Page last updated: 2024-10-31

metronidazole and Brain Disorders

metronidazole has been researched along with Brain Disorders in 74 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"Metronidazole (MNZ) is a widely used drug for protozoan and anaerobic infections."7.01[A case of irreversible metronidazole encephalopathy during liver abscess treatment]. ( Aoki, Y; Hirosawa, T; Imai, Y; Kashimura, H; Konno, N; Munakata, A; Nihei, T; Okawara, K; Takahashi, S; Usami, Y, 2023)
"Metronidazole is a widely used antibiotic against anaerobic bacteria and protozoa."5.42[Metronidazole-Induced Encephalopathy during Brain Abscess Treatment:Two Case Reports]. ( Asaoka, K; Itamoto, K; Kobayashi, S; Shimbo, D; Sugiyama, T; Uchida, K; Yokoyama, Y, 2015)
"Encephalopathy is a disorder characterized by altered brain function, which can be attributed to various causes."5.37Metronidazole-induced encephalopathy in a patient with liver cirrhosis. ( Cheong, HC; Cho, EY; Cho, YB; Jeong, TG; Kim, HC; Kim, TH; Yang, BJ, 2011)
" Lumbar spinal magnetic resonance imaging (MRI) revealed infective spondylitis, and metronidazole (1."4.31Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report. ( Cha, S; Cho, KH; Lee, BC; Moon, CW, 2023)
" She was transferred from an outside facility where she was treated with 3 courses of metronidazole for diagnosed Clostridium difficile colitis and presumed reoccurrences."3.85Case Report of Metronidazole-Induced Encephalopathy. ( Clements, A, 2017)
"A 38-year-old white woman (weight, 45 kg) received metronidazole among other medications to treat osteomyelitis for 74 days after surgery to correct a spinal neuroarthropathy."3.76Irreversible encephalopathy after treatment with high-dose intravenous metronidazole. ( Groothoff, MV; Hofmeijer, J; Meulenbelt, J; Sikma, MA, 2010)
"Metronidazole (MNZ) is a widely used drug for protozoan and anaerobic infections."3.01[A case of irreversible metronidazole encephalopathy during liver abscess treatment]. ( Aoki, Y; Hirosawa, T; Imai, Y; Kashimura, H; Konno, N; Munakata, A; Nihei, T; Okawara, K; Takahashi, S; Usami, Y, 2023)
"Metronidazole-induced encephalopathy should be considered in patients presenting with neurological symptoms in relation to newly initiated or prolonged metronidazole treatment."2.66Metronidazole-induced encephalopathy: a systematic review. ( Amin, FM; Karlsson, WK; Lindelof, M; Sørensen, CG, 2020)
"Metronidazole is an antibiotic classically used against most anaerobic bacteria and protozoa."2.52[Clinical Characteristics of Metronidazole-induced Encephalopathy: A Report of Two Cases and a Review of 32 Japanese Cases in the Literature]. ( Kaneko, T; Kato, H; Mori, M; Sosa, H, 2015)
"Metronidazole is a common and widely used antibiotic to treat a wide range of infectious diseases and has been associated with serious neurologic disturbances which in some cases were irreversible."1.91Diffuse subcortical white matter restriction: An uncommon finding on metronidazole toxicity. ( Ashourizadeh, H; Etemadifar, M; Salari, M, 2023)
"Metronidazole is a widely used antibiotic against bacterial and protozoan infections."1.62Metronidazole Induced Cerebellar Toxicity: A Case Report. ( Dhungana, K; Niroula, A; Prajapati, R; Sapkota, S; Sharma, S, 2021)
"Metronidazole was stopped."1.56Isolated involvement of corpus callosum in metronidazole-induced encephalopathy with concomitant peripheral neuropathy: A case report. ( Liu, S; Peng, Q; You, Q; Zhang, J, 2020)
"Metronidazole-induced encephalopathy (MIE) is a rare disease caused by an adverse reaction to metronidazole (MNZ)."1.56The pharmacokinetics of oral metronidazole in patients with metronidazole-induced encephalopathy undergoing maintenance hemodialysis. ( Aichi, M; Fukui, R; Ikawa, K; Kuragano, T; Masumoto, M; Mihara, Y; Mimura, Y; Morikawa, N; Okamoto, R; Takesue, Y; Ueda, T; Yahiro, M, 2020)
