metronidazole has been researched along with Bacteroidaceae Infections in 38 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Bacteroidaceae Infections: Infections with bacteria of the family BACTEROIDACEAE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-two adult periodontitis patients were treated by the tablets of tinidazole (TNZ), and 23 patients treated by metronidazole (MNZ) served as control group." | 9.08 | [The effect of tinidazole in the treatment of adult periodontitis]. ( Chen, L; Ni, K; Wang, R, 1996) |
| "The aim of the present study was to monitor the microbiological and clinical effects of renewed supra- and subgingival debridement in conjunction with systemic metronidazole therapy (500 mg TID for 7 days) in 27 "refractory" periodontitis patients, culture positive for Bacteroides forsythus and negative for Actinobacillus actinomycetemcomitans." | 7.69 | Effects of metronidazole in patients with "refractory" periodontitis associated with Bacteroides forsythus. ( Timmerman, MF; Van der Velden, U; Van Winkelhoff, AJ; Vangsted, T; Winkel, EG, 1997) |
| "We report the first case of an infected breast cyst in a non-puerperal women due to this pathogen." | 5.46 | Infected breast cyst due to Prevotella buccae resistant to metronidazole. ( Cobo, F; Navarro-Marí, JM; Rodríguez-Granger, J; Sampedro, A, 2017) |
| "Patients with previously untreated chronic periodontitis and subgingival Actinobacillus actinomycetemcomitans and/or Porphyromonas gingivalis were randomly assigned to subgingival scaling without (control group) or with systemic amoxicillin plus metronidazole and CHX irrigation (test group)." | 5.11 | Adjunctive antimicrobial therapy of periodontitis: long-term effects on disease progression and oral colonization. ( Beikler, T; Ehmke, B; Flemmig, TF; Milian, E; Moter, A, 2005) |
| "Fifty-two adult periodontitis patients were treated by the tablets of tinidazole (TNZ), and 23 patients treated by metronidazole (MNZ) served as control group." | 5.08 | [The effect of tinidazole in the treatment of adult periodontitis]. ( Chen, L; Ni, K; Wang, R, 1996) |
| "The aim of the present study was to monitor the microbiological and clinical effects of renewed supra- and subgingival debridement in conjunction with systemic metronidazole therapy (500 mg TID for 7 days) in 27 "refractory" periodontitis patients, culture positive for Bacteroides forsythus and negative for Actinobacillus actinomycetemcomitans." | 3.69 | Effects of metronidazole in patients with "refractory" periodontitis associated with Bacteroides forsythus. ( Timmerman, MF; Van der Velden, U; Van Winkelhoff, AJ; Vangsted, T; Winkel, EG, 1997) |
| "We hereby, report a case of brain abscess in a 50-year-old man, who suffered a head trauma followed by decompression surgery 10 months ago." | 1.56 | Intracranial abscess due to Prevotella bivia: First case report from India. ( Biswas, R; Samantaray, S; Sasidharan, GM, 2020) |
| "Infection of a maternal urachal cyst during pregnancy is rare; Sonography is an important diagnostic tool that can help minimize maternal and fetal complications." | 1.48 | Sonographic detection of an infected maternal urachal cyst during pregnancy. ( Sargent, J; Sohaey, R; Trivedi, N, 2018) |
| "We report the first case of an infected breast cyst in a non-puerperal women due to this pathogen." | 1.46 | Infected breast cyst due to Prevotella buccae resistant to metronidazole. ( Cobo, F; Navarro-Marí, JM; Rodríguez-Granger, J; Sampedro, A, 2017) |
