole detected in vitro, but not in vivo, in healthy dogs in a randomized clinical trial. ( Manley, CI; Peterson, HM; Pritchard, JC; Trepanier, LA, 2022) |
| " The terminal half-life was 5." | 1.35 | Single-dose pharmacokinetics and genotoxicity of metronidazole in cats. ( Goldstein, RE; McDonough, SP; Papich, M; Ramstead, K; Rishniw, M; Schwark, WS; Sekis, I; Simpson, KW, 2009) |
| "The mean prepatent period for Giardia infection in 7 cats was 9." | 1.27 | Feline giardiasis: observations on natural and induced infections. ( Farrell, JP; Kirkpatrick, CE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.00) | 18.7374 |
| 1990's | 4 (12.50) | 18.2507 |
| 2000's | 11 (34.38) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Peterson, HM | 1 |
| Manley, CI | 1 |
| Trepanier, LA | 1 |
| Pritchard, JC | 1 |
| Belchik, SE | 1 |
| Oba, PM | 1 |
| Wyss, R | 1 |
| Asare, PT | 1 |
| Vidal, S | 1 |
| Miao, Y | 1 |
| Adesokan, Y | 1 |
| Suchodolski, JS | 1 |
| Swanson, KS | 1 |
| Adebowale, OO | 1 |
| Jimoh, AB | 1 |
| Adebayo, OO | 1 |
| Alamu, AA | 1 |
| Adeleye, AI | 1 |
| Fasanmi, OG | 1 |
| Olasoju, M | 1 |
| Olagunju, PO | 1 |
| Fasina, FO | 1 |
| Álvarez-Pérez, S | 1 |
| Anega, B | 1 |
| Blanco, JL | 1 |
| Hernández, M | 1 |
| García, ME | 1 |
| Jung, J | 1 |
| Choi, M | 1 |
| Trepanier, L | 1 |
| Sekis, I | 1 |
| Ramstead, K | 1 |
| Rishniw, M | 1 |
| Schwark, WS | 1 |
| McDonough, SP | 1 |
| Goldstein, RE | 1 |
| Papich, M | 1 |
| Simpson, KW | 1 |
| Khoshnegah, J | 1 |
| Jamshidi, S | 1 |
| Mohammadi, M | 1 |
| Sasani, F | 1 |
| Langner, KF | 1 |
| Schenk, HC | 1 |
| Leithaeuser, C | 1 |
| Tholen, H | 1 |
| Simon, D | 1 |
| Da Silva, AS | 1 |
| Castro, VS | 1 |
| Tonin, AA | 1 |
| Brendler, S | 1 |
| Costa, MM | 1 |
| Jaques, JA | 1 |
| Bertoletti, B | 1 |
| Zanette, RA | 1 |
| Raiser, AG | 1 |
| Mazzanti, CM | 1 |
| Lopes, ST | 1 |
| Monteiro, SG | 1 |
| Nagel, R | 1 |
| Cuttell, L | 1 |
| Stensvold, CR | 1 |
| Mills, PC | 1 |
| Bielefeldt-Ohmann, H | 1 |
| Traub, RJ | 1 |
| Jergens, AE | 1 |
| Polizopoulou, ZS | 1 |
| Kazakos, G | 1 |
| Georgiadis, G | 1 |
| Soubasis, N | 1 |
| Koutinas, Ch | 1 |
| Koutinas, AF | 1 |
| Baral, RM | 1 |
| Catt, MJ | 1 |
| Malik, R | 1 |
| Scorza, AV | 1 |
| Lappin, MR | 1 |
| Van den Bulck, K | 1 |
| Decostere, A | 1 |
| Gruntar, I | 1 |
| Baele, M | 1 |
| Krt, B | 1 |
| Ducatelle, R | 1 |
| Haesebrouck, F | 1 |
| Olson, EJ | 1 |
| Morales, SC | 1 |
| McVey, AS | 1 |
| Hayden, DW | 1 |
| Kirkpatrick, CE | 2 |
| Farrell, JP | 1 |
| Brodrick, TW | 1 |
| Shatto, NL | 1 |
| Rohner, K | 1 |
| Demuth, D | 1 |
| Meyer, EK | 1 |
| Neiger, R | 1 |
| Seiler, G | 1 |
| Schmassmann, A | 1 |
| Romatowski, J | 1 |
| Caiafa, AM | 1 |
| Weese, JS | 1 |
| Weese, HE | 1 |
| Bourdeau, TL | 1 |
| Staempfli, HR | 1 |
| Willard, MD | 1 |
| Dow, SW | 1 |
| Zimmer, JF | 1 |
| Laczak, JP | 1 |
| Trought, VP | 1 |
| Dean, TS | 1 |
| Shinn, DL | 1 |
| McFadzean, JA | 1 |
| Squires, SL | 1 |
4 reviews available for metronidazole and Cat Diseases
| Article | Year |
|---|---|
Idiopathic inflammatory bowel disease in cats. Rational treatment selection.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Cat Diseases; Cats; Comorbidity; Evidence- | 2009 |
Feline inflammatory bowel disease--current perspectives on etiopathogenesis and therapy.
Topics: Adrenal Cortex Hormones; Animal Nutritional Physiological Phenomena; Animals; Azathioprine; Cat Dise | 2002 |
Feline inflammatory bowel disease: a review.