"Metronidazole induced encephalopathy is a rare central nervous system toxicity, which may be completely reversible with prompt cessation of metronidazole usage."1.51Metronidazole induced encephalopathy: case report and discussion on the differential diagnoses, in particular, Wernicke's encephalopathy. ( Goh, CK; Hou, W; Yiin, RSZ, 2019)
"We infer that the progression of encephalopathy is related to the delayed toxicity caused by high dose or concentration of metronidazole."1.51A case of methylprednisolone treatment for metronidazole-induced encephalopathy. ( Li, L; Li, W; Liang, S; Tang, X; Wu, M; Zhu, Q, 2019)
"In exceptional cases, an encephalopathy with characteristic lesions on magnetic resonance imaging (MRI), usually located in the cerebellum and splenium of the corpus callosum, may be an adverse effect."1.51[Metronidazole-induced encephalopathy: description of a case with radiological and anatomopathological findings]. ( de la Fuente-Bobillo, MA; Gonzalez-Gonzalez, D; Gonzalez-Nafria, N; Martinez-Velasco, E; Ortega-Valin, F; Rojo-Lopez, A; Tola-Arribas, MA, 2019)
"Encefalopathy as a side effect of metronidazole therapy - a case report  Neurological symptoms as side effects of pharmacological treatment generally tend to remain underdiagnosed."1.46[Encefalopathy as a side effect of metronidazole therapy – a case report]. ( Karayianni, M; Laska, AC; von Heijne, A, 2017)
"Metronidazole is a nitroimidazole antimicrobial drug prescribed to treat infections caused by anaerobic bacteria and protozoa."1.42Metronidazole-induced encephalopathy: not always a reversible situation. ( Buckwalter, MS; Finley Caulfield, A; Fischbein, N; Hobbs, K; Stern-Nezer, S, 2015)
"This case report highlights encephalopathy as a complication of prolonged metronidazole treatment, which has become more common in clinical practice for the treatment of C."1.42Metronidazole-induced encephalopathy after prolonged metronidazole course for treatment of C. difficile colitis. ( Dapaah-Afriyie, K; Finn, A; Godfrey, MS; Zainah, H, 2015)
"Metronidazole is a widely used antibiotic against anaerobic bacteria and protozoa."1.42[Metronidazole-Induced Encephalopathy during Brain Abscess Treatment:Two Case Reports]. ( Asaoka, K; Itamoto, K; Kobayashi, S; Shimbo, D; Sugiyama, T; Uchida, K; Yokoyama, Y, 2015)
"Metronidazole-induced encephalopathy (MIE) is a rare cause of drug-induced toxic encephalopathy."1.42Metronidazole-Induced Encephalopathy in Chronic Diarrhoea. ( Haridas, A; Joshi, AR; Moulick, ND; Trivedi, TH, 2015)
"Metronidazole can produce neurological complications although it is not a common scenario."1.40Metronidazole-induced encephalopathy: an uncommon scenario. ( Chakrabarti, S; Pan, K, 2014)
"Encephalopathy is a disorder characterized by altered brain function, which can be attributed to various causes."1.37Metronidazole-induced encephalopathy in a patient with liver cirrhosis. ( Cheong, HC; Cho, EY; Cho, YB; Jeong, TG; Kim, HC; Kim, TH; Yang, BJ, 2011)
"Metronidazole is a 5-nitroimidazole compound known as an antimicrobial agent widely used for the treatment of protozoal infection, anaerobic infection, Helicobacter pylori infection and hepatic encephalopathy."1.33[Two cases of metronidazole-induced encephalopathy]. ( Byun, WM; Choi, JW; Chung, MK; Jang, BI; Kim, JH; Kim, KH; Kim, TD; Kim, TN; Lee, EJ; Lee, HJ; Lee, JY; Oh, HA; Paek, JH, 2005)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19906 (8.11)18.7374
1990's3 (4.05)18.2507
2000's7 (9.46)29.6817
2010's41 (55.41)24.3611
2020's17 (22.97)2.80

