metronidazole has been researched along with Back Ache in 4 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anaerobic organisms are a rare cause of spondylodiscitis." | 1.35 | Eggerthella lenta as a cause of anaerobic spondylodiscitis. ( Bok, CW; Ng, YS, 2009) |
| "Anidulafungin was used to treat invasive candidiasis in seven patients (20%) and candidemia in 10 patients (29%); Candida albicans or Candida glabrata was isolated most frequently in these two infections combined (7 isolates each [41%]/17 infections)." | 1.35 | Early clinical experience with anidulafungin at a large tertiary care medical center. ( Brielmaier, BD; Casabar, E; Kurtzeborn, CM; McKinnon, PS; Ritchie, DJ, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carter, C | 1 |
| Viveash, S | 1 |
| Kerhuel, L | 1 |
| Valade, S | 1 |
| Donay, JL | 1 |
| Canet, E | 1 |
| Bok, CW | 1 |
| Ng, YS | 1 |
| Brielmaier, BD | 1 |
| Casabar, E | 1 |
| Kurtzeborn, CM | 1 |
| McKinnon, PS | 1 |
| Ritchie, DJ | 1 |
4 other studies available for metronidazole and Back Ache
| Article | Year |
|---|---|
Nursing a critically ill tetanus patient in an intensive care unit in Zambia.
Topics: Analgesics, Opioid; Anti-Infective Agents; Anticonvulsants; Back Pain; Critical Care Nursing; Critic | 2017 |
Angina, back pain and septic shock.
Topics: Amoxicillin; Angina, Unstable; Anti-Bacterial Agents; Back Pain; Fusobacterium necrophorum; Humans; | 2017 |
Eggerthella lenta as a cause of anaerobic spondylodiscitis.
Topics: Actinobacteria; Aged, 80 and over; Anti-Bacterial Agents; Back Pain; Discitis; Drug Therapy, Combina | 2009 |
Early clinical experience with anidulafungin at a large tertiary care medical center.
Topics: Academic Medical Centers; Alanine Transaminase; Anidulafungin; Antifungal Agents; Aspartate Aminotra | 2008 |