metronidazole has been researched along with Cancer of Cervix in 45 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Excerpt | Relevance | Reference |
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"Results are reported of a clinical trial on the effect of metronidazole as an adjuvant radiosensitizer in the radiation treatment of cervix carcinomas in advanced stages." | 5.06 | Anaemia as a prognostic factor for the therapeutic effect of radiosensitizers. ( Balmukhanov, SB; Révész, L, 1987) |
"Indices of platelet function, plasmic coagulation and fibrinolysis were studied during gamma-beam therapy in patients with laryngeal, gastric and cervical tumors (potentially at risk for thrombosis) against a background of metronidazole administration." | 3.67 | [Hemostasis in cancer patients during radiation therapy using metronidazole]. ( Andreev, VG; Berdov, BA; Chekalina, SI; Pavlov, VV, 1989) |
"So a study was undertaken in various cancer patients to observe the role of metrnidazole as a selective radiosensitizer." | 2.67 | Role of metronidazole in radiation therapy (a review of 717 cancer cases). ( Acharya, DK, 1994) |
"Nonalcoholic Wernicke's encephalopathy may share a similar metabolic pathway with MIE, resulting in difficulties in diagnosis." | 2.48 | Metronidazole-induced Encephalopathy: Case Report and Review Literature. ( Chen, LA; Cheng, SJ; Huang, YT, 2012) |
"Four patients had had cervical cancer, five had uterine cancer, one had prostatic cancer, one had vesical cancer and one had vaginal cancer." | 1.37 | A novel treatment for haemorrhagic radiation proctitis using colonic irrigation and oral antibiotic administration. ( Atittharnsakul, P; Patiwongpaisarn, A; Rojanasakul, A; Sahakitrungruang, C; Thum-Umnuaysuk, S, 2011) |
"The results of radiation treatment for cervical cancer obtained at the Institute Clinic are discussed." | 1.28 | [Effectiveness of radiotherapy of patients with cancer of the cervix uteri at the Central Research Roentgeno-Radiological Institute of the USSR Ministry of Health]. ( Kholin, VV; Zharinov, GM, 1989) |
"The paper summarizes the results of dynamic dose-fractionation combined with oxygen breathing at ambient pressure and metronidazole in head and neck, and uterine cervix cancer." | 1.27 | Dynamic dose-fractionation combined with oxygen breathing at ambient pressure and high-dose metronidazole in head and neck, and uterine cervix cancer. ( Boljesíková, E; Durkovský, J; Jancina, J; Kubovcáková, N; Siracká, E, 1983) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (71.11) | 18.7374 |
1990's | 6 (13.33) | 18.2507 |