Authors

AuthorsStudies
Matsuura, H1
Katayama, T1
Deguchi, K1
Sapkota, S1
Niroula, A1
Prajapati, R1
Sharma, S1
Dhungana, K1
Salari, M1
Etemadifar, M1
Ashourizadeh, H1
Huang, YT1
Sun, CY1
Chang, CM1
Lai, CC1
Hosaka, T1
Terada, M1
Okubo, K1
Iwabuchi, S1
Kajii, E1
Miki, Y2
Takeuchi, Y2
Murasawa, S2
Takayasu, S2
Tsushima, F2
Kakeda, S2
Mizukami, H2
Wakabayashi, K2
Cha, S1
Lee, BC1
Moon, CW1
Cho, KH1
Usami, Y1
Munakata, A1
Takahashi, S1
Konno, N1
Imai, Y1
Okawara, K1
Hirosawa, T1
Aoki, Y1
Kashimura, H1
Nihei, T1
Guijarro-Castro, C1
Sun, Y1
Overby, PJ1
Mehta, H1
Omrani, A1
Rohani, M1
Hosseinpour, S1
Tavasoli, AR1
Chang, MY1
Borchert, MS1
Patel, L1
Batchala, P1
Almardawi, R1
Morales, R1
Raghavan, P1
Hou, W1
Yiin, RSZ1
Goh, CK1
Peng, Q1
You, Q1
Zhang, J1
Liu, S1
Muir, RT1
Mercado, M1
Walter, VR1
Singhal, N1
Kwan, P1
Kucharczyk, W1
Stall, NM1
Carlen, PL1
Mathew, RP1
Kunhimohammed, SP1
Joseph, M1
Mimura, Y1
Yahiro, M1
Masumoto, M1
Fukui, R1
Okamoto, R1
Aichi, M1
Mihara, Y1
Ueda, T1
Takesue, Y1
Ikawa, K1
Morikawa, N1
Kuragano, T1
Karayianni, M1
von Heijne, A1
Laska, AC1
Iwadate, D1
Sato, K1
Kanzaki, M1
Komiyama, C1
Watanabe, C1
Eguchi, T1
Uesaka, Y1
Giraud, N1
Ripault-Cesbron, H1
Cottier, JP1
Dardaine-Giraud, V1
Clements, A1
Taniyama, D1
Maruki, T1
Vitturi, BK1
da Silva Júnior, RG1
da Rocha, AJ1
Narimatsu, K1
Rizvi, I1
Garg, RK1
Kumar, N1
Pandey, S1
Malhotra, HS1
Sørensen, CG1
Karlsson, WK1
Amin, FM1
Lindelof, M1
Ueno, T1
Ito, M1
Arai, A1
Suzuki, C1
Tomiyama, M1
Iemura, T1
Kitano, T1
Ishii, A1
Hishizawa, M1
Kondo, T1
Yamashita, K1
Takaori-Kondo, A1
Kuriyama, A2
Jackson, JL1
Li, L1
Tang, X1
Li, W1
Liang, S1
Zhu, Q1
Wu, M1
Gonzalez-Nafria, N1
Rojo-Lopez, A1
Martinez-Velasco, E1
Gonzalez-Gonzalez, D1
de la Fuente-Bobillo, MA1
Tola-Arribas, MA1
Ortega-Valin, F1
Azuma, N1
Ohta, M1
Kageyama, Y1
Kawanaka, Y1
Matsui, K1
Higashi, M1
Irioka, T1
Matsumoto, T1
Mizusawa, H1
Naqi, R1
Azeemuddin, M1
Beg, MA1
Chakrabarti, S1
Pan, K1
Hobbs, K1
Stern-Nezer, S1
Buckwalter, MS1
Fischbein, N1
Finley Caulfield, A1
Godfrey, MS1
Finn, A1
Zainah, H1
Dapaah-Afriyie, K1
Furukawa, S1
Yamamoto, T1
Sugiyama, A1
Ohira, K1
Aotsuka, Y1
Koide, K1
Kojima, K1
Kuwabara, S1
Yokoyama, Y1
Asaoka, K1
Sugiyama, T1
Uchida, K1
Shimbo, D1
Kobayashi, S1
Itamoto, K1
Sandip, S1
Afshan, I1
Khandelwal, RK1
Kato, H1
Sosa, H1
Mori, M1
Kaneko, T1
Haridas, A1
Trivedi, TH1
Moulick, ND1
Joshi, AR1
Bhattacharyya, S1
Darby, RR1
Raibagkar, P1
Gonzalez Castro, LN1
Berkowitz, AL1
Farmakiotis, D1
Zeluff, B1
Bae, EH1
Ma, SK1
Kim, SK1
Kim, SW1
Dhar, A1
Manoila, I1
Dugay, MH1
Sellal, F1
Agah, E1
Habibi, A1
Naderi, H1
Tafakhori, A1
Boot, EM1
Hanny, KH1
Meijer, FJ1
van Eijk, JJ1
Galvez, M1
Brahm, J1
Miranda, M1
Groothoff, MV1
Hofmeijer, J1
Sikma, MA1
Meulenbelt, J1
Bottenberg, MM1
Hegge, KA1
Eastman, DK1
Kumar, R1
Cazals, X1
Omoumi, P1
Agnard, P1
Bibi, R1
Ferquel, C1
Cazeneuve, N1
Hocqueloux, L1
Magni, C1
Olwoch, IP1
Desai, JA1
Dobson, J1
Melanson, M1
Pari, G1
Jin, AY1
Cheong, HC1
Jeong, TG1
Cho, YB1
Yang, BJ1
Kim, TH1
Kim, HC1
Cho, EY1
Kim, SM1
Shin, HW1
Han, HJ1
Park, JH1
Papathanasiou, A1
Zouvelou, V1
Kyriazi, S1
Rentzos, M1
Evdokimidis, I1
Valla, F1
Berchiche, C1
Floret, D1
Seok, JI1
Yi, H1
Song, YM1
Lee, WY1
Kim, KH1
Choi, JW1
Lee, JY1
Kim, TD1
Paek, JH1
Lee, EJ1
Oh, HA1
Kim, JH2
Jang, BI1
Kim, TN1
Chung, MK1
Lee, HJ1
Byun, WM1
Hammami, N1
Drissi, C1
Sebai, R1
Araar, M1
Maatallah, Y1
Belghith, L1
Nagi, S1
Hentati, F1
Ben Hamouda, M1
Kim, E1
Na, DG1
Kim, EY1
Son, KR1
Chang, KH1
Bailes, J1
Willis, J1
Priebe, C1
Strub, R1
Alvarez, RS1
Richardson, DA1
Bent, AE1
Ostergard, DR1
Kusumi, RK1
Plouffe, JF1
Wyatt, RH1
Fass, RJ1
Ahmed, A1
Loes, DJ1
Bressler, EL1
Ostrosky-Wegman, P1
Gonsebatt, ME1
Arik, N1
Cengiz, N1
Bilge, A1
Sprott, MS1
Ingham, HR1
Jennings, FW1
Wienbren, M1
Perinpanayagam, RM1
Camba, L1
Lee, CA1
von Rogulja, P1
Kovac, W1
Schmid, H1

