metronidazole has been researched along with Bacterial Sexually Transmitted Disease in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Whether bacterial vaginosis (BV) is acquired from an endogenous or an exogenous source is subject to controversy." | 2.43 | Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma. ( Bergström, M; Forsum, U; Jacobsson, B; Larsson, PG; Strand, A; Wölner-Hanssen, P, 2005) |
| "Bacterial vaginosis is also associated with preterm delivery in certain risk groups, such as women with a history of preterm birth or of low maternal weight." | 2.41 | Treatment of sexually transmitted bacterial diseases in pregnant women. ( Donders, GG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vinagre-Rodríguez, G | 1 |
| Fernandez-Gonzalez, N | 1 |
| Hernandez-Alonso, M | 1 |
| Martinez Quintana, E | 1 |
| Molina-Infante, J | 1 |
| Mary, N | 1 |
| Mahmood, TA | 1 |
| Kirkcaldy, RD | 1 |
| Augostini, P | 1 |
| Asbel, LE | 1 |
| Bernstein, KT | 1 |
| Kerani, RP | 1 |
| Mettenbrink, CJ | 1 |
| Pathela, P | 1 |
| Schwebke, JR | 1 |
| Secor, WE | 1 |
| Workowski, KA | 1 |
| Davis, D | 1 |
| Braxton, J | 1 |
| Weinstock, HS | 1 |
| Larsson, PG | 1 |
| Bergström, M | 1 |
| Forsum, U | 1 |
| Jacobsson, B | 1 |
| Strand, A | 1 |
| Wölner-Hanssen, P | 1 |
| Donders, GG | 1 |
3 reviews available for metronidazole and Bacterial Sexually Transmitted Disease
| Article | Year |
|---|---|
Preventing infective complications relating to induced abortion.
Topics: Abortion, Induced; Adolescent; Adult; Antibiotic Prophylaxis; Azithromycin; Cost-Benefit Analysis; D | 2010 |
Bacterial vaginosis. Transmission, role in genital tract infection and pregnancy outcome: an enigma.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Clindamycin; Disease Transmission, Infectious; Female; | 2005 |
Treatment of sexually transmitted bacterial diseases in pregnant women.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azithromycin; Erythromycin; Female; Humans; Metronidaz | 2000 |
3 other studies available for metronidazole and Bacterial Sexually Transmitted Disease
| Article | Year |
|---|---|
[Intestinal spirochetosis: A rare cause of chronic diarrhea].
Topics: Adult; Anti-Bacterial Agents; Chronic Disease; Colitis; Diarrhea; Homosexuality, Male; Humans; Intes | 2015 |
Trichomonas vaginalis antimicrobial drug resistance in 6 US cities, STD Surveillance Network, 2009-2010.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Drug Resistance, Bacterial; Female; Humans; Metronid | 2012 |
Drugs for sexually transmitted infections.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antitrichomonal Agents; Azithromycin; Chlamydia | 1999 |