metronidazole has been researched along with Biliary Tract Diseases in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Biliary Tract Diseases: Diseases in any part of the BILIARY TRACT including the BILE DUCTS and the GALLBLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Biliary ascariasis is one of the most common and well described entities caused by ascaris." | 1.33 | Management of biliary ascariasis in pregnancy. ( Javid, G; Khan, F; Robanni, I; Shah, OJ; Zargar, SA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shah, OJ | 1 |
| Robanni, I | 1 |
| Khan, F | 1 |
| Zargar, SA | 1 |
| Javid, G | 1 |
| Patel, S | 1 |
| Tuite, CM | 1 |
| Mondschein, JI | 1 |
| Soulen, MC | 1 |
| Kocherovets, VI | 1 |
| Stolbovoĭ, AV | 1 |
| Dzhalashev, IaKh | 1 |
| Nielsen, ML | 1 |
| Justesen, T | 1 |
| Spech, HJ | 1 |
| Cann, KJ | 1 |
| Watkins, RM | 1 |
| George, C | 1 |
| Payne-James, J | 1 |
| Crawfurd, E | 1 |
| Rogers, TR | 1 |
| Jensen, LS | 1 |
| Andersen, F | 1 |
| Gjøde, P | 1 |
| Kiil, J | 1 |
| Kløve-Mogensen, M | 1 |
| Lauritzen, NP | 1 |
| Nielsen, L | 1 |
| Skovgaard, S | 1 |
| Siniavskaia, OA | 1 |
| Toropova, NP | 1 |
| Gradinarov, AM | 1 |
1 review available for metronidazole and Biliary Tract Diseases
| Article | Year |
|---|---|
[Non-clostridial anaerobic infection in diseases of the liver and biliary tract (review of the Soviet and foreign literature)].
Topics: Age Factors; Aged; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Biliary Tract D | 1984 |
2 trials available for metronidazole and Biliary Tract Diseases
| Article | Year |
|---|---|
A trial of mezlocillin versus cefuroxime with or without metronidazole for the prevention of wound sepsis after biliary and gastrointestinal surgery.
Topics: Biliary Tract Diseases; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combinat | 1988 |
Peroperative cefuroxime v. long-term ampicillin and metronidazole in high-risk biliary and gastric surgery. A multicentre trial.
Topics: Adult; Aged; Ampicillin; Biliary Tract Diseases; Cefuroxime; Cephalosporins; Clinical Trials as Topi | 1987 |
5 other studies available for metronidazole and Biliary Tract Diseases
| Article | Year |
|---|---|
Management of biliary ascariasis in pregnancy.
Topics: Adult; Ampicillin; Anti-Infective Agents; Ascariasis; Biliary Tract Diseases; Cholangiopancreatograp | 2005 |
Effectiveness of an aggressive antibiotic regimen for chemoembolization in patients with previous biliary intervention.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Biliary Tract Diseases; Case-Control Studies; Chemoem | 2006 |
Excretion of metroindazole in human bile. Investigations of hepatic bile, common duct bile, and gallbladder bile.
Topics: Administration, Oral; Adult; Aged; Bile; Biliary Tract Diseases; Biological Assay; Common Bile Duct; | 1977 |
[Lambliasis. Profile of a diarrheic disease].
Topics: Biliary Tract Diseases; Diarrhea; Disease Outbreaks; Giardia; Giardiasis; Humans; Metronidazole; Nim | 1978 |
[Value of sanation of the biliary tract in the complex pathogenetic therapy of allergic dermatitis in children].
Topics: Adolescent; Amino Acids; Antiprotozoal Agents; Ascorbic Acid; Biliary Tract Diseases; Child; Child, | 1974 |