metronidazole has been researched along with B-Cell Lymphoma in 3 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Treatment with penicillin G was very effective in the acute stage, and chronic administration of metronidazole prevented relapse of the disease." | 1.35 | An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis. ( Fujimuro, M; Jackson, M; Kawarabayashi, T; Kimura, T; Matsubara, E; Nakahata, N; Seino, Y; Shirahama, I; Shoji, M; Suzuki, C; Takamura, A; Tomiyama, M; Wakasaya, Y; Watanabe, M; Yamamoto-Watanabe, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Robotis, J | 1 |
| Tsiodras, S | 1 |
| Rokkas, T | 1 |
| Wakasaya, Y | 1 |
| Watanabe, M | 1 |
| Tomiyama, M | 1 |
| Suzuki, C | 1 |
| Jackson, M | 1 |
| Fujimuro, M | 1 |
| Kimura, T | 1 |
| Seino, Y | 1 |
| Kawarabayashi, T | 1 |
| Yamamoto-Watanabe, Y | 1 |
| Matsubara, E | 1 |
| Shirahama, I | 1 |
| Takamura, A | 1 |
| Nakahata, N | 1 |
| Shoji, M | 1 |
| Furusyo, N | 1 |
| Kanamoto, K | 1 |
| Nakamura, S | 1 |
| Yao, T | 1 |
| Suekane, H | 1 |
| Yano, Y | 1 |
| Ariyama, I | 1 |
| Hayashi, J | 1 |
| Kashiwagi, S | 1 |
3 other studies available for metronidazole and B-Cell Lymphoma
| Article | Year |
|---|---|
Helicobacter pylori eradication may successfully treat primary cutaneous follicle center lymphoma.
Topics: Amoxicillin; Anti-Bacterial Agents; Bismuth; Clarithromycin; Doxycycline; Female; Helicobacter Infec | 2018 |
An unusual case of chronic relapsing tetanus associated with mandibular osteomyelitis.
Topics: Anti-Bacterial Agents; Chronic Disease; Gallium Radioisotopes; Head and Neck Neoplasms; Humans; Lymp | 2009 |
Rapidly growing primary gastric B-cell lymphoma after eradication of Helicobacter pylori.
Topics: Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Gastrointestinal Neoplasms; Helicobacter I | 1999 |