metronidazole has been researched along with Bullous Dermatoses in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rashid Dar, N | 1 |
| Raza, N | 1 |
| Sehgal, VN | 1 |
| Khandpur, S | 1 |
| Sardana, K | 1 |
| Bajaj, P | 1 |
| Brinkmeier, T | 1 |
| Herbst, RA | 1 |
| Schaller, J | 1 |
| Kuegler, K | 1 |
| Pirker, C | 1 |
| Beiteke, U | 1 |
| Grosshans, E | 1 |
| Frosch, PJ | 1 |
| Yawalkar, N | 1 |
| Reimers, A | 1 |
| Hari, Y | 1 |
| Hunziker, T | 1 |
| Gerber, H | 1 |
| Müller, U | 1 |
| Pichler, W | 1 |
| Grossmann, B | 1 |
| Jung, K | 1 |
| Linse, R | 1 |
5 other studies available for metronidazole and Bullous Dermatoses
| Article | Year |
|---|---|
Drug induced linear IgA disease with unusual features: Koebner phenomenon, local insulin sensitivity and annular blister of the nipples.
Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Butylscopolammonium Bromide; Drug Eruptions; Huma | 2008 |
Bullous fixed drug eruption (BFDE) following per-oral metronidazole.
Topics: Administration, Oral; Adult; Biopsy, Needle; Drug Eruptions; Drug Therapy, Combination; Follow-Up St | 2003 |
Drug-induced blaschkitis.
Topics: Adult; Biopsy, Needle; Drug Eruptions; Drug Interactions; Female; Follow-Up Studies; Humans; Immunoh | 2004 |
Drug-induced linear IgA bullous dermatosis associated with ceftriaxone- and metronidazole-specific T cells.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; CD8-Positive T-Lymphocytes; Ceftriaxone; Cell Divisi | 1999 |
[Tubero-pustular demodicosis].
Topics: Adult; Anti-Infective Agents; Dermatitis, Atopic; Drug Combinations; Facial Dermatoses; Female; Hexa | 1999 |