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metronidazole and Bacterial Overgrowth Syndrome

metronidazole has been researched along with Bacterial Overgrowth Syndrome in 4 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"We describe a 52-year-old woman with panniculitis and blind loop syndrome."2.40Blind loop syndrome: an unusual cause of panniculitis. ( Caux, F; Dubertret, L; Halimi, C; Kevorkian, JP; Pinquier, L; Segrestaa, JM, 1997)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rao, SSC1
Bhagatwala, J1
Di Stefano, M1
Miceli, E1
Missanelli, A1
Mazzocchi, S1
Corazza, GR1
Caux, F1
Halimi, C1
Kevorkian, JP1
Pinquier, L1
Dubertret, L1
Segrestaa, JM1
Drenick, EJ1
Roslyn, JJ1

Reviews

2 reviews available for metronidazole and Bacterial Overgrowth Syndrome

ArticleYear
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
    Clinical and translational gastroenterology, 2019, Volume: 10, Issue:10

    Topics: Age Factors; Anti-Bacterial Agents; Bacteria; Blind Loop Syndrome; Breath Tests; Clinical Trials as

2019
Blind loop syndrome: an unusual cause of panniculitis.
    Journal of the American Academy of Dermatology, 1997, Volume: 37, Issue:5 Pt 2

    Topics: Animals; Biopsy; Blind Loop Syndrome; Breath Tests; Calcium; Feces; Female; Foot; Humans; Jejunostom

1997

Other Studies

2 other studies available for metronidazole and Bacterial Overgrowth Syndrome

ArticleYear
Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome.
    Alimentary pharmacology & therapeutics, 2005, Apr-15, Volume: 21, Issue:8

    Topics: Anti-Bacterial Agents; Blind Loop Syndrome; Breath Tests; Humans; Hydrogen; Intestinal Absorption; M

2005
Cure of arthritis-dermatitis syndrome due to intestinal bypass by resection of nonfunctional segment of blind loop.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:5

    Topics: Arthritis; Blind Loop Syndrome; Dermatitis; Female; Humans; Jejunoileal Bypass; Metronidazole; Middl

1990