metronidazole has been researched along with Besnoitiasis in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with metronidazole induced the disappearance of coccidia from the stool and clinical remission." | 1.26 | Malabsorption syndrome, coccidiosis, combined immune deficiency, and fulminant lymphoproliferative disease. ( Adar, U; Hallak, A; Ratan, Y; Yust, I, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, Y | 1 |
| Liu, X | 1 |
| Zhang, S | 1 |
| Tang, X | 1 |
| Zou, J | 1 |
| Suo, X | 1 |
| Wolfe, MS | 1 |
| Hallak, A | 1 |
| Yust, I | 1 |
| Ratan, Y | 1 |
| Adar, U | 1 |
| Taylor, AP | 1 |
| Davis, LJ | 1 |
| Soave, R | 1 |
| Apted, FI | 1 |
| Knight, R | 1 |
| Schultz, MG | 1 |
| Hoskins, DW | 1 |
| Marsden, PD | 1 |
| Trier, JS | 1 |
| Moxey, PC | 1 |
| Schimmel, EM | 1 |
| Robles, E | 1 |
| Reshetniak, VZ | 1 |
| Bartenev, VS | 1 |
| Rubanov, AA | 1 |
4 reviews available for metronidazole and Besnoitiasis
| Article | Year |
|---|---|
The treatment of intestinal protozoan infections.
Topics: Amebicides; Antimalarials; Antiprotozoal Agents; Balantidiasis; Chloroquine; Coccidiosis; Dientamoeb | 1982 |
Cyclospora.
Topics: Animals; Anti-Infective Agents; Antitrichomonal Agents; Ciprofloxacin; Coccidiosis; Eucoccidiida; Ga | 1997 |
Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.
Topics: Amebiasis; Animals; Balantidiasis; Coccidiosis; Emetine; Entamoeba; Entamoeba histolytica; Giardiasi | 1971 |
Intestinal parasites.
Topics: Animals; Anthelmintics; Antimony; Chloroquine; Coccidiosis; Diphyllobothriasis; Dysentery, Amebic; E | 1973 |
4 other studies available for metronidazole and Besnoitiasis
| Article | Year |
|---|---|
Antibiotic Changes Host Susceptibility to Eimeria falciformis Infection Associated with Alteration of Gut Microbiota.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Coccidiosis; Eimeria; Gastrointestinal Microbiome; Metro | 2022 |
Malabsorption syndrome, coccidiosis, combined immune deficiency, and fulminant lymphoproliferative disease.
Topics: Adult; Coccidiosis; Humans; Immunologic Deficiency Syndromes; Lymphoma; Malabsorption Syndromes; Mal | 1982 |
Chronic intestinal coccidiosis in man: intestinal morphology and response to treatment.
Topics: Antiprotozoal Agents; Biopsy; Chloroquine; Chronic Disease; Coccidiosis; Diagnosis, Differential; Di | 1974 |
[Trichopol--an effective drug in coccidiosis in rabbits].
Topics: Animals; Coccidiosis; Metronidazole; Rabbits | 1970 |