Page last updated: 2024-10-31

metronidazole and B. coli Infection

metronidazole has been researched along with B. coli Infection in 14 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Research Excerpts

ExcerptRelevanceReference
"Secnidazole was 89."2.78Prevalence, hematology, and treatment of balantidiasis among donkeys in and around Lahore, Pakistan. ( Abbas, T; Ali, MM; Avais, M; Ijaz, M; Khan, A; Khan, MS, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hazarika, M1
Pai H, V1
Khanna, V1
Reddy, H1
Tilak, K1
Chawla, K1
Khan, A1
Khan, MS1
Avais, M1
Ijaz, M1
Ali, MM1
Abbas, T1
Zrubec, J2
Wolfe, MS1
Nishiyama, T1
Ishida, T1
Takeuchi, H1
Nicholson, NW1
Garcia-Laverde, A1
de Bonilla, L1
Apted, FI2
Cannon, DA1
Huggins, D1
Beasley, JW1
Walzer, PD1
Zaman, V1
Natarajan, PN1

Reviews

6 reviews available for metronidazole and B. coli Infection

ArticleYear
The treatment of intestinal protozoan infections.
    The Medical clinics of North America, 1982, Volume: 66, Issue:3

    Topics: Amebicides; Antimalarials; Antiprotozoal Agents; Balantidiasis; Chloroquine; Coccidiosis; Dientamoeb

1982
[Balantidiosis coli].
    Ryoikibetsu shokogun shirizu, 1999, Issue:24 Pt 2

    Topics: Animals; Anti-Bacterial Agents; Antitrichomonal Agents; Balantidiasis; Balantidium; Diagnosis, Diffe

1999
Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.
    Tropical diseases bulletin, 1971, Volume: 68, Issue:2

    Topics: Amebiasis; Animals; Balantidiasis; Coccidiosis; Emetine; Entamoeba; Entamoeba histolytica; Giardiasi

1971
Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.
    Tropical diseases bulletin, 1972, Volume: 69, Issue:2

    Topics: Amebiasis; Animals; Balantidiasis; Complement Fixation Tests; Cricetinae; Dogs; Entamoeba histolytic

1972
Summary of recent abstracts. II. Amoebiasis and intestinal protozoal infections.
    Tropical diseases bulletin, 1973, Volume: 70, Issue:2

    Topics: Amebiasis; Animals; Balantidiasis; Complement Fixation Tests; Dysentery, Amebic; Entamoeba histolyti

1973
[Management of parasitic intestinal diseases].
    Revista brasileira de medicina, 1968, Volume: 25, Issue:10

    Topics: Amebicides; Anthelmintics; Balantidiasis; Brazil; Chloroquine; Chloroquinolinols; Dysentery, Amebic;

1968

Trials

2 trials available for metronidazole and B. coli Infection

ArticleYear
Prevalence, hematology, and treatment of balantidiasis among donkeys in and around Lahore, Pakistan.
    Veterinary parasitology, 2013, Sep-01, Volume: 196, Issue:1-2

    Topics: Animals; Antiprotozoal Agents; Balantidiasis; Equidae; Female; Male; Metronidazole; Nigella sativa;

2013
Clinical trials with metronidazole in human balantidiasis.
    The American journal of tropical medicine and hygiene, 1975, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Animals; Balantidiasis; Balantidium; Child; Child, Preschool; Dose-Response Relat

1975

Other Studies

6 other studies available for metronidazole and B. coli Infection

ArticleYear
Rare Case of Polymicrobial Keratitis With Balantidium coli.
    Cornea, 2016, Volume: 35, Issue:12

    Topics: Anti-Bacterial Agents; Antiprotozoal Agents; Balantidiasis; Balantidium; Coinfection; Contact Lenses

2016
[Balantidiasis in children and its treatment with metrodiazole].
    Bratislavske lekarske listy, 1967, Feb-28, Volume: 47, Issue:4

    Topics: Balantidiasis; Child; Female; Humans; Male; Metronidazole; Trichuriasis

1967
Case report of Balantidium coli infection.
    East African medical journal, 1978, Volume: 55, Issue:3

    Topics: Balantidiasis; Humans; Male; Metronidazole; Middle Aged

1978
Ineffectiveness of metronidazole in treatment of Balantidium coli infections.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1972, Volume: 66, Issue:3

    Topics: Adult; Balantidiasis; Female; Humans; Infant; Male; Metronidazole; Middle Aged

1972
[Experience with the clinical diagnosis and therapy of balantidiasis].
    Ceskoslovenska pediatrie, 1970, Volume: 25, Issue:8

    Topics: Balantidiasis; Child; Diagnosis, Differential; Female; Humans; Intestinal Diseases, Parasitic; Metro

1970
In vitro trials of metronidazole against Balantidium coli.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1969, Volume: 63, Issue:1

    Topics: Animals; Balantidiasis; Balantidium; Humans; Metronidazole; Swine

1969