| "Forty-one periodontal abscess samples were cultivated on selective and non-selective culture media to isolate the oral anaerobes." | 1.40 | Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses. ( Chen, J; He, J; Miao, X; Wu, X; Xie, Y; Xu, B; Xu, M; Yu, L; Zhang, W, 2014) |
| "This approach could be used to treat recurrent periodontitis or other diseases caused by intracellular-dwelling organisms." | 1.39 | Polymersome-mediated intracellular delivery of antibiotics to treat Porphyromonas gingivalis-infected oral epithelial cells. ( Armes, SP; Battaglia, G; Douglas, CW; Lewis, AL; Murdoch, C; Pinnock, A; Thornhill, MH; Warren, NJ; Wayakanon, K, 2013) |
| "We report on a 16-month-old child with tetraplegia secondary to intramedullary abscesses because of a dermoid cyst infection associated with a dermal sinus." | 1.37 | Recovery after tetraplegia caused by dermal sinus infection: intramedullary abscess and tetraparesis. ( Brochard, S; Dam Hieu, P; Houx, L; Peudenier, S; Rémy-Néris, O, 2011) |
| "Metronidazole (MTZ) is a widely used antimicrobial agent." | 1.36 | Effect of metronidazole and modulation of cytokine production on human periodontal ligament cells. ( Annunziata, M; Bevilacqua, N; Guida, L; Paolillo, R; Rizzo, A; Tufano, MA, 2010) |
| "Metronidazole was also highly active against these strains: 316 of 320 Prevotella strains (98." | 1.35 | Activity of pradofloxacin against Porphyromonas and Prevotella spp. Implicated in periodontal disease in dogs: susceptibility test data from a European multicenter study. ( Greife, HA; Pridmore, A; Silley, P; Stephan, B, 2008) |
| "We are reporting the first case of septic arthritis due to Prevotella bivia in a patient with no pre-existing joint symptoms." | 1.35 | Septic arthritis of the knee joint secondary to Prevotella bivia. ( Baharoon, SA; Salman, SA, 2009) |
| "We report the first case of septic arthritis due to Prevotella bivia in a patient with severe, long-lasting rheumatoid arthritis (RA) treated with low doses of corticosteroids." | 1.31 | Septic arthiritis due to Prevotella bivia in a patient with rheumatoid arthritis. ( Alegre-Sancho, JJ; Juanola, X; Narvaez, FJ; Roig-Escofet, D, 2000) |
| "The first reported isolation from human noma lesions of F." | 1.30 | Isolation of Fusobacterium necrophorum from cancrum oris (noma). ( Enwonwu, CO; Falkler, WA; Idigbe, EO, 1999) |
| "To study the clinical manifestation and treatment of bacterial vaginosis (BV)." | 1.29 | [Clinical analysis of bacterial vaginosis in 76 cases]. ( Song, X; Weng, L; Yu, X, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 14 (36.84) | 29.6817 |
| 2010's | 14 (36.84) | 24.3611 |
| 2020's | 3 (7.89) | 2.80 |
| Authors | Studies |
|---|---|
| Stephan, B | 1 |
| Greife, HA | 1 |
| Pridmore, A | 1 |
| Silley, P | 1 |
| Alauzet, C | 2 |
| Mory, F | 2 |
| Teyssier, C | 1 |
| Hallage, H | 1 |
| Carlier, JP | 2 |
| Grollier, G | 1 |
| Lozniewski, A | 2 |
| Xie, M | 1 |
| Tang, Q | 1 |
| Nie, J | 1 |
| Zhang, C | 1 |
| Zhou, X | 1 |
| Yu, S | 1 |
| Sun, J | 1 |
| Cheng, X | 1 |
| Dong, N | 1 |
| Hu, Y | 1 |
| Chen, L | 2 |
| Happel, AU | 1 |
| Kullin, B | 1 |
| Gamieldien, H | 1 |
| Wentzel, N | 1 |
| Zauchenberger, CZ | 1 |
| Jaspan, HB | 1 |
| Dabee, S | 1 |
| Barnabas, SL | 1 |
| Jaumdally, SZ | 1 |
| Dietrich, J | 1 |
| Gray, G | 1 |
