metronidazole has been researched along with Campylobacter Infection in 18 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "50 patients with intractable duodenal ulcer were randomly assigned to 4 weeks of treatment with colloidal bismuth subcitrate (CBS) alone (26 patients) or with amoxicillin and metronidazole (24 patients)." | 5.06 | Cure of duodenal ulcer associated with eradication of Helicobacter pylori. ( Rauws, EA; Tytgat, GN, 1990) |
| "Campylobacter was a major cause of diarrhea in children in two departments in Guatemala; antimicrobial resistance was high, and treatment regimens in the ambulatory setting which included metronidazole and trimethoprim-sulfamethoxazole and lacked oral rehydration were sub-optimal." | 3.80 | Burden of laboratory-confirmed Campylobacter infections in Guatemala 2008-2012: results from a facility-based surveillance system. ( Arvelo, W; Benoit, SR; Henao, O; Lindblade, K; Lopez, B; Moir, JC; Parsons, MB; Reyes, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edson, RS | 1 |
| Litin, SC | 1 |
| Bundrick, JB | 1 |
| Benoit, SR | 1 |
| Lopez, B | 1 |
| Arvelo, W | 1 |
| Henao, O | 1 |
| Parsons, MB | 1 |
| Reyes, L | 1 |
| Moir, JC | 1 |
| Lindblade, K | 1 |
| Issartel, B | 1 |
| Pariset, C | 1 |
| Roure, C | 1 |
| Boibieux, A | 1 |
| Peyramond, D | 1 |
| Becx, MC | 1 |
| Janssen, AJ | 1 |
| Clasener, HA | 1 |
| de Koning, RW | 1 |
| Rauws, EA | 1 |
| Tytgat, GN | 1 |
| George, LL | 2 |
| Borody, TJ | 2 |
| Andrews, P | 1 |
| Devine, M | 1 |
| Moore-Jones, D | 1 |
| Walton, M | 1 |
| Brandl, S | 2 |
| Korovina, NA | 1 |
| Levitskaia, SV | 1 |
| Bokser, GV | 1 |
| Spirina, TS | 1 |
| Taranenko, LA | 1 |
| Safonova, TB | 1 |
| O'Riordan, T | 1 |
| Mathai, E | 1 |
| Tobin, E | 1 |
| McKenna, D | 1 |
| Keane, C | 1 |
| Sweeney, E | 1 |
| O'Morain, C | 1 |
| Graham, DY | 1 |
| Opekun, A | 1 |
| Lew, GM | 1 |
| Evans, DJ | 1 |
| Klein, PD | 1 |
| Evans, DG | 1 |
| Bhatia, RS | 1 |
| Nigam, P | 1 |
| Levi, S | 2 |
| Dollery, CT | 1 |
| Bloom, SR | 1 |
| Calam, J | 2 |
| Cox, TM | 1 |
| Hodgson, HJ | 1 |
| Losowsky, MS | 1 |
| Pepys, MB | 1 |
| Wright, NA | 1 |
| Wrong, OM | 1 |
| Beardshall, K | 1 |
| Swift, I | 1 |
| Foulkes, W | 1 |
| Playford, R | 1 |
| Ghosh, P | 1 |
| Chaĭka, NA | 1 |
| Axon, AT | 1 |
| Cole, P | 1 |
| Noonan, S | 1 |
| Morgan, A | 1 |
| Lenne, J | 1 |
| Hyland, L | 1 |
| Borody, EG | 1 |
| Börsch, G | 2 |
| Rühl, GH | 1 |
| Stebbing, MA | 1 |
| Schache, DJ | 1 |
| Masters, A | 1 |
| Tovey, FI | 1 |
| Rees, M | 1 |
| Howden, A | 1 |
| Boswell, PA | 1 |
2 reviews available for metronidazole and Campylobacter Infection
| Article | Year |
|---|---|
[Campylobacter-induced gastritis].
Topics: Antibodies, Bacterial; Campylobacter; Campylobacter Infections; Furazolidone; Gastritis; Humans; Met | 1989 |
Campylobacter pylori--therapy review.