Topics: Animals; Cat Diseases; Cats; Diet; Inflammatory Bowel Diseases; Metronidazole; Prednisolone | 1999 |
Management of anaerobic infections.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Cat Diseases; Cats; Combi | 1988 |
1 trial available for metronidazole and Cat Diseases
| Article | Year |
|---|---|
Genotoxicity from metronidazole detected in vitro, but not in vivo, in healthy dogs in a randomized clinical trial.
Topics: Animals; Cat Diseases; Cats; DNA Damage; Dog Diseases; Dogs; Metronidazole | 2022 |
27 other studies available for metronidazole and Cat Diseases
| Article | Year |
|---|---|
Effects of a milk oligosaccharide biosimilar on fecal characteristics, microbiota, and bile acid, calprotectin, and immunoglobulin concentrations of healthy adult dogs treated with metronidazole.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Bile Acids and Salts; Biosimilar Pharmaceuticals; Cat D | 2023 |
Evaluation of antimicrobial usage in companion animals at a Veterinary Teaching Hospital in Nigeria.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Hospi | 2023 |
In vitro activity of fidaxomicin and combinations of fidaxomicin with other antibiotics against Clostridium perfringens strains isolated from dogs and cats.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clindamycin; Clostridioides difficile; Clostridi | 2023 |
Nonsurgical resolution of caudal mediastinal paraesophageal abscess in a cat.
Topics: Abscess; Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Cat Diseases | 2015 |
Single-dose pharmacokinetics and genotoxicity of metronidazole in cats.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Infective Agents; Cat Diseases; Cats; Cell | 2009 |
The efficacy and safety of long-term Helicobacter species quadruple therapy in asymptomatic cats with naturally acquired infection.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clarithromycin; DNA, Bacterial; Dru | 2011 |
Localised tetanus in a cat.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clostridium tetani; Debridement; Electromyograph | 2011 |
Secnidazole for the treatment of giardiasis in naturally infected cats.
Topics: Animals; Antiprotozoal Agents; Blood Chemical Analysis; Brazil; Cat Diseases; Cats; Feces; Female; G | 2011 |
Blastocystis subtypes in symptomatic and asymptomatic family members and pets and response to therapy.
Topics: Adult; Aged; Animals; Antiprotozoal Agents; Asymptomatic Diseases; Biopsy; Blastocystis; Blastocysti | 2012 |
Presumed localized tetanus in two cats.
Topics: Animals; Cat Diseases; Cats; Diagnosis, Differential; Diazepam; Electromyography; Forelimb; Male; Me | 2002 |
What is your diagnosis? Localised tetanus in a cat.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clostridium tetani; Diagnosis, Differential; Ele | 2002 |
Metronidazole for the treatment of feline giardiasis.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Cat Diseases; Cats; Female; Giardia; Giardiasis | 2004 |
In vitro antimicrobial susceptibility testing of Helicobacter felis, H. bizzozeronii, and H. salomonis.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Drug Resistance, Bacterial; | 2005 |
Putative metronidazole neurotoxicosis in a cat.
Topics: Animals; Anti-Infective Agents; Brain Stem; Cat Diseases; Cats; Central Nervous System Diseases; Met | 2005 |
Feline giardiasis: observations on natural and induced infections.
Topics: Animals; Cat Diseases; Cats; Feces; Furazolidone; Gerbillinae; Giardia; Giardiasis; Intestinal Disea | 1984 |
Treatment of empyema in a cat.
Topics: Animals; Cat Diseases; Cats; Empyema; Male; Metronidazole | 1983 |
Feline giardiasis (a case report).
Topics: Animals; Cat Diseases; Cats; Giardiasis; Male; Metronidazole | 1981 |
[Adverse effects of veterinary drugs].
Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Dipyrone; Dog Diseases; Dogs; Drug Combinations; | 1994 |
Adverse events associated with albendazole and other products used for treatment of giardiasis in dogs.
Topics: Adverse Drug Reaction Reporting Systems; Albendazole; Animals; Anthelmintics; Antiprotozoal Agents; | 1998 |
Use of a urea breath test to evaluate short-term treatments for cats naturally infected with Helicobacter heilmannii.
Topics: Animals; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Azithromycin; B | 1999 |
Pentatrichomonas hominis infection in four kittens.
Topics: Animals; Anti-Infective Agents; Antitrichomonal Agents; Cat Diseases; Cats; Colon; Diarrhea; Enroflo | 2000 |
In vitro antimicrobial susceptibilities of three Porphyromonas spp and responses in the oral cavity of cats to treatment with selected antimicrobial drugs.
Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Cat Diseases; Cats; Clindamycin; Doxycycl | 2000 |
Suspected Clostridium difficile-associated diarrhea in two cats.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Clostridioides difficile; Diarrhea; Enterocoliti | 2001 |
Treatment of feline giardiasis with metronidazole.
Topics: Animals; Cat Diseases; Cats; Feces; Giardiasis; Intestinal Diseases, Parasitic; Metronidazole | 1987 |
Giardiasis in a cattery.
Topics: Animals; Cat Diseases; Cats; Diarrhea; Disinfection; Furazolidone; Giardiasis; Metronidazole; Sodium | 1985 |
Treatment for cystitis.
Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Cystitis; Female; Metronidazole | 1973 |
Metronidazole in the treatment of gingivitis.
Topics: Animals; Cat Diseases; Cats; Dog Diseases; Dogs; Gingivitis; Metronidazole | 1969 |