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metronidazole and Bovine Diseases

metronidazole has been researched along with Bovine Diseases in 14 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
" Thus, the aim of this study was to verify whether Se and vitamins (A and E) applied via subcutaneous associated with secnidazole via oral exert positive effects in the antioxidant and immune systems, as well as whether prevent infections caused by protozoan and bacteria, and consequently, reduce the number of cases of diarrhea in heifers."5.27A prophylactic protocol to stimulate the immune response also controls infectious disease and, consequently, minimizes diarrhea in newborn heifers. ( Baldissera, MD; Bottari, NB; Crecencio, RB; Da Silva, AS; Fortuoso, BF; Machado, G; Morsch, VMM; Pereira, WAB; Ribeiro, MP; Schetinger, MRC; Secco, R; Stefani, LM; Tomasi, T; Volpato, A, 2018)
"The high Giardia infection rates and intensities in calves of a wide age range and the clinical response to metronidazole suggest that Giardia infection contributed to the outbreaks of diarrhea."1.29Concurrent infections of Giardia and Cryptosporidium on two Ohio farms with calf diarrhea. ( Herd, RP; Rings, DM; Xiao, L, 1993)
"Radiography revealed septic arthritis of the distal interphalangeal joint and osteomyelitis of the distal and middle phalanges."1.29Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull. ( Hendrickson, DA; Klohnen, AA; Stone, WC; Trostle, SS, 1996)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's5 (35.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Love, D1
Fajt, VR1
Hairgrove, T1
Jones, M1
Thompson, JA1
Volpato, A2
Fortuoso, BF2
Campigotto, G1
Glombowsky, P1
Bottari, NB2
Lopes, LS1
Da Silva, AS2
Crecencio, RB1
Tomasi, T1
Ribeiro, MP1
Secco, R1
Pereira, WAB1
Schetinger, MRC1
Morsch, VMM1
Baldissera, MD1
Stefani, LM1
Machado, G1
Rivero, MB1
Luque, ME1
Abdala, ME1
Luna, BE1
Di Lullo, D1
Echaide, IE1
Carranza, PG1
Rivero, FD1
Zalonis, CA1
Pillay, A1
Secor, W1
Humburg, B1
Aber, R1
Xiao, L1
Herd, RP1
Rings, DM1
Trostle, SS1
Hendrickson, DA1
Stone, WC1
Klohnen, AA1
Cohen, RO1
Colodner, R1
Ziv, G1
Keness, J1
Yeruham, I1
Perl, S1
van den Bogaard, AE1
Hazen, MJ1
Kriele, CP1
Stephens, LR1
Slee, KJ1
Brodrick, TW1
Reshetniak, VZ1
Bartenev, VS1
Bibikov, FA1
Pakhomova, NG1
Golikov, AV1
Khodorovskiĭ, A1
Zablotskiĭ, V1
Timchenko, K1
Ol'khovik, V1
Iamkovoĭ, A1

Trials

1 trial available for metronidazole and Bovine Diseases

ArticleYear
A prophylactic protocol to stimulate the immune response also controls infectious disease and, consequently, minimizes diarrhea in newborn heifers.
    Microbial pathogenesis, 2018, Volume: 121

    Topics: Animals; Animals, Newborn; Antioxidants; Blood Glucose; Cattle; Cattle Diseases; Cholesterol; Diarrh

2018

Other Studies

13 other studies available for metronidazole and Bovine Diseases

ArticleYear
Metronidazole for the treatment of Tritrichomonas foetus in bulls.
    BMC veterinary research, 2017, Apr-14, Volume: 13, Issue:1

    Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Male; Metronidazole; Protozoan Infections, A

2017
Secnidazole for control of giardiasis in dairy calves.
    Experimental parasitology, 2018, Volume: 189

    Topics: Animals; Animals, Newborn; Antiprotozoal Agents; Cattle; Cattle Diseases; Feces; Female; Giardia lam

2018
In Vitro Susceptibility to Metronidazole of Tritrichomonas foetus Bovine Isolates from Argentina.
    Acta parasitologica, 2019, Volume: 64, Issue:2

    Topics: Aerobiosis; Anaerobiosis; Animals; Antiprotozoal Agents; Argentina; Cattle; Cattle Diseases; Metroni

2019
Rare case of trichomonal peritonitis.
    Emerging infectious diseases, 2011, Volume: 17, Issue:7

    Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Common Variable Immunodeficiency; DNA Finger

2011
Concurrent infections of Giardia and Cryptosporidium on two Ohio farms with calf diarrhea.
    Veterinary parasitology, 1993, Volume: 51, Issue:1-2

    Topics: Animals; Cattle; Cattle Diseases; Cryptosporidiosis; Cryptosporidium; Diarrhea; Disease Outbreaks; F

1993
Use of antimicrobial-impregnated polymethyl methacrylate beads for treatment of chronic, refractory septic arthritis and osteomyelitis of the digit in a bull.
    Journal of the American Veterinary Medical Association, 1996, Feb-01, Volume: 208, Issue:3

    Topics: Actinomyces; Actinomycosis; Administration, Oral; Animals; Anti-Bacterial Agents; Anti-Inflammatory

1996
Isolation and antimicrobial susceptibility of obligate anaerobic bacteria recovered from the uteri of dairy cows with retained fetal membranes and postparturient endometritis.
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1996, Volume: 43, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Cattle; Cattle Diseases; Ciprofloxacin; Clindam

1996
Clinical aspects of an outbreak of papillomatous digital dermatitis in a dairy cattle herd.
    Journal of the South African Veterinary Association, 1998, Volume: 69, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Dairying; Disease Outbreaks; Drug Therapy,

1998
Rationale for treatment of retained placenta in cows with neomycin and metronidazole.
    The Veterinary record, 1992, Apr-18, Volume: 130, Issue:16

    Topics: Animals; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Cattle; Cattle Diseases; Drug

1992
Metronidazole for the treatment of bovine pyometra.
    Australian veterinary journal, 1987, Volume: 64, Issue:11

    Topics: Ampicillin; Animals; Bacterial Infections; Cattle; Cattle Diseases; Drug Therapy, Combination; Endom

1987
Internal navel abscesses.
    The Veterinary record, 1986, May-31, Volume: 118, Issue:22

    Topics: Abscess; Animals; Cattle; Cattle Diseases; Drug Therapy, Combination; Metronidazole; Umbilicus

1986
[Metronidazole (Trikhopol)--an effective drug for trichomoniasis in cattle].
    Veterinariia, 1969, Volume: 46, Issue:3

    Topics: Animals; Cattle; Cattle Diseases; Female; Male; Metronidazole; Trichomonas Infections; Trichomonas V

1969
[Study of the efficacy of metronidazole in trichomoniasis].
    Veterinariia, 1970, Volume: 10

    Topics: Animals; Cattle; Cattle Diseases; Male; Metronidazole; Trichomonas Infections

1970