Reviews

6 reviews available for metronidazole and Brain Disorders

ArticleYear
[A case of irreversible metronidazole encephalopathy during liver abscess treatment].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2023, Volume: 120, Issue:10

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Brain Diseases; Female; Humans; Liver Abscess; Metronidazo

2023
Metronidazole-induced encephalopathy: a systematic review.
    Journal of neurology, 2020, Volume: 267, Issue:1

    Topics: Anti-Bacterial Agents; Brain Diseases; Humans; Metronidazole; Nervous System Diseases

2020
[Clinical Characteristics of Metronidazole-induced Encephalopathy: A Report of Two Cases and a Review of 32 Japanese Cases in the Literature].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 2015, Volume: 89, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Humans; Male; Metronidazole

2015
Antibiotic-associated encephalopathy.
    Neurology, 2016, Mar-08, Volume: 86, Issue:10

    Topics: Anti-Bacterial Agents; Brain Diseases; Cephalosporins; Female; Humans; Male; Metronidazole; Middle A

2016
Metronidazole-induced encephalopathy: a case report and review of the literature.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:1

    Topics: Anti-Infective Agents; Brain Diseases; Follow-Up Studies; Humans; Magnetic Resonance Imaging; Male;

2011
Metronidazole-induced encephalopathy: case report and review of MRI findings.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:3

    Topics: Aged; Anti-Infective Agents; Brain Diseases; Brain Edema; Diffusion Magnetic Resonance Imaging; Huma

2011

Other Studies

68 other studies available for metronidazole and Brain Disorders

ArticleYear
Metronidazole-induced encephalopathy: Symmetrical hyperintensity on imaging.
    Cleveland Clinic journal of medicine, 2021, Dec-02, Volume: 88, Issue:12

    Topics: Brain Diseases; Diagnostic Imaging; Diagnostic Tests, Routine; Humans; Magnetic Resonance Imaging; M

2021
Metronidazole Induced Cerebellar Toxicity: A Case Report.
    JNMA; journal of the Nepal Medical Association, 2021, Sep-11, Volume: 59, Issue:241

