metronidazole has been researched along with Babesia Infection in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Efficacy of oral administration of a doxycycline-enrofloxacin-metronidazole combination with and without injections of diminazene diaceturate in the management of naturally occurring canine babesiosis caused by B." | 1.36 | Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni. ( Huang, HP; Lin, MY, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Almendros, A | 1 |
| Burchell, R | 1 |
| Wierenga, J | 1 |
| Hwang, SJ | 1 |
| Yamasaki, M | 1 |
| Nakamura, K | 1 |
| Sasaki, N | 1 |
| Murakami, M | 1 |
| Wickramasekara Rajapakshage, BK | 1 |
| Ohta, H | 1 |
| Maede, Y | 1 |
| Takiguchi, M | 1 |
| Lin, MY | 1 |
| Huang, HP | 1 |
| Suzuki, K | 1 |
| Wakabayashi, H | 1 |
| Takahashi, M | 1 |
| Fukushima, K | 1 |
| Yabuki, A | 1 |
| Endo, Y | 1 |
| Miller, LH | 1 |
| Neva, FA | 1 |
| Gill, F | 1 |
| Fowler, JL | 1 |
| Ruff, MD | 1 |
| Fernau, RC | 1 |
| Furusho, Y | 1 |
1 trial available for metronidazole and Babesia Infection
| Article | Year |
|---|---|
A Possible treatment strategy and clinical factors to estimate the treatment response in Bebesia gibsoni infection.
Topics: Animals; Babesia; Babesiosis; C-Reactive Protein; Clindamycin; Dog Diseases; Dogs; Doxycycline; Drug | 2007 |
5 other studies available for metronidazole and Babesia Infection
| Article | Year |
|---|---|
An alternative combination therapy with metronidazole, clindamycin and doxycycline for Babesia gibsoni (Asian genotype) in dogs in Hong Kong.
Topics: Animals; Babesia; Babesiosis; Clindamycin; Dog Diseases; Dogs; Doxycycline; Female; Genotype; Hong K | 2020 |
Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Cell Division; Clindamycin; Diminazene; Dog Dise | 2010 |
Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Diminazene; Dog Diseases; Dogs; Doxycycline; Dru | 2010 |
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.
Topics: Animals; Babesiosis; Benzamidines; Chloroquine; Cricetinae; Drug Resistance; Humans; Male; Metronida | 1978 |
Babesia gibsoni: chemotherapy in dogs.
Topics: Administration, Oral; Amidines; Animals; Arsenicals; Azo Compounds; Babesiosis; Carbamates; Chloroqu | 1972 |