metronidazole has been researched along with Cardiovascular Diseases in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liao, S | 1 |
| Yang, W | 1 |
| Yu, T | 1 |
| Dai, L | 1 |
| Liu, X | 1 |
| Zhang, J | 1 |
| Zhao, J | 1 |
| Liu, C | 1 |
| Ye, Z | 1 |
| Cao, Y | 1 |
| Miao, C | 1 |
| Liu, W | 1 |
| Dong, L | 1 |
| Lv, Z | 1 |
| Iheozor-Ejiofor, Z | 1 |
| Li, C | 1 |
| Goyal, L | 1 |
| Gupta, S | 1 |
| Dewan, M | 1 |
| Singla, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Non-surgical Periodontal Treatment on Plasma Fibrinogen, Plasminogen Activator Inhibitor 1 and C-reactive Protein Levels in Cardiovascular Disease Patients With Periodontitis[NCT04305171] | 28 participants (Actual) | Observational [Patient Registry] | 2018-04-06 | Completed | |||
| A Randomized Control Trial of Comprehensive Oral Intervention in Patients With Acute Myocardial Infarction: a Pilot Study[NCT04012541] | 68 participants (Anticipated) | Interventional | 2019-07-05 | Recruiting | |||
| Systemic Effects of Periodontal Therapy on Patients With Ischemic Stroke. A Pilot Randomized Controlled Clinical Trial[NCT04956211] | 60 participants (Anticipated) | Interventional | 2021-09-29 | Enrolling by invitation | |||
| The Effects of Non-Surgical Periodontal Therapy on Neutrophil Elastase and Elastase Alpha-1 Proteinase Inhibitor Levels in GCF in Periodontitis Patients With or Without Acute Coronary Syndrome[NCT04785235] | 43 participants (Actual) | Observational [Patient Registry] | 2007-10-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for metronidazole and Cardiovascular Diseases
| Article | Year |
|---|---|
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Periodontal therapy for primary or secondary prevention of cardiovascular disease in people with periodontitis.
Topics: Amoxicillin; Anti-Bacterial Agents; Cardiovascular Diseases; Chronic Periodontitis; Humans; Metaboli | 2022 |
Is periodontal therapy an effective treatment modality for preventing or managing cardiovascular disease in patients with periodontitis?
Topics: Amoxicillin; Cardiovascular Diseases; Chronic Periodontitis; Female; Humans; Lactation; Metronidazol | 2023 |
1 other study available for metronidazole and Cardiovascular Diseases
| Article | Year |
|---|---|
Establishment of a Drug Screening Model for Cardiac Complications of Acute Renal Failure.
Topics: Acute Kidney Injury; Animals; Animals, Genetically Modified; Cardio-Renal Syndrome; Cardiovascular D | 2021 |