2000's | 2 (4.44) | 29.6817 |
2010's | 4 (8.89) | 24.3611 |
2020's | 1 (2.22) | 2.80 |
Authors | Studies |
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Ekdahl, L | 1 |
Eoh, KJ | 1 |
Thumuluru, KM | 1 |
Butler-Manuel, SA | 1 |
Tae Kim, Y | 1 |
Lönnerfors, C | 1 |
Falconer, H | 1 |
Persson, J | 1 |
Aebischer, B | 1 |
Elsig, S | 1 |
Taeymans, J | 1 |
Pomp, S | 1 |
Kuhness, D | 1 |
Barcaro, G | 1 |
Sementa, L | 1 |
Mankad, V | 1 |
Fortunelli, A | 1 |
Sterrer, M | 1 |
Netzer, FP | 1 |
Surnev, S | 1 |
Schmieder, AH | 1 |
Caruthers, SD | 1 |
Keupp, J | 1 |
Wickline, SA | 1 |
Lanza, GM | 1 |
Lowe, J | 1 |
Wodarcyk, AJ | 1 |
Floyd, KT | 1 |
Rastogi, N | 1 |
Schultz, EJ | 1 |
Swager, SA | 1 |
Chadwick, JA | 1 |
Tran, T | 1 |
Raman, SV | 1 |
Janssen, PM | 1 |
Rafael-Fortney, JA | 1 |
Alcalay, RN | 1 |
Levy, OA | 1 |
Wolf, P | 1 |
Oliva, P | 1 |
Zhang, XK | 1 |
Waters, CH | 1 |
Fahn, S | 1 |
Kang, U | 1 |
Liong, C | 1 |
Ford, B | 1 |
Mazzoni, P | 1 |
Kuo, S | 1 |
Johnson, A | 1 |
Xiong, L | 1 |
Rouleau, GA | 1 |
Chung, W | 1 |
Marder, KS | 1 |
Gan-Or, Z | 1 |
Kamei, K | 1 |
Terao, T | 1 |
Katayama, Y | 1 |
Hatano, K | 1 |
Kodama, K | 1 |
Shirahama, M | 1 |
Sakai, A | 1 |
Hirakawa, H | 1 |
Mizokami, Y | 1 |
Shiotsuki, I | 1 |
Ishii, N | 1 |
Inoue, Y | 1 |
Akboga, MK | 1 |
Yayla, C | 1 |
Balci, KG | 1 |
Ozeke, O | 1 |
Maden, O | 1 |
Kisacik, H | 1 |
Temizhan, A | 1 |
Aydogdu, S | 1 |
Zhu, J | 2 |
Ying, SH | 1 |
Feng, MG | 1 |
Zhang, XG | 1 |
Li, H | 1 |
Wang, L | 1 |
Hao, YY | 1 |
Liang, GD | 1 |
Ma, YH | 1 |
Yang, GS | 1 |
Hu, JH | 1 |
Pfeifer, L | 1 |
Goertz, RS | 1 |
Neurath, MF | 1 |
Strobel, D | 1 |
Wildner, D | 1 |
Lin, JT | 1 |
Yang, XN | 1 |
Zhong, WZ | 1 |
Liao, RQ | 1 |
Dong, S | 1 |
Nie, Q | 1 |
Weng, SX | 1 |
Fang, XJ | 1 |
Zheng, JY | 1 |
Wu, YL | 1 |
Řezanka, T | 1 |
Kaineder, K | 1 |
Mezricky, D | 1 |
Řezanka, M | 1 |
Bišová, K | 1 |
Zachleder, V | 1 |
Vítová, M | 1 |
Rinker, JA | 1 |
Marshall, SA | 1 |
Mazzone, CM | 1 |
Lowery-Gionta, EG | 1 |
Gulati, V | 1 |
Pleil, KE | 1 |
Kash, TL | 1 |
Navarro, M | 1 |
Thiele, TE | 1 |
Zhang, Y | 1 |
Huang, Y | 1 |
Jin, Z | 1 |
Li, X | 1 |
Li, B | 1 |
Xu, P | 1 |
Huang, P | 1 |
Liu, C | 1 |
Fokdal, L | 1 |
Sturdza, A | 1 |
Mazeron, R | 1 |
Haie-Meder, C | 1 |
Tan, LT | 1 |
Gillham, C | 1 |
Šegedin, B | 1 |
Jürgenliemk-Schultz, I | 1 |
Kirisits, C | 1 |
Hoskin, P | 1 |
Pötter, R | 1 |
Lindegaard, JC | 1 |
Tanderup, K | 1 |
Levin, DE | 1 |
Schmitz, AJ | 1 |
Hines, SM | 1 |
Hines, KJ | 1 |
Tucker, MJ | 1 |
Brewer, SH | 1 |
Fenlon, EE | 1 |
Álvarez-Pérez, S | 1 |
Blanco, JL | 1 |
Peláez, T | 1 |
Martínez-Nevado, E | 1 |
