metronidazole has been researched along with Bacterial Overgrowth Syndrome in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Excerpt | Relevance | Reference |
---|---|---|
"We describe a 52-year-old woman with panniculitis and blind loop syndrome." | 2.40 | Blind loop syndrome: an unusual cause of panniculitis. ( Caux, F; Dubertret, L; Halimi, C; Kevorkian, JP; Pinquier, L; Segrestaa, JM, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Rao, SSC | 1 |
Bhagatwala, J | 1 |
Di Stefano, M | 1 |
Miceli, E | 1 |
Missanelli, A | 1 |
Mazzocchi, S | 1 |
Corazza, GR | 1 |
Caux, F | 1 |
Halimi, C | 1 |
Kevorkian, JP | 1 |
Pinquier, L | 1 |
Dubertret, L | 1 |
Segrestaa, JM | 1 |
Drenick, EJ | 1 |
Roslyn, JJ | 1 |
2 reviews available for metronidazole and Bacterial Overgrowth Syndrome
Article | Year |
---|---|
Small Intestinal Bacterial Overgrowth: Clinical Features and Therapeutic Management.
Topics: Age Factors; Anti-Bacterial Agents; Bacteria; Blind Loop Syndrome; Breath Tests; Clinical Trials as | 2019 |
Blind loop syndrome: an unusual cause of panniculitis.
Topics: Animals; Biopsy; Blind Loop Syndrome; Breath Tests; Calcium; Feces; Female; Foot; Humans; Jejunostom | 1997 |
2 other studies available for metronidazole and Bacterial Overgrowth Syndrome
Article | Year |
---|---|
Absorbable vs. non-absorbable antibiotics in the treatment of small intestine bacterial overgrowth in patients with blind-loop syndrome.
Topics: Anti-Bacterial Agents; Blind Loop Syndrome; Breath Tests; Humans; Hydrogen; Intestinal Absorption; M | 2005 |
Cure of arthritis-dermatitis syndrome due to intestinal bypass by resection of nonfunctional segment of blind loop.
Topics: Arthritis; Blind Loop Syndrome; Dermatitis; Female; Humans; Jejunoileal Bypass; Metronidazole; Middl | 1990 |