metronidazole has been researched along with Bacteriuria in 7 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Bacteriuria: The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cefuroxime was successful, metronidazole failed in the prevention of minor morbidity." | 2.67 | Vaginal hysterectomy: cefuroxime, metronidazole or both? ( Kauer, FM; Manson, WL; Wijma, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Germano, C | 1 |
| Messina, A | 1 |
| Massaro, A | 1 |
| Attini, R | 1 |
| Leo, L | 1 |
| Manzoni, P | 1 |
| Masturzo, B | 1 |
| Poulsen, HK | 1 |
| Borel, J | 1 |
| Olsen, H | 1 |
| Chilaka, VN | 1 |
| Mayne, CJ | 1 |
| Ruol, A | 1 |
| Bertiato, G | 1 |
| Boscarin, S | 1 |
| Cusinato, R | 1 |
| Pascarella, M | 1 |
| Tonin, EA | 1 |
| Santi, S | 1 |
| Ancona, E | 1 |
| Kauer, FM | 1 |
| Wijma, J | 1 |
| Manson, WL | 1 |
| Gerber, B | 1 |
| Wilken, H | 1 |
| Watson, RA | 1 |
2 reviews available for metronidazole and Bacteriuria
| Article | Year |
|---|---|
Maternal Origins of Neonatal Infections: What Do Obstetrician-Gynecologist Should/Could Do?
Topics: Ampicillin; Anti-Bacterial Agents; Bacteriuria; Cesarean Section; Chorioamnionitis; Clindamycin; Com | 2022 |
Gardnerella vaginalis: genitourinary pathogen in men.
Topics: Adult; Bacteriuria; Balanitis; Child; Culture Media; Cystitis; Female; Gardnerella vaginalis; Genita | 1985 |
1 trial available for metronidazole and Bacteriuria
| Article | Year |
|---|---|
Vaginal hysterectomy: cefuroxime, metronidazole or both?
Topics: Adult; Aged; Bacterial Infections; Bacteriuria; Body Fluids; Cefuroxime; Double-Blind Method; Drug T | 1990 |
4 other studies available for metronidazole and Bacteriuria
| Article | Year |
|---|---|
[Changes in the microflora after abdominal hysterectomy].
Topics: Bacteria, Aerobic; Bacteria, Anaerobic; Bacteriuria; Female; Humans; Hysterectomy; Metronidazole; Pr | 1983 |
Postoperative urinary tract infections (UTIs) following single-dose intraoperative antibiotic prophylaxis in colposuspension patients.
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Antibiotic Prophylaxi | 1998 |
Short-Term prophylaxis with ceftriaxone plus metronidazole in esophageal cancer surgery.
Topics: Adult; Aged; Aged, 80 and over; Antibiotic Prophylaxis; Bacteriuria; Ceftriaxone; Drug Administratio | 2000 |
[Effectiveness of perioperative preventive use of antibiotics with metronidazole or doxycycline in vaginal hysterectomy].
Topics: Administration, Rectal; Bacteriuria; Doxycycline; Drug Administration Schedule; Female; Humans; Hyst | 1989 |