García, ME | 1 |
Puckerin, AA | 1 |
Chang, DD | 1 |
Subramanyam, P | 1 |
Colecraft, HM | 1 |
Dogan, H | 1 |
Coteli, E | 1 |
Karatas, F | 1 |
Ceylan, O | 1 |
Sahin, MD | 1 |
Akdamar, G | 1 |
Kryczyk, A | 1 |
Żmudzki, P | 1 |
Hubicka, U | 1 |
Giovannelli, D | 1 |
Chung, M | 1 |
Staley, J | 1 |
Starovoytov, V | 1 |
Le Bris, N | 1 |
Vetriani, C | 1 |
Chen, W | 1 |
Wu, L | 1 |
Liu, X | 1 |
Shen, Y | 1 |
Liang, Y | 1 |
Tan, H | 1 |
Yang, Y | 1 |
Liu, Q | 1 |
Wang, M | 1 |
Liu, L | 1 |
Wang, X | 1 |
Liu, B | 1 |
Liu, GH | 1 |
Zhu, YJ | 1 |
Wang, JP | 1 |
Che, JM | 1 |
Chen, QQ | 1 |
Chen, Z | 1 |
Maucksch, U | 1 |
Runge, R | 1 |
Wunderlich, G | 1 |
Freudenberg, R | 1 |
Naumann, A | 1 |
Kotzerke, J | 1 |
George, R | 1 |
Prasoona, TS | 1 |
Kandasamy, R | 1 |
Cherian, R | 1 |
Celine, T | 1 |
Jeba, J | 1 |
Murali, S | 1 |
Mathew, D | 1 |
Sahakitrungruang, C | 1 |
Thum-Umnuaysuk, S | 1 |
Patiwongpaisarn, A | 1 |
Atittharnsakul, P | 1 |
Rojanasakul, A | 1 |
Huang, YT | 1 |
Chen, LA | 1 |
Cheng, SJ | 1 |
LOCK, FR | 1 |
WALL, JA | 1 |
KAUFMAN, RH | 1 |
CONNERS, JS | 1 |
Neklasova, NIu | 1 |
Zharinov, GM | 4 |
Vinokurov, VL | 1 |
Skrynditsa, GM | 1 |
Tokita, H | 1 |
Tanaka, N | 1 |
Sekimoto, K | 1 |
Ueno, T | 1 |
Okamoto, K | 1 |
Fujimura, S | 1 |
Tsyb, AF | 1 |
Konopliannikov, AG | 1 |
Kudriavtseva, GT | 1 |
Goldobenko, GV | 1 |
Kherkheulidze, ZSh | 1 |
Shchebetenko, IuE | 1 |
Polotskiĭ, BE | 1 |
Kiseleva, ES | 1 |
Dar'ialova, SL | 1 |
Siracká, E | 1 |
Kubovcáková, N | 1 |
Durkovský, J | 1 |
Jancina, J | 1 |
Boljesíková, E | 1 |
Schneider, GT | 1 |
Thomas, GM | 1 |
Rauth, AM | 1 |
Bush, RS | 1 |
Black, BE | 1 |
Cummings, BJ | 1 |
Acharya, DK | 1 |
Connor, JP | 1 |
Elam, G | 1 |
Goldberg, JM | 1 |
Fowler, JF | 1 |
Chapman, JD | 1 |
Beard, CM | 1 |
Noller, KL | 1 |
O'Fallon, WM | 1 |
Kurland, LT | 1 |
Dockerty, MB | 1 |
Borten, M | 1 |
Friedman, EA | 1 |
Minucci, D | 1 |
Guida, G | 1 |
Rabasso, A | 1 |
Dmitrieva, NV | 1 |
Petukhova, IN | 1 |
Dronova, OM | 1 |
Soldatova, NG | 1 |
Chekalina, SI | 2 |
Guseva, LI | 2 |
Tokarev, OIu | 1 |
Karpitskaia, VS | 1 |
Cekalina, SI | 1 |
Berdov, BA | 2 |
Krashevskiĭ, SV | 1 |
Loenko, IuN | 1 |
Polushin, OG | 1 |
Balmukhanov, SB | 6 |
Beisebaev, AA | 2 |
Mustaphin, DS | 1 |
Aitkolova, ZK | 1 |
Kobikova, DH | 1 |
Abdrahmanov, DN | 1 |
Scott, OC | 1 |
Révész, L | 2 |
Kholin, VV | 2 |
Aitkoolova, ZI | 1 |
Mustaphin, JS | 1 |
Philippenko, VI | 1 |
Rismuhamedova, RS | 1 |
Aisarova, AM | 2 |
Abdrahmanov, JN | 1 |
Aĭtkulova, ZK | 2 |
Mustafin, ZhS | 1 |
Rismukhamedova, RS | 4 |
Filippenko, VI | 1 |
Abdrakhmanov, ZhN | 2 |
Revesh, L | 1 |
