metronidazole has been researched along with Beriberi, Cerebral in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonalcoholic Wernicke's encephalopathy may share a similar metabolic pathway with MIE, resulting in difficulties in diagnosis." | 2.48 | Metronidazole-induced Encephalopathy: Case Report and Review Literature. ( Chen, LA; Cheng, SJ; Huang, YT, 2012) |
| "Metronidazole induced encephalopathy is a rare central nervous system toxicity, which may be completely reversible with prompt cessation of metronidazole usage." | 1.51 | Metronidazole induced encephalopathy: case report and discussion on the differential diagnoses, in particular, Wernicke's encephalopathy. ( Goh, CK; Hou, W; Yiin, RSZ, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miki, Y | 2 |
| Takeuchi, Y | 2 |
| Murasawa, S | 2 |
| Takayasu, S | 2 |
| Tsushima, F | 2 |
| Kakeda, S | 2 |
| Mizukami, H | 2 |
| Wakabayashi, K | 2 |
| Hou, W | 1 |
| Yiin, RSZ | 1 |
| Goh, CK | 1 |
| Mach, JC | 1 |
| Russell, J | 1 |
| Yui, JC | 1 |
| Bonnes, SL | 1 |
| Zuccoli, G | 1 |
| Pipitone, N | 1 |
| Santa Cruz, D | 1 |
| Huang, YT | 1 |
| Chen, LA | 1 |
| Cheng, SJ | 1 |
| Kim, DW | 1 |
| Park, JM | 1 |
| Yoon, BW | 1 |
| Baek, MJ | 1 |
| Kim, JE | 1 |
| Kim, S | 1 |
| von Rogulja, P | 1 |
| Kovac, W | 1 |
| Schmid, H | 1 |
1 review available for metronidazole and Beriberi, Cerebral
| Article | Year |
|---|---|
Metronidazole-induced Encephalopathy: Case Report and Review Literature.
Topics: Aged; Female; Humans; Magnetic Resonance Imaging; Mesencephalon; Metronidazole; Middle Aged; Radiati | 2012 |
7 other studies available for metronidazole and Beriberi, Cerebral
| Article | Year |
|---|---|
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report.
Topics: Autopsy; Brain Diseases; Diffusion Magnetic Resonance Imaging; Dysarthria; Female; Humans; Magnetic | 2022 |
Metronidazole induced encephalopathy: case report and discussion on the differential diagnoses, in particular, Wernicke's encephalopathy.
Topics: Anti-Infective Agents; Brain Diseases; Diagnosis, Differential; Humans; Magnetic Resonance Imaging; | 2019 |
A combined case of wernicke and metronidazole induced encephalopathy? Overlapping pathophysiologic pathways and MR imaging features.
Topics: Aged; Anti-Infective Agents; Brain; Humans; Magnetic Resonance Imaging; Male; Metronidazole; Neuroto | 2020 |
74-Year-Old Woman With Dysarthria and Left Lower Extremity Weakness.
Topics: Aged; Anti-Infective Agents; Dysarthria; Female; Humans; Lower Extremity; Metronidazole; Muscle Weak | 2017 |
Metronidazole-induced and Wernicke encephalopathy: two different entities sharing the same metabolic pathway?
Topics: Anti-Infective Agents; Brain; Cerebellar Nuclei; Dominance, Cerebral; Gastrointestinal Diseases; Hum | 2008 |
Metronidazole-induced encephalopathy.
Topics: Adult; Anti-Infective Agents; Attention; Brain Mapping; Diffusion Magnetic Resonance Imaging; Humans | 2004 |
[Metronidazol encephalopathy in rats].
Topics: Animals; Brain Diseases; Brain Stem; Cerebellum; Female; Inferior Colliculi; Metronidazole; Rats; Th | 1973 |