metronidazole has been researched along with Avian Diseases in 15 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole has been used for many years in the treatment of birds’ trichomonosis." | 1.72 | Antitrichomonal activity of nanoemulsion of carvacrol on Trichomonas galline: formulation development and in vitro characterization. ( Tabari, MA; Yazdani, N; Youssefi, MR, 2022) |
| " The in vivo assay was done on 60 experimentally infected pigeons dosed with metronidazole at 50 mg/kg body weight (BW) or alkaloids at 25 mg/kg BW." | 1.46 | Antitrichomonal activity of Peganum harmala alkaloid extract against trichomoniasis in pigeon (Columba livia domestica). ( Moghadamnia, AA; Tabari, MA; Youssefi, MR, 2017) |
| "Metronidazole was administered at various dose rates by crop gavage or in drinking water to eight groups of five to ten finches each." | 1.30 | Cochlosoma infections in finches. ( Filippich, LJ; O'Donoghue, PJ, 1997) |
| "Dimetridazole was formulated for drinking water medication and as a prolonged-release tablet." | 1.29 | Pharmacokinetics and anti-trichomonal efficacy of a dimetridazole tablet and water-soluble powder in homing pigeons (Columba livia). ( DeBacker, P; Inghelbrecht, S; Remon, JP; Ronsmans, S; Vercruysse, J; Vermeersch, H, 1996) |
| "Praziquantel administered at a dosage of 10 mg/kg of body weight/day for 14 days eliminated a fluke infection in a red-billed toucan." | 1.27 | Treatment of flukes in a toucan. ( Giddings, RF, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (13.33) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yazdani, N | 1 |
| Youssefi, MR | 2 |
| Tabari, MA | 2 |
| Lind, MA | 1 |
| Sepp, T | 1 |
| Štšeglova, K | 1 |
| Hõrak, P | 1 |
| Zadravec, M | 1 |
| Slavec, B | 1 |
| Krapež, U | 1 |
| Gombač, M | 1 |
| Švara, T | 1 |
| Poljšak-Prijatelj, M | 1 |
| Gruntar, I | 1 |
| Račnik, J | 1 |
| Seddiek, ShA | 1 |
| El-Shorbagy, MM | 1 |
| Khater, HF | 1 |
| Ali, AM | 1 |
| Moghadamnia, AA | 1 |
| Zimre-Grabensteiner, E | 1 |
| Arshad, N | 1 |
| Amin, A | 1 |
| Hess, M | 1 |
| Samour, JH | 2 |
| Bailey, TA | 1 |
| Cooper, JE | 1 |
| Pennycott, TW | 1 |
| Inghelbrecht, S | 1 |
| Vermeersch, H | 1 |
| Ronsmans, S | 1 |
| Remon, JP | 1 |
| DeBacker, P | 1 |
| Vercruysse, J | 1 |
| Filippich, LJ | 1 |
| O'Donoghue, PJ | 1 |
| McKeon, T | 1 |
| Dunsmore, J | 1 |
| Raidal, SR | 1 |
| Bates, G | 1 |
| Tucker, RL | 1 |
| Ford, S | 1 |
| Mattix, ME | 1 |
| Giddings, RF | 1 |
| Lüthgen, W | 1 |
| Bernau, U | 1 |
1 trial available for metronidazole and Avian Diseases
| Article | Year |
|---|---|
Effect of four therapeutic agents on Trichomonas phasiani carriage in pheasants.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites; Antiprotozoal Agents; Antitrichomonal Agents; Bird | 1996 |
14 other studies available for metronidazole and Avian Diseases
| Article | Year |
|---|---|
Antitrichomonal activity of nanoemulsion of carvacrol on Trichomonas galline: formulation development and in vitro characterization.
Topics: Animals; Antitrichomonal Agents; Bird Diseases; Columbidae; Cymenes; Metronidazole; Protamines; Tric | 2022 |
Antibiotic treatment increases yellowness of carotenoid feather coloration in male greenfinches (Chloris chloris).
Topics: Animals; Anti-Bacterial Agents; Bird Diseases; Body Mass Index; Carotenoids; Coccidiostats; Color; F | 2021 |
Trichomonosis outbreak in a flock of canaries (Serinus canaria f. domestica) caused by a finch epidemic strain of Trichomonas gallinae.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Bird Diseases; Canaries; Disease Outbreaks; DNA | 2017 |
The antitrichomonal efficacy of garlic and metronidazole against Trichomonas gallinae infecting domestic pigeons.
Topics: Animals; Antitrichomonal Agents; Bird Diseases; Columbidae; Garlic; Metronidazole; Plant Extracts; T | 2014 |
Antitrichomonal activity of Peganum harmala alkaloid extract against trichomoniasis in pigeon (Columba livia domestica).
Topics: Animals; Antitrichomonal Agents; Bird Diseases; Columbidae; Harmaline; Harmine; Metronidazole; Pegan | 2017 |
Genetically different clonal isolates of Trichomonas gallinae, obtained from the same bird, can vary in their drug susceptibility, an in vitro evidence.
Topics: Animals; Antitrichomonal Agents; Bird Diseases; Columbidae; Dimetridazole; Genes, Protozoan; Genetic | 2011 |
Trichomoniasis in birds of prey (order Falconiformes) in Bahrain.
Topics: Air Sacs; Animals; Bahrain; Bird Diseases; Birds; Crop, Avian; Dimetridazole; Electrolytes; Esophage | 1995 |
Pharmacokinetics and anti-trichomonal efficacy of a dimetridazole tablet and water-soluble powder in homing pigeons (Columba livia).
Topics: Animals; Antiprotozoal Agents; Biological Availability; Bird Diseases; Columbidae; Delayed-Action Pr | 1996 |
Cochlosoma infections in finches.
Topics: Animals; Animals, Domestic; Antiprotozoal Agents; Bird Diseases; Birds; Body Weight; Colon; Data Col | 1997 |
Trichomonas gallinae in budgerigars and columbid birds in Perth, Western Australia.
Topics: Animals; Animals, Wild; Antiprotozoal Agents; Antitrichomonal Agents; Bird Diseases; Birds; Dimetrid | 1997 |
Thyroid adenocarcinoma in a bald eagle (Haliaeetus leukocephalus).
Topics: Adenocarcinoma; Animals; Antitrichomonal Agents; Bird Diseases; Eagles; Female; Hemorrhage; Metronid | 1999 |
Supraorbital trichomoniasis infection in two saker falcons (Falco cherrug).
Topics: Administration, Topical; Animals; Anti-Infective Agents; Antitrichomonal Agents; Bird Diseases; Colu | 2000 |
Treatment of flukes in a toucan.
Topics: Animals; Bird Diseases; Birds; Giardiasis; Metronidazole; Praziquantel; Trematode Infections | 1988 |
[Metronidazol for the control of trichomoniasis of pigeons].
Topics: Animals; Bird Diseases; Columbidae; Metronidazole; Trichomonas Infections | 1967 |