| Bekker, LG | 1 |
| Froissart, R | 1 |
| Passmore, JS | 1 |
| Samantaray, S | 1 |
| Biswas, R | 1 |
| Sasidharan, GM | 1 |
| Cobo, F | 1 |
| Rodríguez-Granger, J | 1 |
| Sampedro, A | 1 |
| Navarro-Marí, JM | 1 |
| Sargent, J | 1 |
| Sohaey, R | 1 |
| Trivedi, N | 1 |
| Aberkane, S | 1 |
| Pradel, B | 1 |
| Dumont, Y | 1 |
| Veloo, ACM | 3 |
| Laurens, C | 1 |
| Bonzon, L | 1 |
| Godreuil, S | 1 |
| Marchandin, H | 1 |
| Jean-Pierre, H | 2 |
| Ulger Toprak, N | 1 |
| Urban, E | 1 |
| Wybo, I | 1 |
| Justesen, US | 1 |
| Morris, T | 1 |
| Akgul, O | 1 |
| Kulekci, G | 1 |
| Soyletir, G | 1 |
| Nagy, E | 1 |
| Chlebowicz, M | 1 |
| Winter, HLJ | 1 |
| Bathoorn, D | 1 |
| Rossen, JWA | 1 |
| Xie, Y | 1 |
| Chen, J | 1 |
| He, J | 1 |
| Miao, X | 1 |
| Xu, M | 1 |
| Wu, X | 1 |
| Xu, B | 1 |
| Yu, L | 1 |
| Zhang, W | 1 |
| Wayakanon, K | 1 |
| Thornhill, MH | 1 |
| Douglas, CW | 1 |
| Lewis, AL | 1 |
| Warren, NJ | 1 |
| Pinnock, A | 1 |
| Armes, SP | 1 |
| Battaglia, G | 1 |
| Murdoch, C | 1 |
| Thomaidis, PC | 1 |
| Pantazatou, A | 1 |
| Kamariotis, S | 1 |
| Vlachos, K | 1 |
| Roussos, G | 1 |
| Panagiotou, P | 1 |
| Stylianakis, A | 1 |
| Amar, S | 1 |
| Wu, SC | 1 |
| Madan, M | 1 |
| Salman, SA | 1 |
| Baharoon, SA | 1 |
| Mittal, MK | 1 |
| Zimmerman, RA | 1 |
| van Winkelhoff, AJ | 3 |
| Winkel, EG | 3 |
| Buchmann, R | 1 |
| Conrads, G | 1 |
| Sculean, A | 1 |
| Rizzo, A | 1 |
| Paolillo, R | 1 |
| Guida, L | 1 |
| Annunziata, M | 1 |
| Bevilacqua, N | 1 |
| Tufano, MA | 1 |
| Houx, L | 1 |
| Brochard, S | 1 |
| Peudenier, S | 1 |
| Dam Hieu, P | 1 |
| Rémy-Néris, O | 1 |
| Senhorinho, GN | 1 |
| Nakano, V | 1 |
| Liu, C | 1 |
| Song, Y | 1 |
| Finegold, SM | 1 |
| Avila-Campos, MJ | 1 |
| Voillet, F | 1 |
| Charmensat, O | 1 |
| Castanier, M | 1 |
| Roch, A | 1 |
| Papazian, L | 1 |
| Brook, I | 1 |
| Mombelli, A | 1 |
| Samaranayake, LP | 1 |
| Ehmke, B | 1 |
| Moter, A | 1 |
| Beikler, T | 1 |
| Milian, E | 1 |
| Flemmig, TF | 1 |
| Austin, MN | 1 |
| Beigi, RH | 1 |
| Meyn, LA | 1 |
| Hillier, SL | 1 |
| Thouvenin, M | 1 |
| Schuhmacher, H | 1 |
| Gospodarek, E | 1 |
| Tyloch, F | 1 |
| Tyloch, J | 1 |
| Yu, X | 1 |
| Weng, L | 1 |
| Song, X | 1 |
| Timmerman, MF | 1 |
| Vangsted, T | 1 |
| Van der Velden, U | 2 |
| Wang, R | 1 |
| Ni, K | 1 |
| Deng, F | 1 |
| Tang, Z | 1 |
| Liu, B | 1 |
| Wang, C | 1 |
| Jian, X | 1 |
| Falkler, WA | 1 |
| Enwonwu, CO | 1 |
| Idigbe, EO | 1 |
| Alegre-Sancho, JJ | 1 |
| Juanola, X | 1 |
| Narvaez, FJ | 1 |
| Roig-Escofet, D | 1 |
| Kuriyama, T | 1 |
| Karasawa, T | 1 |
| Nakagawa, K | 1 |
| Yamamoto, E | 1 |
| Nakamura, S | 1 |
| Caiafa, AM | 1 |
| Sandoe, JA | 1 |
| Struthers, JK | 1 |
| Brazier, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of the Use of Metronidazole After Laparoscopic Hysterectomy for the Prevention of Vaginal Cellulitis or Vaginal Cuff Abscess. Multicentric Triple-blind Randomized Controlled Trial[NCT03917134] | 600 participants (Anticipated) | Interventional | 2019-05-01 | Not yet recruiting | |||
| The Use of Single Dose vs Short-Term Peri-Operative Cefazolin in the Prevention of Surgical Site Infection Following Orthognathic Surgery[NCT05852158] | Phase 4 | 400 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for metronidazole and Bacteroidaceae Infections
| Article | Year |
|---|---|
Topical and systemic antibiotics in the management of periodontal diseases.