    Topics: Anti-Bacterial Agents; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Metronidazole; Neur

2021
Diffuse subcortical white matter restriction: An uncommon finding on metronidazole toxicity.
    The neuroradiology journal, 2023, Volume: 36, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Brain Diseases; Diffusion; Female; Humans; Metronidazole; White Matter

2023
Metronidazole-induced encephalopathy: Uncommon cause of recurrent falling in a geriatric man.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2023, Volume: 56, Issue:1

    Topics: Accidental Falls; Aged; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Metronidazole

2023
Management of a rare case of metronidazole-induced encephalopathy presenting as posterior reversible encephalopathy syndrome: a case report.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2023, Volume: 44, Issue:3

    Topics: Brain Diseases; Humans; Magnetic Resonance Imaging; Metronidazole; Posterior Leukoencephalopathy Syn

2023
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
    BMC neurology, 2022, Dec-15, Volume: 22, Issue:1

    Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic

2022
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
    BMC neurology, 2022, Dec-15, Volume: 22, Issue:1

    Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic

2022
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
    BMC neurology, 2022, Dec-15, Volume: 22, Issue:1

    Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic

2022
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
    BMC neurology, 2022, Dec-15, Volume: 22, Issue:1

    Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic

2022
Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report.
    Medicine, 2023, Feb-03, Volume: 102, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Brain Ischemia; Cerebellar Diseases; Delayed Diagnosis;

2023
[Metronidazole-induced encephalopathy: description of a case with radiological and anatomopathological findings].
    Revista de neurologia, 2019, 09-16, Volume: 69, Issue:6

    Topics: Anti-Infective Agents; Brain Diseases; Humans; Metronidazole; Radiography

2019
Case 271: Metronidazole-induced Encephalopathy.
    Radiology, 2019, Volume: 293, Issue:2

    Topics: Anti-Bacterial Agents; Brain; Brain Diseases; Child; Fusobacterium Infections; Humans; Magnetic Reso

2019
Persistent dystonia and basal ganglia involvement following metronidazole induced encephalopathy.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020, Volume: 41, Issue:4

    Topics: Basal Ganglia; Brain Diseases; Dystonia; Dystonic Disorders; Humans; Metronidazole

2020
Cortical Visual Impairment Treated by Plasmapheresis in a Child With Metronidazole-Induced Encephalopathy.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2021, 03-01, Volume: 41, Issue:1

    Topics: Adolescent; Anti-Bacterial Agents; Blindness, Cortical; Brain Diseases; Humans; Magnetic Resonance I

2021
Acute metronidazole-induced neurotoxicity: an update on MRI findings.
    Clinical radiology, 2020, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Brain Diseases; Child; Diffusion

2020
Metronidazole induced encephalopathy: case report and discussion on the differential diagnoses, in particular, Wernicke's encephalopathy.
    Journal of radiology case reports, 2019, Volume: 13, Issue:9

    Topics: Anti-Infective Agents; Brain Diseases; Diagnosis, Differential; Humans; Magnetic Resonance Imaging;

2019
Isolated involvement of corpus callosum in metronidazole-induced encephalopathy with concomitant peripheral neuropathy: A case report.
    Medicine, 2020, Volume: 99, Issue:20

    Topics: Adult; Aged; Antiprotozoal Agents; Brain Diseases; Corpus Callosum; Dysentery, Amebic; Humans; Magne

2020
Ataxia and Parkinsonism in Metronidazole Neurotoxicity.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2021, Volume: 48, Issue:2

    Topics: Ataxia; Brain Diseases; Cerebellar Ataxia; Humans; Magnetic Resonance Imaging; Metronidazole; Neurot

2021
A Case of Topical Metronidazole-Induced Encephalopathy.
    JAMA neurology, 2020, 10-01, Volume: 77, Issue:10

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Brain Diseases; Humans; Male; Metronidazole

2020
The pharmacokinetics of oral metronidazole in patients with metronidazole-induced encephalopathy undergoing maintenance hemodialysis.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2020, Volume: 24, Issue:4

    Topics: Administration, Oral; Aged; Brain Diseases; Female; Humans; Metronidazole; Renal Dialysis

2020
[Encefalopathy as a side effect of metronidazole therapy – a case report].
    Lakartidningen, 2017, 03-20, Volume: 114

    Topics: Abscess; Aged; Anti-Infective Agents; Ataxia; Brain Diseases; Dysarthria; Female; Gait Disorders, Ne