Pavlov, VV | 1 |
Andreev, VG | 1 |
Khanna, AK | 1 |
Khanna, A | 1 |
Asthana, AK | 1 |
Musapirova, NA | 2 |
Aĭtkulova, Z | 1 |
Khanson, KP | 1 |
Val'kovich, AA | 1 |
Volchkov, VA | 1 |
Shibanova, AI | 1 |
Birzhanova, NKh | 1 |
Toktamysova, ZS | 1 |
McClatchie, S | 1 |
Sambhi, JS | 1 |
Heinz, KP | 1 |
Korte, W | 1 |
Drazancić, A | 1 |
Krstulović, B | 1 |
Ivić, J | 1 |
Wingate, MB | 1 |
Cornes, JS | 1 |
Chappaz, G | 1 |
Bertrand, P | 1 |
5 reviews available for metronidazole and Cancer of Cervix
Article | Year |
---|---|
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; A | 2016 |
Metronidazole-induced Encephalopathy: Case Report and Review Literature.
Topics: Aged; Female; Humans; Magnetic Resonance Imaging; Mesencephalon; Metronidazole; Middle Aged; Radiati | 2012 |
[Analysis of clinical experience in the use of metronidazole as a radiosensitizer of tumors].
Topics: Brain Neoplasms; Clinical Trials as Topic; Esophageal Neoplasms; Female; Genital Neoplasms, Female; | 1983 |
[Electron acceptor compounds as radiation sensitizers of hypoxic cells in human tumors].
Topics: Brain Neoplasms; Combined Modality Therapy; Esophageal Neoplasms; Female; Head and Neck Neoplasms; H | 1984 |
Hypoxic sensitizers--implications for radiation therapy.
Topics: Animals; Female; Glioblastoma; Humans; Metronidazole; Misonidazole; Neoplasms; Oxygen Consumption; R | 1979 |
8 trials available for metronidazole and Cancer of Cervix
Article | Year |
---|---|
[Use of electron acceptor compounds in radiotherapy].
Topics: Clinical Trials as Topic; Esophageal Neoplasms; Female; Humans; Laryngeal Neoplasms; Metronidazole; | 1983 |
[Analysis of clinical experience in the use of metronidazole as a radiosensitizer of tumors].
Topics: Brain Neoplasms; Clinical Trials as Topic; Esophageal Neoplasms; Female; Genital Neoplasms, Female; | 1983 |
Role of metronidazole in radiation therapy (a review of 717 cancer cases).
Topics: Female; Humans; Metronidazole; Mouth Neoplasms; Neoplasms; Uterine Cervical Neoplasms | 1994 |
Empiric vaginal metronidazole in the management of the ASCUS Papanicolaou smear: a randomized controlled trial.
Topics: Administration, Intravaginal; Adolescent; Adult; Anti-Infective Agents; Carcinoma, Squamous Cell; Ce | 2002 |
Topical infusion of metronidazole in the radiotherapy of tumours of the uterine cervix: interim report on the 2 year survival.
Topics: Administration, Topical; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Metron | 1990 |
Intratumoral and parametrial infusion of metronidazole in the radiotherapy of uterine cervix cancer: preliminary report.