Topics: Actinobacillus Infections; Administration, Oral; Administration, Topical; Aggregatibacter actinomyce | 2004 |
7 trials available for metronidazole and Bacteroidaceae Infections
| Article | Year |
|---|---|
Exploring potential of vaginal Lactobacillus isolates from South African women for enhancing treatment for bacterial vaginosis.
Topics: Adolescent; Adult; Bacteroidaceae Infections; Clindamycin; Drug Resistance, Bacterial; Female; Gardn | 2020 |
Short-term effects of systemic antibiotics during periodontal healing.
Topics: Actinobacillus Infections; Adult; Aggregatibacter actinomycetemcomitans; Aggressive Periodontitis; A | 2010 |
Adjunctive antimicrobial therapy of periodontitis: long-term effects on disease progression and oral colonization.
Topics: Actinobacillus Infections; Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Bacterial Agents | 2005 |
Microbiologic response to treatment of bacterial vaginosis with topical clindamycin or metronidazole.
Topics: Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Bacteroidaceae; Bacteroidaceae In | 2005 |
[The effect of tinidazole in the treatment of adult periodontitis].
Topics: Adult; Anti-Bacterial Agents; Bacteroidaceae Infections; Female; Humans; Male; Metronidazole; Middle | 1996 |
Additional clinical and microbiological effects of amoxicillin and metronidazole after initial periodontal therapy.
Topics: Actinobacillus Infections; Adult; Aggregatibacter actinomycetemcomitans; Amoxicillin; Anti-Bacterial | 1998 |
[A study of anaerobic infection in maxillofacial region].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteroidaceae Infections; Child; Child, Preschool; | 1997 |
30 other studies available for metronidazole and Bacteroidaceae Infections
| Article | Year |
|---|---|
Activity of pradofloxacin against Porphyromonas and Prevotella spp. Implicated in periodontal disease in dogs: susceptibility test data from a European multicenter study.
Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Dog Diseases; Dogs; Europe; Fluoroquinolo | 2008 |
Metronidazole resistance in Prevotella spp. and description of a new nim gene in Prevotella baroniae.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Blotting, Southern; Cross Infection; DNA, Bacteria | 2010 |
BMAL1-Downregulation Aggravates
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apolipoproteins E; ARNTL Transcription Factors; Athero | 2020 |
Intracranial abscess due to Prevotella bivia: First case report from India.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Brain Abscess; Combined Modality Therapy; Humans; | 2020 |
Infected breast cyst due to Prevotella buccae resistant to metronidazole.
Topics: Abscess; Bacteroidaceae Infections; Breast Cyst; Combined Modality Therapy; Drainage; Drug Resistanc | 2017 |
Sonographic detection of an infected maternal urachal cyst during pregnancy.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; | 2018 |
Clinical sources and antimicrobial susceptibility of Prevotella timonensis at the university hospital of Montpellier, France.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroidace | 2018 |
A multicenter survey of antimicrobial susceptibility of Prevotella species as determined by Etest methodology.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteroidaceae Infections; Clindamycin; Disk Diffusion Antimicrob | 2018 |
Three metronidazole-resistant Prevotella bivia strains harbour a mobile element, encoding a novel nim gene, nimK, and an efflux small MDR transporter.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; DNA, Bacterial; Drug Resistance, Bacterial; Genes, | 2018 |
Antimicrobial resistance and prevalence of resistance genes of obligate anaerobes isolated from periodontal abscesses.
