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metronidazole and Bullous Dermatoses

metronidazole has been researched along with Bullous Dermatoses in 5 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rashid Dar, N1
Raza, N1
Sehgal, VN1
Khandpur, S1
Sardana, K1
Bajaj, P1
Brinkmeier, T1
Herbst, RA1
Schaller, J1
Kuegler, K1
Pirker, C1
Beiteke, U1
Grosshans, E1
Frosch, PJ1
Yawalkar, N1
Reimers, A1
Hari, Y1
Hunziker, T1
Gerber, H1
Müller, U1
Pichler, W1
Grossmann, B1
Jung, K1
Linse, R1

Other Studies

5 other studies available for metronidazole and Bullous Dermatoses

ArticleYear
Drug induced linear IgA disease with unusual features: Koebner phenomenon, local insulin sensitivity and annular blister of the nipples.
    Acta dermatovenerologica Croatica : ADC, 2008, Volume: 16, Issue:4

    Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Butylscopolammonium Bromide; Drug Eruptions; Huma

2008
Bullous fixed drug eruption (BFDE) following per-oral metronidazole.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2003, Volume: 17, Issue:5

    Topics: Administration, Oral; Adult; Biopsy, Needle; Drug Eruptions; Drug Therapy, Combination; Follow-Up St

2003
Drug-induced blaschkitis.
    Acta dermato-venereologica, 2004, Volume: 84, Issue:4

    Topics: Adult; Biopsy, Needle; Drug Eruptions; Drug Interactions; Female; Follow-Up Studies; Humans; Immunoh

2004
Drug-induced linear IgA bullous dermatosis associated with ceftriaxone- and metronidazole-specific T cells.
    Dermatology (Basel, Switzerland), 1999, Volume: 199, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; CD8-Positive T-Lymphocytes; Ceftriaxone; Cell Divisi

1999
[Tubero-pustular demodicosis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:7

    Topics: Adult; Anti-Infective Agents; Dermatitis, Atopic; Drug Combinations; Facial Dermatoses; Female; Hexa

1999