Topics: Antacids; Anti-Bacterial Agents; Bismuth; Campylobacter Infections; Drug Therapy, Combination; Human | 1989 |
3 trials available for metronidazole and Campylobacter Infection
| Article | Year |
|---|---|
Cure of duodenal ulcer associated with eradication of Helicobacter pylori.
Topics: Administration, Oral; Amoxicillin; Anti-Ulcer Agents; Campylobacter; Campylobacter Infections; Drug | 1990 |
[Comparative evaluation of the effectiveness of the treatment of gastroduodenal Campylobacter infection in children].
Topics: Anti-Infective Agents; Campylobacter Infections; Duodenitis; Furazolidone; Gastroenteritis; Humans; | 1991 |
Recurrence of duodenal ulcer and Campylobacter pylori infection after eradication.
Topics: Administration, Oral; Adult; Aged; Campylobacter Infections; Clinical Trials as Topic; Drug Administ | 1989 |
13 other studies available for metronidazole and Campylobacter Infection
| Article | Year |
|---|---|
Clinical Pearls in Infectious Diseases 2017.
Topics: Administration, Intravaginal; Adult; Aged; Anti-Bacterial Agents; Body Piercing; Campylobacter Infec | 2017 |
Burden of laboratory-confirmed Campylobacter infections in Guatemala 2008-2012: results from a facility-based surveillance system.
Topics: Adolescent; Adult; Ambulatory Care Facilities; Anti-Bacterial Agents; Campylobacter; Campylobacter I | 2014 |
Successful treatment of prosthetic knee infection due to Campylobacter upsaliensis.
Topics: Adult; Anti-Bacterial Agents; Campylobacter; Campylobacter Infections; Ceftriaxone; Cephalosporins; | 2002 |
Metronidazole-resistant Helicobacter pylori.
Topics: Adult; Aged; Campylobacter; Campylobacter Infections; Drug Resistance, Microbial; Female; Gastritis; | 1990 |
Cure of duodenal ulcer after eradication of Helicobacter pylori.
Topics: Adult; Aged; Anti-Ulcer Agents; Campylobacter Infections; Duodenal Ulcer; Duodenitis; Duodenum; Fema | 1990 |
Adjuvant antibiotic therapy in duodenal ulcers treated with colloidal bismuth subcitrate.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Campylobacter Infections; Drug Resistance, Microbial; Drug | 1990 |
Ablation of exaggerated meal-stimulated gastrin release in duodenal ulcer patients after clearance of Helicobacter (Campylobacter) pylori infection.
Topics: Bismuth; Campylobacter Infections; Drug Therapy, Combination; Duodenal Ulcer; Female; Food; Gastrins | 1990 |
Metronidazole in acid peptic disease.
Topics: Amebiasis; Antacids; Campylobacter Infections; Drug Therapy, Combination; Dyspepsia; Humans; Metroni | 1990 |
Campylobacter pylori, duodenal ulcer disease, and gastrin.
Topics: Adult; Antacids; Anti-Ulcer Agents; Campylobacter Infections; Duodenal Ulcer; Gastrins; Humans; Male | 1989 |
Antral Helicobacter pylori, hypergastrinaemia, and duodenal ulcers: effect of eradicating the organism.
Topics: Antacids; Campylobacter; Campylobacter Infections; Duodenal Ulcer; Gastrins; Gastritis; Humans; Metr | 1989 |
[Search for the best procedure for Campylobacter eradication. Results of long-term studies are still unavailable].
Topics: Anti-Ulcer Agents; Campylobacter Infections; Drug Therapy, Combination; Follow-Up Studies; Gastritis | 1989 |
[Morphologic change in Campylobacter pylori associated gastritis in and following successful antibacterial therapy].
Topics: Amoxicillin; Bismuth; Campylobacter Infections; Drug Therapy, Combination; Gastric Mucosa; Gastritis | 1989 |
Metronidazole and Campylobacter pylori infection.
Topics: Campylobacter Infections; Humans; Metronidazole | 1988 |