metronidazole has been researched along with Brain Inflammation in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Diouf, MS | 1 |
| Tall, A | 1 |
| Ndiaye, C | 1 |
| Thiam, A | 1 |
| Deguenonvo, R | 1 |
| Ndiaye, M | 1 |
| Aparicio, DV | 1 |
| Bejarano, JIC | 1 |
| de Los Santos, AM | 1 |
| RamÃrez-Cortinas, S | 1 |
| de la O Cavazos, M | 1 |
| Khan, SA | 1 |
| Dutta, P | 1 |
| Chowdhury, P | 1 |
| Borah, J | 1 |
| Topno, R | 1 |
| Mahanta, J | 1 |
| Sevy, A | 1 |
| Moyse, E | 1 |
| Million, M | 1 |
| Battaglia, F | 1 |
| Solaymani-Mohammadi, S | 1 |
| Lam, MM | 1 |
| Zunt, JR | 1 |
| Petri, WA | 1 |
| Vajramani, GV | 1 |
| Akrawi, H | 1 |
| Jones, G | 1 |
| Sparrow, OC | 1 |
6 other studies available for metronidazole and Brain Inflammation
| Article | Year |
|---|---|
Complications of sinusitis: An 80-case series from the ENT and neurosurgery departments of the Fann university hospital center of Dakar, Senegal.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Brain Abscess; Child; Child, Preschool; Cla | 2020 |
Case Report: Granulomatous Amebic Encephalitis due to Acanthamoeba spp. in an Immunocompetent Pediatric Patient.
Topics: Acanthamoeba; Adolescent; Amebiasis; Anti-Infective Agents; Brain Abscess; Encephalitis; Fatal Outco | 2021 |
Co-infection of arboviruses presenting as Acute Encephalitis Syndrome.
Topics: Acute Disease; Adult; Anti-Infective Agents; Brain; Consciousness; Encephalitis; Encephalitis Virus, | 2011 |
Central and peripheral neurotoxicity of metronidazole after treatment for brain abscess.
Topics: Anti-Infective Agents; Brain Abscess; Encephalitis; Humans; Male; Metronidazole; Neuritis; Young Adu | 2011 |
Entamoeba histolytica encephalitis diagnosed by PCR of cerebrospinal fluid.
Topics: Adult; Antiprotozoal Agents; DNA, Protozoan; Encephalitis; Entamoebiasis; Humans; Male; Metronidazol | 2007 |
Primary ventriculitis caused by Streptococcus intermedius.
Topics: Anti-Infective Agents; Cefotaxime; Cerebral Ventricles; Encephalitis; Endoscopy; Glasgow Coma Scale; | 2007 |