2017
Thiamine deficiency in metronidazole-induced encephalopathy: A metabolic correlation?
    Journal of the neurological sciences, 2017, 08-15, Volume: 379

    Topics: Aged; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Metronidazole; Neuroimaging; Thiamin

2017
[Metronidazole-induced encephalopathy (MIE)].
    Presse medicale (Paris, France : 1983), 2017, Volume: 46, Issue:12 Pt 1

    Topics: Aged, 80 and over; Anti-Infective Agents; Brain Diseases; Female; Humans; Liver Abscess; Magnetic Re

2017
Case Report of Metronidazole-Induced Encephalopathy.
    WMJ : official publication of the State Medical Society of Wisconsin, 2017, Volume: 116, Issue:5

    Topics: Aged, 80 and over; Anti-Infective Agents; Brain Diseases; Clostridium Infections; Colitis; Female; H

2017
Metronidazole-Associated Encephalopathy.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:2

    Topics: Administration, Intravenous; Aged, 80 and over; Anti-Bacterial Agents; Brain Diseases; Female; Fusob

2018
Metronidazole-induced encephalopathy.
    Revue neurologique, 2018, Volume: 174, Issue:5

    Topics: Aged; Antitrichomonal Agents; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Metronidazol

2018
Metronidazole-associated encephalopathy: a reversible condition.
    Internal and emergency medicine, 2018, Volume: 13, Issue:8

    Topics: Anti-Bacterial Agents; Ataxia; Brain Diseases; Confusion; Humans; Magnetic Resonance Imaging; Male;

2018
Convulsive seizures caused by metronidazole-induced encephalopathy.
    Postgraduate medical journal, 2019, Volume: 95, Issue:1122

    Topics: Abdominal Abscess; Anti-Infective Agents; Brain Diseases; Cerebellar Nuclei; Humans; Magnetic Resona

2019
Metronidazole-induced encephalopathy during treatment for refractory diarrhea after cord blood transplantation.
    Clinical journal of gastroenterology, 2019, Volume: 12, Issue:5

    Topics: Anti-Bacterial Agents; Brain; Brain Diseases; Colonoscopy; Cord Blood Stem Cell Transplantation; Dia

2019
Defining metronidazole-induced encephalopathy.
    Journal of neurology, 2019, Volume: 266, Issue:5

    Topics: Brain Diseases; Humans; Magnetic Resonance Imaging; Metronidazole

2019
A case of methylprednisolone treatment for metronidazole-induced encephalopathy.
    BMC neurology, 2019, Mar-30, Volume: 19, Issue:1

    Topics: Brain Diseases; Dysarthria; Gait Ataxia; Humans; Magnetic Resonance Imaging; Male; Methylprednisolon

2019
[Metronidazole-induced encephalopathy: description of a case with radiological and anatomopathological findings].
    Revista de neurologia, 2019, Jul-01, Volume: 69, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Metronidazo

2019
Delayed onset of metronidazole-induced encephalopathy in a patient with systemic sclerosis accompanied by intestinal pseudo-obstruction.
    Scandinavian journal of rheumatology, 2020, Volume: 49, Issue:1

    Topics: Anti-Bacterial Agents; Brain; Brain Diseases; Diagnosis, Differential; Female; Humans; Intestinal Ps

2020
Metronidazole-induced encephalopathy.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:7

    Topics: Aged; Brain Diseases; Female; Humans; Metronidazole

2013
Magnetic resonance imaging of metronidazole induced encephalopathy.
    JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:8

    Topics: Adult; Anti-Infective Agents; Brain; Brain Diseases; Diagnosis, Differential; Humans; Magnetic Reson

2012
Metronidazole-induced encephalopathy: an uncommon scenario.
    The New Zealand medical journal, 2014, May-02, Volume: 127, Issue:1393

    Topics: Adult; Anti-Infective Agents; Brain Diseases; Diagnosis, Differential; Diarrhea; Humans; Magnetic Re

2014
Metronidazole-induced encephalopathy: not always a reversible situation.
    Neurocritical care, 2015, Volume: 22, Issue:3

    Topics: Aged; Anti-Infective Agents; Brain Diseases; Fatal Outcome; Female; Humans; Metronidazole

2015
Metronidazole-induced encephalopathy after prolonged metronidazole course for treatment of C. difficile colitis.
    BMJ case reports, 2015, Jan-16, Volume: 2015

