metronidazole has been researched along with Bovine Diseases in 14 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Excerpt | Relevance | Reference |
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" Thus, the aim of this study was to verify whether Se and vitamins (A and E) applied via subcutaneous associated with secnidazole via oral exert positive effects in the antioxidant and immune systems, as well as whether prevent infections caused by protozoan and bacteria, and consequently, reduce the number of cases of diarrhea in heifers." | 5.27 | A prophylactic protocol to stimulate the immune response also controls infectious disease and, consequently, minimizes diarrhea in newborn heifers. ( Baldissera, MD; Bottari, NB; Crecencio, RB; Da Silva, AS; Fortuoso, BF; Machado, G; Morsch, VMM; Pereira, WAB; Ribeiro, MP; Schetinger, MRC; Secco, R; Stefani, LM; Tomasi, T; Volpato, A, 2018) |
"The high Giardia infection rates and intensities in calves of a wide age range and the clinical response to metronidazole suggest that Giardia infection contributed to the outbreaks of diarrhea." | 1.29 | Concurrent infections of Giardia and Cryptosporidium on two Ohio farms with calf diarrhea. ( Herd, RP; Rings, DM; Xiao, L, 1993) |
"Radiography revealed septic arthritis of the distal interphalangeal joint and osteomyelitis of the distal and middle phalanges." | 1.29 | Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull. ( Hendrickson, DA; Klohnen, AA; Stone, WC; Trostle, SS, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (28.57) | 18.7374 |
1990's | 5 (35.71) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (35.71) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Love, D | 1 |
Fajt, VR | 1 |
Hairgrove, T | 1 |
Jones, M | 1 |
Thompson, JA | 1 |
Volpato, A | 2 |
Fortuoso, BF | 2 |
Campigotto, G | 1 |
Glombowsky, P | 1 |
Bottari, NB | 2 |
Lopes, LS | 1 |
Da Silva, AS | 2 |
Crecencio, RB | 1 |
Tomasi, T | 1 |
Ribeiro, MP | 1 |
Secco, R | 1 |
Pereira, WAB | 1 |
Schetinger, MRC | 1 |
Morsch, VMM | 1 |
Baldissera, MD | 1 |
Stefani, LM | 1 |
Machado, G | 1 |
Rivero, MB | 1 |
Luque, ME | 1 |
Abdala, ME | 1 |
Luna, BE | 1 |
Di Lullo, D | 1 |
Echaide, IE | 1 |
Carranza, PG | 1 |
Rivero, FD | 1 |
Zalonis, CA | 1 |
Pillay, A | 1 |
Secor, W | 1 |
Humburg, B | 1 |
Aber, R | 1 |
Xiao, L | 1 |
Herd, RP | 1 |
Rings, DM | 1 |
Trostle, SS | 1 |
Hendrickson, DA | 1 |
Stone, WC | 1 |
Klohnen, AA | 1 |
Cohen, RO | 1 |
Colodner, R | 1 |
Ziv, G | 1 |
Keness, J | 1 |
Yeruham, I | 1 |
Perl, S | 1 |
van den Bogaard, AE | 1 |
Hazen, MJ | 1 |
Kriele, CP | 1 |
Stephens, LR | 1 |
Slee, KJ | 1 |
Brodrick, TW | 1 |
Reshetniak, VZ | 1 |
Bartenev, VS | 1 |
Bibikov, FA | 1 |
Pakhomova, NG | 1 |
Golikov, AV | 1 |
Khodorovskiĭ, A | 1 |
Zablotskiĭ, V | 1 |
Timchenko, K | 1 |
Ol'khovik, V | 1 |
Iamkovoĭ, A | 1 |
1 trial available for metronidazole and Bovine Diseases
Article | Year |
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A prophylactic protocol to stimulate the immune response also controls infectious disease and, consequently, minimizes diarrhea in newborn heifers.
Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Cattle; Cattle Diseases; Cholesterol; Diarrh | 2018 |
13 other studies available for metronidazole and Bovine Diseases
Article | Year |
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Metronidazole for the treatment of Tritrichomonas foetus in bulls.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Male; Metronidazole; Protozoan Infections, A | 2017 |
Secnidazole for control of giardiasis in dairy calves.
Topics: Animals; Animals, Newborn; Antiprotozoal Agents; Cattle; Cattle Diseases; Feces; Female; Giardia lam | 2018 |
In Vitro Susceptibility to Metronidazole of Tritrichomonas foetus Bovine Isolates from Argentina.
Topics: Aerobiosis; Anaerobiosis; Animals; Antiprotozoal Agents; Argentina; Cattle; Cattle Diseases; Metroni | 2019 |
Rare case of trichomonal peritonitis.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Common Variable Immunodeficiency; DNA Finger | 2011 |
Concurrent infections of Giardia and Cryptosporidium on two Ohio farms with calf diarrhea.
Topics: Animals; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Outbreaks; F | 1993 |
Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull.
Topics: Actinomyces; Actinomycosis; Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Inflammatory | 1996 |
Isolation and antimicrobial susceptibility of obligate anaerobic bacteria recovered from the uteri of dairy cows with retained fetal membranes and postparturient endometritis.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Cattle; Cattle Diseases; Ciprofloxacin; Clindam | 1996 |
Clinical aspects of an outbreak of papillomatous digital dermatitis in a dairy cattle herd.
Topics: Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Dairying; Disease Outbreaks; Drug Therapy, | 1998 |
Rationale for treatment of retained placenta in cows with neomycin and metronidazole.
Topics: Animals; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Cattle; Cattle Diseases; Drug | 1992 |
Metronidazole for the treatment of bovine pyometra.
Topics: Ampicillin; Animals; Bacterial Infections; Cattle; Cattle Diseases; Drug Therapy, Combination; Endom | 1987 |
Internal navel abscesses.
Topics: Abscess; Animals; Cattle; Cattle Diseases; Drug Therapy, Combination; Metronidazole; Umbilicus | 1986 |
[Metronidazole (Trikhopol)--an effective drug for trichomoniasis in cattle].
Topics: Animals; Cattle; Cattle Diseases; Female; Male; Metronidazole; Trichomonas Infections; Trichomonas V | 1969 |
[Study of the efficacy of metronidazole in trichomoniasis].
Topics: Animals; Cattle; Cattle Diseases; Male; Metronidazole; Trichomonas Infections | 1970 |