metronidazole has been researched along with Autoimmune Diseases in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Autoimmune Diseases: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, HD | 1 |
| Zhao, ZB | 1 |
| Ma, WT | 1 |
| Liu, QZ | 1 |
| Gao, CY | 1 |
| Li, L | 1 |
| Wang, J | 1 |
| Tsuneyama, K | 1 |
| Liu, B | 1 |
| Zhang, W | 1 |
| Zhou, Y | 1 |
| Gershwin, ME | 1 |
| Lian, ZX | 1 |
| Rashid Dar, N | 1 |
| Raza, N | 1 |
| Martínez, JG | 1 |
| Saus, C | 1 |
| Morey, A | 1 |
| Alarcón, A | 1 |
| García Pérez, A | 1 |
| Valverde de La Osa, J | 1 |
| Giménez Samper, M | 1 |
| Alonso García, I | 1 |
| Müller, H | 1 |
| Rappel, S | 1 |
| Wündisch, T | 1 |
| Bayerdörffer, E | 1 |
| Stolte, M | 1 |
5 other studies available for metronidazole and Autoimmune Diseases
| Article | Year |
|---|---|
Gut microbiota translocation promotes autoimmune cholangitis.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Autoimmune Diseases; Bacterial Translocation; Bile Ducts | 2018 |
Drug induced linear IgA disease with unusual features: Koebner phenomenon, local insulin sensitivity and annular blister of the nipples.
Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Butylscopolammonium Bromide; Drug Eruptions; Huma | 2008 |
[Crohn's disease and renal amyloidosis. Acute renal failure].
Topics: Acetaminophen; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Amyloidosis; Analgesics, Non-Nar | 2002 |
[Resolution of an autoimmune thrombocytopenic purpura after eradicating treatment of Helicobacter pylori].
Topics: Adult; Amoxicillin; Anti-Ulcer Agents; Autoimmune Diseases; Bismuth; Drug Therapy, Combination; Fema | 1999 |
Healing of active, non-atrophic autoimmune gastritis by H. pylori eradication.
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Agents; Autoimmune Diseases; Clarithromycin; | 2001 |