    Topics: Aged; Anti-Infective Agents; Brain Diseases; Clostridioides difficile; Enterocolitis, Pseudomembrano

2015
Metronidazole-induced encephalopathy with contrast enhancing lesions on MRI.
    Journal of the neurological sciences, 2015, May-15, Volume: 352, Issue:1-2

    Topics: Anti-Infective Agents; Brain Diseases; Humans; Magnetic Resonance Imaging; Male; Metronidazole; Midd

2015
Metronidazole: encephalopathy.
    Prescrire international, 2015, Volume: 24, Issue:158

    Topics: Brain Diseases; Humans; Metronidazole

2015
[Metronidazole-Induced Encephalopathy during Brain Abscess Treatment:Two Case Reports].
    No shinkei geka. Neurological surgery, 2015, Volume: 43, Issue:10

    Topics: Brain Abscess; Brain Diseases; Diffusion Magnetic Resonance Imaging; Female; Humans; Male; Metronida

2015
MR features of metronidazole-induced encephalopathy.
    BMJ case reports, 2015, Oct-05, Volume: 2015

    Topics: Anti-Infective Agents; Brain; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Metronidaz

2015
Metronidazole-Induced Encephalopathy in Chronic Diarrhoea.
    The Journal of the Association of Physicians of India, 2015, Volume: 63, Issue:6

    Topics: Anti-Infective Agents; Brain Diseases; Chronic Disease; Diarrhea; Female; Humans; Metronidazole; Mid

2015
IMAGES IN CLINICAL MEDICINE. Metronidazole-Associated Encephalopathy.
    The New England journal of medicine, 2016, Apr-14, Volume: 374, Issue:15

    Topics: Bacteremia; Brain Diseases; Catheterization, Central Venous; Clostridium Infections; Dysarthria; Fat

2016
Metronidazole-Induced Encephalopathy: A Case Report.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2016, Volume: 83, Issue:2

    Topics: Aged; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Metronidazole

2016
Mystery Case: Metronidazole-induced encephalopathy.
    Neurology, 2016, 08-30, Volume: 87, Issue:9

    Topics: Aged, 80 and over; Anti-Infective Agents; Brain Diseases; Female; Humans; Metronidazole

2016
Chestnut Sign: Metronidazole-Induced Encephalopathy.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:1

    Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Ataxia; Brain Diseases; Ciprofloxacin; Depression; D

2017
Metronidazole-induced neurotoxicity presenting with sudden bilateral hearing loss, encephalopathy, and cerebellar dysfunction.
    European journal of clinical pharmacology, 2017, Volume: 73, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Brain Diseases; Female; Hearing Loss, Bilateral; Helicobacter Infectio

2017
[A woman with reversible encephalopathy].
    Nederlands tijdschrift voor geneeskunde, 2017, Volume: 161

    Topics: Aged; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Metronidazole

2017
Movement disorders as a manifestation of metronidazole-induced encephalopathy in a patient with chronic liver disease.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Sep-15, Volume: 24, Issue:12

    Topics: Anti-Infective Agents; Brain Diseases; Chronic Disease; Diffusion Magnetic Resonance Imaging; Humans

2009
Irreversible encephalopathy after treatment with high-dose intravenous metronidazole.
    Clinical therapeutics, 2010, Volume: 32, Issue:1

    Topics: Adult; Anti-Infective Agents; Brain Diseases; Diagnosis, Differential; Dose-Response Relationship, D

2010
[Reversible metronidazole-induced encephalopathy and hypertrophic olivary degeneration].
    Journal de radiologie, 2010, Volume: 91, Issue:3 Pt 1

    Topics: Anti-Infective Agents; Brain Abscess; Brain Diseases; Follow-Up Studies; Fusobacterium Infections; F

2010
Microbiology of acute complicated bacterial sinusitis at the University of the Witwatersrand.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2010, Jul-26, Volume: 100, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Bacterial Infections; Brain Diseases; Child; Drug Resistance, Bact

2010
Metronidazole-induced encephalopathy in a patient with liver cirrhosis.
    The Korean journal of hepatology, 2011, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Brain Diseases; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Magnetic Res

2011
Serially changing metronidazole-induced encephalopathy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2011, Volume: 38, Issue:6

    Topics: Anti-Infective Agents; Brain Diseases; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Follow