Topics: Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Metronidazole; Random Allocatio | 1989 |
Anaemia as a prognostic factor for the therapeutic effect of radiosensitizers.
Topics: Anemia; Carcinoma; Female; Humans; Metronidazole; Prognosis; Radiation-Sensitizing Agents; Uterine C | 1987 |
[Hemoglobin level--a prognostic factor of the effectiveness of metronidazole in radiotherapy of cancer of the cervix uteri].
Topics: Anemia; Clinical Trials as Topic; Female; Hemoglobins; Humans; Metronidazole; Middle Aged; Prognosis | 1986 |
33 other studies available for metronidazole and Cancer of Cervix
Article | Year |
---|---|
A combination of second trimester oral metronidazole and no sexual intercourse during second and third trimester may reduce late miscarriage and premature delivery after fertility sparing radical trachelectomy.
Topics: Abortion, Spontaneous; Coitus; Female; Fertility Preservation; Humans; Metronidazole; Neoplasm Recur | 2021 |
Improving malodour management in advanced cancer: a 10-year retrospective study of topical, oral and maintenance metronidazole.
Topics: Administration, Cutaneous; Administration, Oral; Anti-Infective Agents; Female; Head and Neck Neopla | 2017 |
A novel treatment for haemorrhagic radiation proctitis using colonic irrigation and oral antibiotic administration.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Combined Modality Therapy; Female; Ga | 2011 |
GYNECOLOGY AND OBSTETRICS.
Topics: Congenital Abnormalities; Endometriosis; Female; Fetal Diseases; Gynecology; Humans; Maternal-Fetal | 1964 |
CARCINOMA IN SITU OF THE CERVIX.
Topics: Carcinoma in Situ; Carcinoma, Squamous Cell; Cytodiagnosis; Female; Fluorescent Antibody Technique; | 1964 |
[Combined use of local and systemic radiomodifiers as a new modality of cervical carcinoma therapy].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Dimethyl Sulfoxide; Female; | 2006 |
Experimental model for combination chemotherapy with metronidazole using human uterine cervical carcinomas transplanted into nude mice.
Topics: Animals; Bleomycin; Carcinoma, Squamous Cell; Disease Models, Animal; Drug Therapy, Combination; Fem | 1980 |
Dynamic dose-fractionation combined with oxygen breathing at ambient pressure and high-dose metronidazole in head and neck, and uterine cervix cancer.
Topics: Cobalt Radioisotopes; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Metronidaz | 1983 |
Vaginal infections. How to identify and treat them.
Topics: Adolescent; Adult; Candidiasis; Child; Chlamydia Infections; Female; Haemophilus Infections; Herpes | 1983 |
A toxicity study of daily dose metronidazole with pelvic irradiation.
Topics: Administration, Oral; Adolescent; Adult; Aged; Carcinoma; Diarrhea; Dose-Response Relationship, Drug | 1980 |
Developments in radiotherapy other than heavy particle beams.
Topics: Animals; Brain Neoplasms; Energy Transfer; Fast Neutrons; Female; Glioblastoma; Hot Temperature; Hum | 1977 |
Lack of evidence for cancer due to use of metronidazole.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Female; Humans; Lung Neoplasms; Metronidazole; Middle Age | 1979 |
Duration of colposcopic changes associated with trichomonas vaginitis.
Topics: Adult; Colposcopy; Female; Humans; Metronidazole; Papanicolaou Test; Time Factors; Trichomonas Vagin | 1978 |
[Dysplasia and carcinoma in situ of the uterine cervix. Outcome of several cases].
Topics: Adult; Antineoplastic Agents; Carcinoma in Situ; Female; Humans; Metronidazole; Nystatin; Precancero | 1975 |
[Cefoperazone in combination with metronidazole in the prevention of postoperative infectious complications in patients with genital neoplasms].
Topics: Adult; Aged; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Cefoperazone; Drug Admini | 1992 |
[The prevention of radiation complications by using metronidazole experimentally and in the oncology clinic].