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Proteins; Bacteriological Techniq | 2014 |
Polymersome-mediated intracellular delivery of antibiotics to treat Porphyromonas gingivalis-infected oral epithelial cells.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Cells, Cultured; Doxycycline; Gingiva; Gingival Di | 2013 |
Sonication assisted microbiological diagnosis of implant-related infection caused by Prevotella disiens and Staphylococcus epidermidis in a patient with cranioplasty.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Daptomycin; Humans; Male; Metronidazole; Middle Ag | 2015 |
Is Porphyromonas gingivalis cell invasion required for atherogenesis? Pharmacotherapeutic implications.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Bacteroidaceae Infections; Cell Line; Cholesterol; Diet | 2009 |
Septic arthritis of the knee joint secondary to Prevotella bivia.
Topics: Aged; Anti-Infective Agents; Arthritis, Infectious; Bacteroidaceae Infections; Humans; Knee Joint; M | 2009 |
Meningitis and epidural abscess related to pansinusitis.
Topics: Bacteroidaceae Infections; Cefotaxime; Ceftriaxone; Child; Combined Modality Therapy; Consciousness | 2009 |
Antibiotics in periodontics: right or wrong?
Topics: Amoxicillin; Anti-Bacterial Agents; Bacteroidaceae Infections; Combined Modality Therapy; Dental Pla | 2009 |
Effect of metronidazole and modulation of cytokine production on human periodontal ligament cells.
Topics: Adult; Anti-Infective Agents; Bacteroidaceae Infections; Cell Proliferation; Cell Survival; Cells, C | 2010 |
Recovery after tetraplegia caused by dermal sinus infection: intramedullary abscess and tetraparesis.
Topics: Anti-Infective Agents; Bacteroidaceae Infections; Brain Abscess; Cefotaxime; Humans; Infant; Magneti | 2011 |
Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis.
Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Clarithromycin; Dental Plaque; Dog Diseas | 2012 |
[Porphyromonas causing lung cavitation with empyema].
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Bronchoalveolar Lavage Fluid; Humans; Male; Metron | 2012 |
Prevotella intermedia meningitis associated with cerebrospinal fluid leakage in an adolescent.
Topics: Adolescent; Bacteroidaceae Infections; Ceftriaxone; Cerebrospinal Fluid Otorrhea; Craniocerebral Tra | 2003 |
Bacteremia caused by a metronidazole-resistant Prevotella sp. strain.
Topics: Aged; Anti-Infective Agents; Bacteremia; Bacteroidaceae Infections; Drug Resistance, Bacterial; Gene | 2005 |
[Bacteroides melaninogenicus, during Fournier's gangrene].
Topics: Bacteroidaceae Infections; Combined Modality Therapy; Fasciitis; Gangrene; Humans; Male; Metronidazo | 1994 |
[Clinical analysis of bacterial vaginosis in 76 cases].
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteroidaceae Infections; Drugs, Chinese Herbal; Female; Humans | 1996 |
Effects of metronidazole in patients with "refractory" periodontitis associated with Bacteroides forsythus.
Topics: Adult; Aggregatibacter actinomycetemcomitans; Anaerobiosis; Anti-Bacterial Agents; Bacteroidaceae In | 1997 |
Isolation of Fusobacterium necrophorum from cancrum oris (noma).
Topics: Adolescent; Anti-Bacterial Agents; Bacteroidaceae Infections; Child; Child, Preschool; Clindamycin; | 1999 |
Septic arthiritis due to Prevotella bivia in a patient with rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Aged; Arthritis, Infectious; Arthritis, Rheumatoid; Bacteroidaceae Infectio | 2000 |
Incidence of beta-lactamase production and antimicrobial susceptibility of anaerobic gram-negative rods isolated from pus specimens of orofacial odontogenic infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin Resistance; Anti-Bacterial Agents; Bacteroida | 2001 |
In vitro antimicrobial susceptibilities of three Porphyromonas spp and responses in the oral cavity of cats to treatment with selected antimicrobial drugs.
Topics: Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Cat Diseases; Cats; Clindamycin; Doxycycl | 2000 |
Subdural empyema caused by Prevotella loescheii with reduced susceptibility to metronidazole.
Topics: Anti-Bacterial Agents; Bacteroidaceae Infections; Drug Resistance, Microbial; Empyema, Subdural; Hum | 2001 |