2011
Metronidazole-induced reversible encephalopathy in a patient with facioscapulohumeral muscular dystrophy.
    Clinical neuroradiology, 2013, Volume: 23, Issue:3

    Topics: Anti-Bacterial Agents; Brain Diseases; Diagnosis, Differential; Humans; Male; Metronidazole; Middle

2013
[Necrobacillosis and Lemierre's syndrome: case report].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2003, Volume: 10, Issue:12

    Topics: Amoxicillin; Anti-Infective Agents; Brain Diseases; Child, Preschool; Female; Fusobacterium Infectio

2003
Metronidazole-induced encephalopathy and inferior olivary hypertrophy: lesion analysis with diffusion-weighted imaging and apparent diffusion coefficient maps.
    Archives of neurology, 2003, Volume: 60, Issue:12

    Topics: Aged; Brain; Brain Diseases; Diffusion Magnetic Resonance Imaging; Drug Administration Schedule; Fem

2003
[Two cases of metronidazole-induced encephalopathy].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2005, Volume: 45, Issue:3

    Topics: Anti-Infective Agents; Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Magnetic Resonanc

2005
Reversible metronidazole-induced encephalopathy.
    Journal of neuroradiology = Journal de neuroradiologie, 2007, Volume: 34, Issue:2

    Topics: Anti-Infective Agents; Brain Diseases; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance I

2007
MR imaging of metronidazole-induced encephalopathy: lesion distribution and diffusion-weighted imaging findings.
    AJNR. American journal of neuroradiology, 2007, Volume: 28, Issue:9

    Topics: Aged; Anti-Infective Agents; Brain; Brain Diseases; Diffusion Magnetic Resonance Imaging; Female; Hu

2007
Encephalopathy with metronidazole in a child.
    American journal of diseases of children (1960), 1983, Volume: 137, Issue:3

    Topics: Brain Diseases; Child; Coma; Humans; Male; Metronidazole; Seizures

1983
Central nervous system toxicity related to prolonged metronidazole therapy.
    American journal of obstetrics and gynecology, 1983, Mar-01, Volume: 145, Issue:5

    Topics: Abscess; Adult; Bacteroides fragilis; Bacteroides Infections; Brain Diseases; Female; Humans; Metron

1983
Central nervous system toxicity associated with metronidazole therapy.
    Annals of internal medicine, 1980, Volume: 93, Issue:1

    Topics: Blood-Brain Barrier; Brain Diseases; Cerebellar Ataxia; Female; Humans; Metronidazole; Middle Aged;

1980
Reversible magnetic resonance imaging findings in metronidazole-induced encephalopathy.
    Neurology, 1995, Volume: 45, Issue:3 Pt 1

    Topics: Brain Diseases; Female; Humans; Magnetic Resonance Imaging; Metronidazole; Middle Aged

1995
Environmental toxicants in developing countries.
    Environmental health perspectives, 1996, Volume: 104 Suppl 3

    Topics: Animal Population Groups; Animals; Antiparasitic Agents; Brain Diseases; Carcinogens; Chromosome Abe

1996
Metronidazole-induced encephalopathy in a uremic patient: a case report.
    Nephron, 2001, Volume: 89, Issue:1

    Topics: Anti-Infective Agents; Brain Diseases; Female; Humans; Kidney Failure, Chronic; Metronidazole; Middl

2001
Treatment of infections due to nonsporing anaerobes.
    Drugs, 1979, Volume: 18, Issue:2

    Topics: Anaerobiosis; Anti-Bacterial Agents; Bacterial Infections; Brain Diseases; Cefoxitin; Clindamycin; G

1979
Chemotherapy of CNS-trypanosomiasis: the combined use of the arsenicals and nitro-compounds.
    Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1991, Volume: 42, Issue:2

    Topics: Animals; Antiprotozoal Agents; Arsenicals; Brain Diseases; Drug Synergism; Drug Therapy, Combination

1991
Convulsions and encephalopathy in a patient with leukemia after treatment with metronidazole.
    Journal of clinical pathology, 1985, Volume: 38, Issue:9

    Topics: Adult; Brain Diseases; Epilepsy; Female; Humans; Leukemia, Myeloid, Acute; Metronidazole

1985
[Metronidazol encephalopathy in rats].
    Acta neuropathologica, 1973, Jun-26, Volume: 25, Issue:1

    Topics: Animals; Brain Diseases; Brain Stem; Cerebellum; Female; Inferior Colliculi; Metronidazole; Rats; Th

1973