Topics: Animals; Combined Modality Therapy; Drug Evaluation; Drug Evaluation, Preclinical; Female; Male; Met | 1991 |
[The hemostatic homeostasis of patients with malignant neoplasms of the larynx, stomach and uterine cervix during radiotherapy and radiosensitization with metronidazole].
Topics: Combined Modality Therapy; Female; Hemostasis; Humans; Laryngeal Neoplasms; Metronidazole; Middle Ag | 1990 |
[Radiation pathomorphosis of experimental squamous cell cancer during mono- and polyradiomodifications].
Topics: Animals; Blood Glucose; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Gamma Rays; Glu | 1990 |
[Effectiveness of radiotherapy of patients with cancer of the cervix uteri at the Central Research Roentgeno-Radiological Institute of the USSR Ministry of Health].
Topics: Dimethyl Sulfoxide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Metronid | 1989 |
[Intratumoral and parametric administration of metronidazole in the radiotherapy of cancer of the cervix].
Topics: Adult; Aged; Combined Modality Therapy; Female; Humans; Metronidazole; Middle Aged; Uterine Cervical | 1989 |
[The effect of metronidazole on the radiosensitivity of cancer of the uterine cervix].
Topics: Administration, Rectal; Combined Modality Therapy; Female; Hemoglobins; Humans; Metronidazole; Radia | 1989 |
[Hemostasis in cancer patients during radiation therapy using metronidazole].
Topics: Combined Modality Therapy; Female; Hemostasis; Humans; Laryngeal Neoplasms; Metronidazole; Preoperat | 1989 |
Postirradiation ulcer and topical metronidazole.
Topics: Breast Neoplasms; Carcinoma, Squamous Cell; Female; Humans; Metronidazole; Middle Aged; Radiation In | 1988 |
[Prognostication of the response of malignant tumors of the cervix uteri to irradiation].
Topics: Cobalt Radioisotopes; Female; Humans; Metronidazole; Prognosis; Radiotherapy Dosage; Uterine Cervica | 1986 |
[Local use of metronidazole in dimethyl sulfoxide in the radiation therapy of cervical cancer].
Topics: Administration, Topical; Animals; Combined Modality Therapy; Dimethyl Sulfoxide; Drug Evaluation; Dr | 1987 |
[Pathomorphosis of cervical cancer with different methods of radiation treatment].
Topics: Adenocarcinoma; Brachytherapy; Carcinoma, Squamous Cell; Combined Modality Therapy; Evaluation Studi | 1986 |
[Spectrophotometric study of metronidazole transformations].
Topics: Combined Modality Therapy; Female; Humans; In Vitro Techniques; Metronidazole; Oxidation-Reduction; | 1985 |
Amoebiasis of the cervix uteri.
Topics: Amebiasis; Biopsy; Diagnosis, Differential; Emetine; Entamoeba histolytica; Female; Humans; Malaysia | 1971 |
Amoebic infection of the female genital tract. A report of three cases.
Topics: Adult; Amebiasis; Carcinoma, Squamous Cell; Entamoeba histolytica; Female; Humans; Metronidazole; Mi | 1973 |
[Epidemiology, pathology and clinical aspects of trichomonas vaginalis infection].
Topics: Age Factors; Candidiasis; Carcinoma in Situ; Chronic Disease; Fallopian Tubes; Female; History, 19th | 1973 |
[Vaginal trichomoniasis and cervix uteri changes].
Topics: Antitrichomonal Agents; Biopsy; Carcinoma; Cervix Uteri; Colposcopy; Diagnosis, Differential; Female | 1969 |
Carcinoma in situ in a young primigravida.
Topics: Adult; Biopsy; Carcinoma, Squamous Cell; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complic | 1965 |
[Evolution of the "problem" of trichomoniasis in the past 5 years].
Topics: Coitus; Female; Humans; Metronidazole; Trichomonas Vaginitis; Uterine Cervical Neoplasms | 1966 |